Page last updated: 2024-10-29

2-propanol and Emesis, Postoperative

2-propanol has been researched along with Emesis, Postoperative in 10 studies

2-Propanol: An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
propan-2-ol : A secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Patients identified as high risk for postoperative nausea and vomiting (PONV) are often treated prophylactically with intravenous (IV) ondansetron and an additional agent."9.15Prophylactic isopropyl alcohol inhalation and intravenous ondansetron versus ondansetron alone in the prevention of postoperative nausea and vomiting in high-risk patients. ( Bushey, B; Daniel, C; Fuller, TN; Pellegrini, JE; Radford, KD, 2011)
"Frequently, patients identified as high risk for postoperative nausea and vomiting (PONV) are treated prophylactically with intravenous (IV) ondansetron and postoperatively with IV promethazine."9.14Comparison of inhalation of isopropyl alcohol vs promethazine in the treatment of postoperative nausea and vomiting (PONV) in patients identified as at high risk for developing PONV. ( Bennett, J; DeLoge, J; Kelly, J; Pellegrini, J, 2009)
"We evaluated preemptive treatment for postoperative nausea and vomiting (PONV) with intravenous (IV) granisetron, 0."9.12The effectiveness of inhalation isopropyl alcohol vs. granisetron for the prevention of postoperative nausea and vomiting. ( Hawkins, JK; Teran, L, 2007)
"Patients identified as high risk for postoperative nausea and vomiting (PONV) are often treated prophylactically with intravenous (IV) ondansetron and an additional agent."5.15Prophylactic isopropyl alcohol inhalation and intravenous ondansetron versus ondansetron alone in the prevention of postoperative nausea and vomiting in high-risk patients. ( Bushey, B; Daniel, C; Fuller, TN; Pellegrini, JE; Radford, KD, 2011)
"Frequently, patients identified as high risk for postoperative nausea and vomiting (PONV) are treated prophylactically with intravenous (IV) ondansetron and postoperatively with IV promethazine."5.14Comparison of inhalation of isopropyl alcohol vs promethazine in the treatment of postoperative nausea and vomiting (PONV) in patients identified as at high risk for developing PONV. ( Bennett, J; DeLoge, J; Kelly, J; Pellegrini, J, 2009)
"We evaluated preemptive treatment for postoperative nausea and vomiting (PONV) with intravenous (IV) granisetron, 0."5.12The effectiveness of inhalation isopropyl alcohol vs. granisetron for the prevention of postoperative nausea and vomiting. ( Hawkins, JK; Teran, L, 2007)
"Based on this study, it seems postoperative nausea can be resolved quicker using 70% inhaled isopropyl alcohol compared with intravenous ondansetron in women undergoing outpatient gynecologic laparoscopic procedures."2.71Comparison of inhaled isopropyl alcohol and intravenous ondansetron for treatment of postoperative nausea. ( Pellegrini, JE; Riley, GP; Rinehart, RS; Vacchiano, CA; Winston, AW, 2003)
"Overall satisfaction with postoperative nausea management was 86."2.71Aromatherapy with peppermint, isopropyl alcohol, or placebo is equally effective in relieving postoperative nausea. ( Anderson, LA; Gross, JB, 2004)
"Postoperative nausea and vomiting is a common and unpleasant phenomenon and current therapies are not always effective for all patients."2.48Aromatherapy for treatment of postoperative nausea and vomiting. ( Chang, A; Gibbons, K; Hines, S; Steels, E, 2012)
"PONV has a multifactor etiology, but there are ways to reduce its occurrence."2.44The effects of stimulation of acupressure point p6 on postoperative nausea and vomiting: a review of literature. ( Guinn, C; Nunley, C; Wakim, J, 2008)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's6 (60.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hines, S2
Steels, E2
Chang, A2
Gibbons, K2
Nunley, C1
Wakim, J1
Guinn, C1
Pellegrini, J1
DeLoge, J1
Bennett, J1
Kelly, J1
Schwartz, A1
Radford, KD1
Fuller, TN1
Bushey, B1
Daniel, C1
Pellegrini, JE2
Winston, AW1
Rinehart, RS1
Riley, GP1
Vacchiano, CA1
Anderson, LA1
Gross, JB1
Teran, L1
Hawkins, JK1
Smiler, BG1
Srock, M1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Remimazolam on Incidence of Postoperative Nausea and Vomiting Following General Anesthesia in High-risk Patients: a Multicenter, Double-blinded, Placebo-controlled Randomized Trial[NCT04861337]Phase 4552 participants (Actual)Interventional2021-05-19Completed
Inhalation Intervention for Nausea in the Emergency Department[NCT02092441]80 participants (Actual)Interventional2014-04-30Completed
Value of Ondansetron Medication vs Inhaled Isopropyl Therapy in the Emergency Department (VOMIITED)[NCT03125811]Early Phase 1121 participants (Actual)Interventional2017-07-17Completed
Isopropyl Alcohol Inhalation as Anti-emetic Therapy in the Emergency Department[NCT04464915]0 participants (Actual)Interventional2020-07-31Withdrawn (stopped due to Given the COVID-19 pandemic, there has been a temporary suspension of study activities, therefore the study has not yet been initiated.)
Aromatherapy for Management of Chemotherapy-induced Symptoms[NCT02670941]Early Phase 131 participants (Actual)Interventional2016-01-31Terminated (stopped due to Slow accrual; Received grant funding for a similar but different study.)
Nasally Inhaled Isopropyl Alcohol Versus Oral Ondansetron for the Treatment of Nausea in the Emergency Department: A Double-Blind Randomized Controlled Trial[NCT02760069]Phase 4122 participants (Actual)Interventional2016-01-31Completed
Aromatherapy as Prophylaxis for Prevention of Intrathecal Morphine Induced Nausea and Vomiting in Lower Segment Cesarean Section[NCT03434340]155 participants (Actual)Interventional2018-06-26Completed
Aromatherapy in Management of Postoperative Nausea in Post-Bariatric Surgery Patients[NCT03130218]204 participants (Actual)Interventional2017-06-08Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Nausea Verbal Numerical Rating Scale (0-10) at 10 Minutes Post Intervention

