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2-propanol and Alloxan Diabetes

2-propanol has been researched along with Alloxan Diabetes in 27 studies

2-Propanol: An isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
propan-2-ol : A secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"This study was aimed to evaluate the combined effect of curcumin with vitamin C supplementation on hyperglycemic and dyslipidemia conditions and endothelial cell dysfunction induced in diabetic rats."3.73Combined effects of curcumin and vitamin C to protect endothelial dysfunction in the iris tissue of STZ-induced diabetic rats. ( Bunnag, S; Futrakul, N; Jariyapongskul, A; Patumraj, S; Sridulyakul, P; Wongeakin, N, 2006)
" One group received no additional treatment whilst the other was given the aldose reductase inhibitor, sorbinil, by dietary admixture (approximate dose was 30 mg/day/kg body weight)."3.67Effects of sorbinil treatment in rats with chronic streptozotocin-diabetes; changes in lens and in substance P and catecholamines in the iris. ( Calcutt, NA; Clarke, HE; Compton, AM; Keen, P; Macdonald, IA; Tomlinson, DR; Willars, GB, 1989)
" Administration of ethanolic extract at a dosage of 0."1.36Antidiabetic and antihyperlipidemic activity of ethyl acetate:isopropanol (1:1) fraction of Vernonia anthelmintica seeds in streptozotocin induced diabetic rats. ( Babu, KR; Fatima, SS; Kumar, KV; Kumar, MT; Rajasekhar, MD; Rao, CA, 2010)
"In untreated galactose-fed rats a 4-fold increase in the mean permeability surface area product (PA) to sucrose at the BRB was observed when the aqueous humor was not frozen during retinal dissection."1.29Permeability of the blood-retinal and blood-aqueous barriers in galactose-fed rats. ( Caspers-Velu, LE; Kador, PF; Rapoport, SI; Wadhwani, KC, 1995)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199010 (37.04)18.7374
1990's8 (29.63)18.2507
2000's6 (22.22)29.6817
2010's2 (7.41)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Fatima, SS1
Rajasekhar, MD1
Kumar, KV1
Kumar, MT1
Babu, KR1
Rao, CA1
Tie, F1
Li, G1
Hu, N1
Li, J1
Wang, Z1
Wang, H1
Jin, M1
Liu, HD1
Zhang, YH1
Moravski, CJ2
Skinner, SL1
Stubbs, AJ1
Sarlos, S1
Kelly, DJ1
Cooper, ME1
Gilbert, RE1
Wilkinson-Berka, JL2
ENGERMAN, RL1
MEYER, RK1
BUESSELER, JA1
Bergman, PB1
Edmondson, SR1
Russo, VC1
Bach, LA1
Werther, GA1
Jariyapongskul, A3
Rungjaroen, T2
Kasetsuwan, N2
Pathumraj, S1
Niimi, H2
Patumraj, S2
Wongeakin, N1
Sridulyakul, P1
Futrakul, N1
Bunnag, S1
Sima, J1
Ma, J1
Zhang, SX1
Guo, J1
Seki, J1
Ishibashi, T1
Tanaka, K1
Taniguchi, Y1
Marfurt, CF1
Echtenkamp, SF1
Brewster, WJ2
Fernyhough, P2
Diemel, LT2
Mohiuddin, L1
Tomlinson, DR3
Li, H1
Grimes, P1
Caspers-Velu, LE2
Wadhwani, KC2
Rapoport, SI2
Kador, PF4
Vandertop, WP1
de Vries, WB1
Notermans, NC1
Tulleken, CA1
Gispen, WH1
Fernandes, K1
Fonteles, MC1
Matheny, JL1
Bito, LZ1
Cohen, G1
Allis, B1
Winston, B1
Mytilineou, C1
Heikkila, R1
Hellweg, R1
Wöhrle, M1
Hartung, HD1
Stracke, H1
Hock, C1
Federlin, K1
Crowe, R1
Burnstock, G1
Willars, GB1
Calcutt, NA1
Compton, AM1
Macdonald, IA1
Clarke, HE1
Keen, P1
Kinoshita, JH2
Terubayashi, H1
Akagi, Y1
Waitzman, MB1
Kojima, K1
Hasegawa, Y1
Hirata, K1

Reviews

2 reviews available for 2-propanol and Alloxan Diabetes

ArticleYear
The physiology and pathophysiology of intraocular fluids.
    Experimental eye research, 1977, Volume: 25 Suppl

    Topics: Amino Acids; Anesthesia, General; Animals; Aqueous Humor; Biological Transport; Cataract; Cats; Cili

1977
Possible new concepts relating prostaglandins to various ocular functions.
    Survey of ophthalmology, 1970, Volume: 14, Issue:4

    Topics: Animals; Blepharoptosis; Blood Coagulation; Capillary Permeability; Catecholamines; Diabetes Mellitu

