Page last updated: 2024-10-29

2-propanol and Bacteremia

2-propanol has been researched along with Bacteremia in 15 studies

2-Propanol: An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
propan-2-ol : A secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group.

Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's4 (26.67)29.6817
2010's9 (60.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Shaheen, N1
Zeeshan, M1
Fasih, N1
Farooqi, J1
Jabeen, K1
Irfan, S1
Brunelli, SM1
Van Wyck, DB1
Njord, L1
Ziebol, RJ1
Lynch, LE1
Killion, DP1
Maunoury, F1
Farinetto, C1
Ruckly, S1
Guenezan, J1
Lucet, JC1
Lepape, A1
Pascal, J1
Souweine, B1
Mimoz, O1
Timsit, JF1
Yodoshi, T1
Ueda, S1
Goldman, RD1
Ausserhofer, D1
Fritz, E1
Them, C1
McDonald, C1
McGuane, S1
Thomas, J1
Hartley, S2
Robbins, S2
Roy, A3
Verlander, N2
Barbara, J1
Dettenkofer, M1
Wilson, C1
Gratwohl, A1
Schmoor, C1
Bertz, H1
Frei, R1
Heim, D1
Luft, D1
Schulz, S1
Widmer, AF1
Ramirez-Arcos, S1
Goldman, M1
Sannoh, S1
Clones, B1
Munoz, J1
Montecalvo, M1
Parvez, B1
Lockman, JL1
Heitmiller, ES1
Ascenzi, JA1
Berkowitz, I1
McDonald, CP2
Mahajan, P1
Smith, R1
Charlett, A1
Barbara, JA2
Brayer, C1
Micheau, P1
Bony, C1
Tauzin, L1
Pilorget, H1
Sampériz, S1
Alessandri, JL1
Lowe, P1
Harrison, JF1
Slopecki, A1
Chen, X1
Baumal, CR1
Kennedy, CJ1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Product Evaluation for the Effectiveness of the ClearGuard® HD End Cap[NCT02593149]1,902 participants (Actual)Interventional2015-11-30Completed
[NCT01629550]Phase 42,400 participants Interventional2012-10-31Completed
Skin Disinfection With Octenidine Dihydrochloride for the Prevention of Catheter-Associated Infections - A Double-Blind, Randomized, Controlled Trial[NCT00515151]Phase 4400 participants (Actual)Interventional2002-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Positive Blood Cultures (PBC's) Per 1,000 Central Venous Catheter (CVC)-Days

"This was calculated by dividing the cumulative number of PBCs by cumulative time at-risk as follows.~The National Healthcare Safety Network (NHSN) Center for Disease Control (CDC) 21-day outpatient hemodialysis patient rule is as follows: A PBC is considered a new event and counted only if it occurred 21 days or more after a previously reported PBC in the same patient; new PBC events are based on blood cultures drawn as an outpatient or within one calendar day after a hospital admission. Following a PBC additional same-type events were counted beginning 21 days following the initial event; the CVC-days were counted during this period. The CVC-days were calculated by summing the number of days each patient was at-risk of accruing a PBC. This analysis included all subjects that participated in the study that were not otherwise censored to more accurately count CVC-days." (NCT02593149)
Timeframe: Through the 13-month intervention period.

InterventionPBCs per 1,000 CVC-days (Number)
Treatment0.28
Control0.75

Reviews

1 review available for 2-propanol and Bacteremia

ArticleYear
[Care of the non-tunneled central venous catheter. Literature search on disinfectants, dressings and intervals between dressing changes].
    Pflege Zeitschrift, 2008, Volume: 61, Issue:8

    Topics: 2-Propanol; Bacteremia; Bacterial Infections; Bandages; Catheterization, Central Venous; Chlorhexidi

2008

Trials

5 trials available for 2-propanol and Bacteremia

ArticleYear
Cluster-Randomized Trial of Devices to Prevent Catheter-Related Bloodstream Infection.
    Journal of the American Society of Nephrology : JASN, 2018, Volume: 29, Issue:4

