2-propanol has been researched along with Catheter-Associated Infections in 18 studies
2-Propanol: An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
propan-2-ol : A secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Catheter connection antisepsis was changed from 70% isopropanol alone to 2% chlorhexidine in 70% isopropanol." | 7.75 | A fall in bloodstream infections followed a change to 2% chlorhexidine in 70% isopropanol for catheter connection antisepsis: a pediatric single center before/after study on a hemopoietic stem cell transplant ward. ( Bravery, K; Collins, J; Ho, A; Lock, P; Macqueen, S; Soothill, JS, 2009) |
| " Catheter connection antisepsis was changed from 70% isopropanol alone to 2% chlorhexidine in 70% isopropanol." | 3.75 | A fall in bloodstream infections followed a change to 2% chlorhexidine in 70% isopropanol for catheter connection antisepsis: a pediatric single center before/after study on a hemopoietic stem cell transplant ward. ( Bravery, K; Collins, J; Ho, A; Lock, P; Macqueen, S; Soothill, JS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 15 (83.33) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Hjalmarsson, LB | 1 |
| Hagberg, J | 1 |
| Schollin, J | 1 |
| Ohlin, A | 2 |
| Rickard, CM | 1 |
| Flynn, J | 1 |
| Larsen, E | 1 |
| Mihala, G | 1 |
| Playford, EG | 1 |
| Shaw, J | 1 |
| Keogh, S | 1 |
| Ullman, A | 1 |
| Zhang, L | 1 |
| Gavin, N | 1 |
| Kleidon, T | 1 |
| Chopra, V | 2 |
| McCarthy, AL | 1 |
| Rocha, PK | 1 |
| Marsh, N | 1 |
| Kieran, EA | 1 |
| O'Sullivan, A | 1 |
| Miletin, J | 1 |
| Twomey, AR | 1 |
| Knowles, SJ | 1 |
| O'Donnell, CPF | 1 |
| Brunelli, SM | 1 |
| Van Wyck, DB | 1 |
| Njord, L | 1 |
| Ziebol, RJ | 1 |
| Lynch, LE | 1 |
| Killion, DP | 1 |
| Maunoury, F | 1 |
| Farinetto, C | 1 |
| Ruckly, S | 1 |
| Guenezan, J | 1 |
| Lucet, JC | 2 |
| Lepape, A | 2 |
| Pascal, J | 1 |
| Souweine, B | 1 |
| Mimoz, O | 3 |
| Timsit, JF | 3 |
| Devrim, İ | 1 |
| Demiray, N | 1 |
| Oruç, Y | 1 |
| Sipahi, K | 1 |
| Çağlar, İ | 1 |
| Sarı, F | 1 |
| Turgut, N | 1 |
| Atakul, G | 1 |
| Özdamar, N | 1 |
| Dursun, V | 1 |
| Sorguç, Y | 1 |
| Bayram, N | 1 |
| Agın, H | 1 |
| Clarke, P | 1 |
| Craig, JV | 1 |
| Wain, J | 1 |
| Tremlett, C | 1 |
| Linsell, L | 1 |
| Bowler, U | 1 |
| Juszczak, E | 1 |
| Heath, PT | 1 |
| Clavier, T | 1 |
| Franchina, S | 1 |
| Lefevre-Scelles, A | 1 |
| Gouin, P | 1 |
| Besnier, E | 1 |
| Veber, B | 1 |
| Goudet, V | 1 |
| Balayn, D | 1 |
| Seguin, S | 1 |
| Björkman, L | 1 |
| Cullis, PS | 1 |
| Keene, DJ | 1 |
| Zaman, A | 1 |
| Barker, C | 1 |
| Govan, L | 1 |
| Minford, J | 1 |
| Restrepo, D | 1 |
| Laconi, NS | 1 |
| Alcantar, NA | 1 |
| West, LA | 1 |
| Buttice, AL | 1 |
| Patel, S | 1 |
| Kayton, ML | 1 |
| McCann, M | 1 |
| Fitzpatrick, F | 1 |
| Mellotte, G | 1 |
| Clarke, M | 1 |
| Soothill, JS | 1 |
| Bravery, K | 1 |
| Ho, A | 1 |
| Macqueen, S | 1 |
| Collins, J | 1 |
| Lock, P | 1 |
| Dettenkofer, M | 1 |
| Wilson, C | 1 |
| Gratwohl, A | 1 |
| Schmoor, C | 1 |
| Bertz, H | 1 |
| Frei, R | 1 |
| Heim, D | 1 |
| Luft, D | 1 |
| Schulz, S | 1 |
| Widmer, AF | 1 |
| Sannoh, S | 1 |
| Clones, B | 1 |
| Munoz, J | 1 |
| Montecalvo, M | 1 |
| Parvez, B | 1 |
| Lockman, JL | 1 |
| Heitmiller, ES | 1 |
| Ascenzi, JA | 1 |
| Berkowitz, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Product Evaluation for the Effectiveness of the ClearGuard® HD End Cap[NCT02593149] | 1,902 participants (Actual) | Interventional | 2015-11-30 | Completed | |||
| [NCT01629550] | Phase 4 | 2,400 participants | Interventional | 2012-10-31 | Completed | ||
| Skin Disinfection With Octenidine Dihydrochloride for the Prevention of Catheter-Associated Infections - A Double-Blind, Randomized, Controlled Trial[NCT00515151] | Phase 4 | 400 participants (Actual) | Interventional | 2002-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"This was calculated by dividing the cumulative number of PBCs by cumulative time at-risk as follows.~The National Healthcare Safety Network (NHSN) Center for Disease Control (CDC) 21-day outpatient hemodialysis patient rule is as follows: A PBC is considered a new event and counted only if it occurred 21 days or more after a previously reported PBC in the same patient; new PBC events are based on blood cultures drawn as an outpatient or within one calendar day after a hospital admission. Following a PBC additional same-type events were counted beginning 21 days following the initial event; the CVC-days were counted during this period. The CVC-days were calculated by summing the number of days each patient was at-risk of accruing a PBC. This analysis included all subjects that participated in the study that were not otherwise censored to more accurately count CVC-days." (NCT02593149)
Timeframe: Through the 13-month intervention period.