"Primary outcome is nausea and vomiting measured on a scale from 0 (no nausea) to 10 (worst nausea imaginable) Verbal Numerical Response Scale (VNRS) at 10 minutes post intervention." (NCT02092441)
Timeframe: 10 minutes post intervention

InterventionVNRS (Median)
Alcohol Prep Pad Group3
Normal Saline Prep Pad6

Satisfaction Measured on a 5-point Likert Scale

"Patient satisfaction of smelling prep pad to alleviate nausea on a scale from 1 (completely unsatisfied) to 5 (completely satisfied)" (NCT02092441)
Timeframe: 10 minutes post intervention

Intervention5 point Likert Scale (Median)
Alcohol Prep Pad Group4
Normal Saline Prep Pad2

Verbal Numerical Rating Scale Pain Score (0-10) at 10 Minutes Post Intervention

"Scale ranges from 0 (no pain) to 10 (worst pain imaginable)" (NCT02092441)
Timeframe: 10 minutes post intervention

InterventionVNRS (Median)
Alcohol Prep Pad Group6
Normal Saline Prep Pad6

Nausea 100 mm Visual Analogue Scale (VAS)

Full Scale Name: Nausea 100-mm visual analogue scale. Scale Construct: Measures nausea as reported by the patient Scale Range: Minimum is 0 (no nausea) to 100 (worst nausea imaginable). These values quantify, on an interval scale anchored at 0, the patient's subjective sensation of nausea. Higher values represent worse outcomes (e.g., more nausea). Patient makes a single vertical mark on a 100 mm horizontal line with 0 at the left and 100 on the right to depict their nausea. (NCT02760069)
Timeframe: 30 minutes post intervention

Interventionunits on a scale (Mean)
Inhaled ISO + Oral Ondansetron23
Inhaled ISO + Oral Placebo19
Inhaled Placebo + Oral Ondansetron42

Number of Participants Who Required Rescue Anti-emetics

Whether patient required rescue anti-emetics (binary variable). Measured using nurse drug administration record. (NCT02760069)
Timeframe: Study duration (up to 5 hours post intervention)

InterventionParticipants (Count of Participants)
Inhaled ISO + Oral Ondansetron11
Inhaled ISO + Oral Placebo10
Inhaled Placebo + Oral Ondansetron18

Reviews

3 reviews available for 2-propanol and Emesis, Postoperative

ArticleYear
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2018, 03-10, Volume: 3

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2018
The effects of stimulation of acupressure point p6 on postoperative nausea and vomiting: a review of literature.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2008, Volume: 23, Issue:4

    Topics: 2-Propanol; Acupressure; Acupuncture Points; Adult; Antiemetics; Child; Cholinergic Antagonists; Cos