    Topics: 2-Propanol; Aged; Antibiotic Prophylaxis; Bacteremia; Catheter-Related Infections; Central Venous Ca

2018
Cost-effectiveness analysis of chlorhexidine-alcohol versus povidone iodine-alcohol solution in the prevention of intravascular-catheter-related bloodstream infections in France.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: 2-Propanol; Alcohols; Bacteremia; Catheter-Related Infections; Chlorhexidine; Cost-Benefit Analysis;

2018
A novel rapid and effective donor arm disinfection method.
    Transfusion, 2010, Volume: 50, Issue:1

    Topics: 2-Propanol; Anti-Infective Agents, Local; Bacteremia; Bacteria; Benchmarking; Blood Banking; Blood B

2010
Skin disinfection with octenidine dihydrochloride for central venous catheter site care: a double-blind, randomized, controlled trial.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2010, Volume: 16, Issue:6

    Topics: 2-Propanol; Aged; Anti-Infective Agents, Local; Bacteremia; Catheter-Related Infections; Catheteriza

2010
Skin disinfection methods: prospective evaluation and postimplementation results.
    Transfusion, 2010, Volume: 50, Issue:1

    Topics: 2-Propanol; Anti-Infective Agents, Local; Bacteremia; Bacteria; Blood Banking; Blood Banks; Blood Do

2010

Other Studies

9 other studies available for 2-propanol and Bacteremia

ArticleYear
Efforts to improve diagnosis of bacteraemia by reducing blood culture contamination in an emergency department: strategies and outcome.
    JPMA. The Journal of the Pakistan Medical Association, 2020, Volume: 70, Issue:5

    Topics: 2-Propanol; Anti-Infective Agents, Local; Bacteremia; Blood Culture; Blood Specimen Collection; Chlo

2020
Skin preparation for prevention of peripheral blood culture contamination in children.
    Pediatrics international : official journal of the Japan Pediatric Society, 2019, Volume: 61, Issue:7

    Topics: 2-Propanol; Anti-Infective Agents, Local; Antisepsis; Bacteremia; Blood Culture; Child; Child, Presc

2019
A multimodal approach to central venous catheter hub care can decrease catheter-related bloodstream infection.
    American journal of infection control, 2010, Volume: 38, Issue:6

    Topics: 2-Propanol; Bacteremia; Catheter-Related Infections; Catheters, Indwelling; Chlorhexidine; Disinfect

2010
Scrub the hub! Catheter needleless port decontamination.
    Anesthesiology, 2011, Volume: 114, Issue:4

    Topics: 2-Propanol; Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Cross Infectio

2011
Relative values of the interventions of diversion and improved donor-arm disinfection to reduce the bacterial risk from blood transfusion.
    Vox sanguinis, 2004, Volume: 86, Issue:3

    Topics: 2-Propanol; Arm; Bacteremia; Bacteriological Techniques; Blood; Blood Donors; Blood Specimen Collect

2004
[Neonatal accidental burn by isopropyl alcohol].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2004, Volume: 11, Issue:8

    Topics: 2-Propanol; Accidents, Home; Bacteremia; Burns, Chemical; Enterococcus faecalis; Fatal Outcome; Gram

2004
Evaluation of donor arm disinfection techniques.
    Vox sanguinis, 2001, Volume: 80, Issue:3

    Topics: 2-Propanol; Administration, Cutaneous; Arm; Bacteremia; Bacteria; Bacteriological Techniques; Blood

2001
Iris Abscess.
    The New England journal of medicine, 2018, Jan-11, Volume: 378, Issue:2

    Topics: Abscess; Adult; Bacteremia; Female; Humans; Iris; Iris Diseases; Staphylococcal Infections; Tomograp

2018
Sectorial iris infarction caused by meningococcal septicaemia.
    Australian and New Zealand journal of ophthalmology, 1995, Volume: 23, Issue:2

    Topics: Anti-Bacterial Agents; Bacteremia; Conjunctival Diseases; Disseminated Intravascular Coagulation; Ey

1995