| Intervention | PBCs per 1,000 CVC-days (Number) |
|---|---|
| Treatment | 0.28 |
| Control | 0.75 |
10 trials available for 2-propanol and Catheter-Associated Infections
| Article | Year |
|---|---|
Needleless connector decontamination for prevention of central venous access device infection: A pilot randomized controlled trial.
Topics: 2-Propanol; Catheter-Related Infections; Catheterization, Central Venous; Chlorhexidine; Decontamina | 2021 |
2% chlorhexidine-70% isopropyl alcohol versus 10% povidone-iodine for insertion site cleaning before central line insertion in preterm infants: a randomised trial.
Topics: 2-Propanol; Anti-Infective Agents, Local; Catheter-Related Infections; Catheterization, Central Veno | 2018 |
Cluster-Randomized Trial of Devices to Prevent Catheter-Related Bloodstream Infection.
Topics: 2-Propanol; Aged; Antibiotic Prophylaxis; Bacteremia; Catheter-Related Infections; Central Venous Ca | 2018 |
Cost-effectiveness analysis of chlorhexidine-alcohol versus povidone iodine-alcohol solution in the prevention of intravascular-catheter-related bloodstream infections in France.
Topics: 2-Propanol; Alcohols; Bacteremia; Catheter-Related Infections; Chlorhexidine; Cost-Benefit Analysis; | 2018 |
Safety and efficacy of 2% chlorhexidine gluconate aqueous versus 2% chlorhexidine gluconate in 70% isopropyl alcohol for skin disinfection prior to percutaneous central venous catheter insertion in preterm neonates: the ARCTIC randomised-controlled feasib
Topics: 2-Propanol; Anti-Infective Agents, Local; Catheter-Related Infections; Catheterization, Central Veno | 2019 |
Comparison of four skin preparation strategies to prevent catheter-related infection in intensive care unit (CLEAN trial): a study protocol for a randomized controlled trial.
Topics: 2-Propanol; Administration, Cutaneous; Anti-Infective Agents, Local; Antisepsis; Bacteriological Tec | 2013 |
Scrubbing the hub of intravenous catheters with an alcohol wipe for 15 sec reduced neonatal sepsis.
Topics: 2-Propanol; Catheter-Related Infections; Catheterization, Central Venous; Central Venous Catheters; | 2015 |
What's new in catheter-related infection: skin cleansing and skin antisepsis.
Topics: 2-Propanol; Administration, Cutaneous; Anti-Infective Agents, Local; Antisepsis; Catheter-Related In | 2016 |
Is 2% chlorhexidine gluconate in 70% isopropyl alcohol more effective at preventing central venous catheter-related infections than routinely used chlorhexidine gluconate solutions: A pilot multicenter randomized trial (ISRCTN2657745)?
Topics: 2-Propanol; Adult; Aged; Aged, 80 and over; Ambulatory Care; Anti-Infective Agents, Local; Catheter- | 2016 |
Skin disinfection with octenidine dihydrochloride for central venous catheter site care: a double-blind, randomized, controlled trial.
Topics: 2-Propanol; Aged; Anti-Infective Agents, Local; Bacteremia; Catheter-Related Infections; Catheteriza | 2010 |
8 other studies available for 2-propanol and Catheter-Associated Infections
| Article | Year |
|---|---|
Leakage of isopropanol from port protectors used in neonatal care-Results from an in vitro study.
Topics: 2-Propanol; Catheter-Related Infections; Chromatography, Gas; Equipment Design; Humans; Infant Care; | 2020 |
The colonization rate of needleless connector and the impact of disinfection for 15 s on colonization: A prospective pre- and post-intervention study.
Topics: 2-Propanol; Bacterial Load; Catheter-Related Infections; Central Venous Catheters; Child; Child, Pre | 2019 |
A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit.
Topics: 2-Propanol; Catheter-Related Infections; Catheterization, Central Venous; Catheters, Indwelling; Cen | 2019 |
Chemical stability of heparin, isopropanol, and ethanol line lock solutions.
Topics: 2-Propanol; Catheter-Related Infections; Central Venous Catheters; Ethanol; Heparin; Humans; Solutio | 2015 |
Inhibition of heparin precipitation, bacterial growth, and fungal growth with a combined isopropanol-ethanol locking solution for vascular access devices.
Topics: 2-Propanol; Candida albicans; Catheter-Related Infections; Child; Escherichia coli; Ethanol; Heparin | 2015 |
A fall in bloodstream infections followed a change to 2% chlorhexidine in 70% isopropanol for catheter connection antisepsis: a pediatric single center before/after study on a hemopoietic stem cell transplant ward.
Topics: 2-Propanol; Anti-Infective Agents, Local; Antisepsis; Catheter-Related Infections; Catheters, Indwel | 2009 |
A multimodal approach to central venous catheter hub care can decrease catheter-related bloodstream infection.
Topics: 2-Propanol; Bacteremia; Catheter-Related Infections; Catheters, Indwelling; Chlorhexidine; Disinfect | 2010 |
Scrub the hub! Catheter needleless port decontamination.
Topics: 2-Propanol; Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Cross Infectio | 2011 |