2008
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012
Aromatherapy for treatment of postoperative nausea and vomiting.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Antiemetics; Aromatherapy; Controlled Clinical Trials as Top

2012

Trials

5 trials available for 2-propanol and Emesis, Postoperative

ArticleYear
Comparison of inhalation of isopropyl alcohol vs promethazine in the treatment of postoperative nausea and vomiting (PONV) in patients identified as at high risk for developing PONV.
    AANA journal, 2009, Volume: 77, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Adult; Antiemetics; Clinical Nursing Research; Female; Hista

2009
Comparison of inhalation of isopropyl alcohol vs promethazine in the treatment of postoperative nausea and vomiting (PONV) in patients identified as at high risk for developing PONV.
    AANA journal, 2009, Volume: 77, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Adult; Antiemetics; Clinical Nursing Research; Female; Hista

2009
Comparison of inhalation of isopropyl alcohol vs promethazine in the treatment of postoperative nausea and vomiting (PONV) in patients identified as at high risk for developing PONV.
    AANA journal, 2009, Volume: 77, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Adult; Antiemetics; Clinical Nursing Research; Female; Hista

2009
Comparison of inhalation of isopropyl alcohol vs promethazine in the treatment of postoperative nausea and vomiting (PONV) in patients identified as at high risk for developing PONV.
    AANA journal, 2009, Volume: 77, Issue:4

    Topics: 2-Propanol; Administration, Inhalation; Adult; Antiemetics; Clinical Nursing Research; Female; Hista

2009
Prophylactic isopropyl alcohol inhalation and intravenous ondansetron versus ondansetron alone in the prevention of postoperative nausea and vomiting in high-risk patients.
    AANA journal, 2011, Volume: 79, Issue:4 Suppl

    Topics: 2-Propanol; Administration, Inhalation; Adult; Antiemetics; Aromatherapy; Drug Therapy, Combination;

2011
Comparison of inhaled isopropyl alcohol and intravenous ondansetron for treatment of postoperative nausea.
    AANA journal, 2003, Volume: 71, Issue:2

    Topics: 2-Propanol; Administration, Inhalation; Adult; Antiemetics; Female; Humans; Injections, Intravenous;

2003
Comparison of inhaled isopropyl alcohol and intravenous ondansetron for treatment of postoperative nausea.
    AANA journal, 2003, Volume: 71, Issue:2

    Topics: 2-Propanol; Administration, Inhalation; Adult; Antiemetics; Female; Humans; Injections, Intravenous;

2003
Comparison of inhaled isopropyl alcohol and intravenous ondansetron for treatment of postoperative nausea.
    AANA journal, 2003, Volume: 71, Issue:2

    Topics: 2-Propanol; Administration, Inhalation; Adult; Antiemetics; Female; Humans; Injections, Intravenous;

2003
Comparison of inhaled isopropyl alcohol and intravenous ondansetron for treatment of postoperative nausea.
    AANA journal, 2003, Volume: 71, Issue:2

    Topics: 2-Propanol; Administration, Inhalation; Adult; Antiemetics; Female; Humans; Injections, Intravenous;

2003
Aromatherapy with peppermint, isopropyl alcohol, or placebo is equally effective in relieving postoperative nausea.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2004, Volume: 19, Issue:1

    Topics: 2-Propanol; Administration, Inhalation; Adult; Ambulatory Surgical Procedures; Analysis of Variance;

2004
The effectiveness of inhalation isopropyl alcohol vs. granisetron for the prevention of postoperative nausea and vomiting.
    AANA journal, 2007, Volume: 75, Issue:6

    Topics: 2-Propanol; Administration, Inhalation; Adolescent; Adult; Antiemetics; Female; Granisetron; Humans;

2007

Other Studies

2 other studies available for 2-propanol and Emesis, Postoperative

ArticleYear
Comparison of inhalation of isopropyl alcohol vs promethazine in the treatment of postoperative nausea and vomiting (PONV) in patients identified as high risk for developing PONV.
    AANA journal, 2009, Volume: 77, Issue:6

    Topics: 2-Propanol; Antiemetics; Humans; Ondansetron; Postoperative Nausea and Vomiting; Preanesthetic Medic

2009
Isopropyl alcohol for transport-related nausea.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:5

    Topics: 2-Propanol; Humans; Postoperative Nausea and Vomiting; Transportation of Patients

1998