1970

Other Studies

25 other studies available for 2-propanol and Alloxan Diabetes

ArticleYear
Antidiabetic and antihyperlipidemic activity of ethyl acetate:isopropanol (1:1) fraction of Vernonia anthelmintica seeds in streptozotocin induced diabetic rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:2

    Topics: 2-Propanol; Acetates; Animals; Blood Glucose; Chemical Fractionation; Chromatography, Gel; Diabetes

2010
Oligostilbenes extracts from Iris lactea Pall. var. chinensis (Fisch.) Koidz improve lipid metabolism in HFD/STZ-induced diabetic mice and inhibit adipogenesis in 3T3-L1 cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 131

    Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Diabetes Mellitus, Experimental; Diet, High-Fat; Do

2020
[Study on acting mechanism of shenqi yiqi drop pill for intervening irido-microangiopathy in diabetic rats].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2010, Volume: 30, Issue:2

    Topics: Animals; Capillary Permeability; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drugs,

2010
The renin-angiotensin system influences ocular endothelial cell proliferation in diabetes: transgenic and interventional studies.
    The American journal of pathology, 2003, Volume: 162, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Chronic Disease; D

2003
EFFECTS OF ALLOXAN DIABETES AND STEROID HYPERTENSION ON RETINAL VASCULATURE.
    American journal of ophthalmology, 1964, Volume: 58

    Topics: Animals; Choroid; Cortisone; Desoxycorticosterone; Diabetes Mellitus, Experimental; Diabetic Retinop

1964
Expression of the IGF system in normal and diabetic transgenic (mRen-2)27 rat eye.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:8

    Topics: Animals; Animals, Genetically Modified; Ciliary Body; Cornea; Diabetes Mellitus, Experimental; Diabe

2005
Chronic changes of the iris microvasculature of streptozotocin-induced diabetic rats using fluorescence videomicroscopy.
    Clinical hemorheology and microcirculation, 2006, Volume: 34, Issue:1-2

    Topics: Animals; Cell Adhesion; Chronic Disease; Diabetes Mellitus, Experimental; Diabetic Angiopathies; End

2006
Combined effects of curcumin and vitamin C to protect endothelial dysfunction in the iris tissue of STZ-induced diabetic rats.
    Clinical hemorheology and microcirculation, 2006, Volume: 35, Issue:4

    Topics: Animals; Ascorbic Acid; Blood Glucose; Curcumin; Diabetes Complications; Diabetes Mellitus, Experime

2006
Study of the influence of angiostatin intravitreal injection on vascular leakage in retina and iris of the experimental diabetic rats.
    Yan ke xue bao = Eye science, 2006, Volume: 22, Issue:4

    Topics: Angiostatins; Animals; Capillary Permeability; Diabetes Mellitus, Experimental; Diabetic Retinopathy

2006
Long-term effects of oral vitamin C supplementation on the endothelial dysfunction in the iris microvessels of diabetic rats.
    Microvascular research, 2007, Volume: 74, Issue:1

    Topics: Administration, Oral; Animals; Ascorbic Acid; Blood Glucose; Cell Adhesion; Diabetes Mellitus, Exper

2007
Disruption of iridial blood-aqueous barrier in experimental diabetic rats.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1982, Volume: 219, Issue:4

    Topics: Animals; Aqueous Humor; Diabetes Mellitus, Experimental; Humans; Iris; Male; Microscopy, Electron; R

1982
The effect of diabetes on neuropeptide content in the rat cornea and iris.
    Investigative ophthalmology & visual science, 1995, Volume: 36, Issue:6

    Topics: Animals; Calcitonin Gene-Related Peptide; Cornea; Diabetes Mellitus, Experimental; Diabetic Neuropat

1995
Changes in nerve growth factor and preprotachykinin messenger RNA levels in the iris and trigeminal ganglion in diabetic rats; effects of treatment with insulin or nerve growth factor.
    Brain research. Molecular brain research, 1995, Volume: 29, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; GAP-43 Protein; Insulin; Iris;

1995
Adrenergic innervation of the choroid and iris in diabetic rats.
    Current eye research, 1993, Volume: 12, Issue:1

    Topics: Adrenergic Fibers; Animals; Choroid; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Iris; M

1993
Permeability of the blood-retinal and blood-aqueous barriers in galactose-fed rats.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1995,Fall, Volume: 11, Issue:3

    Topics: Aldehyde Reductase; Animals; Autoradiography; Blood-Aqueous Barrier; Blood-Retinal Barrier; Capillar

1995
Neural influences on the iris of diabetic rats and effect of oculomotor nerve crush.
    Journal of the autonomic nervous system, 1995, Oct-05, Volume: 55, Issue:1-2

    Topics: Animals; Cholinergic Fibers; Dark Adaptation; Diabetes Mellitus, Experimental; Female; Iris; Nerve C

1995
Stimulation of nerve growth-factor and substance P expression in the iris-trigeminal axis of diabetic rats--involvement of oxidative stress and effects of aldose reductase inhibition.
    Brain research, 1998, Aug-17, Volume: 802, Issue:1-2

    Topics: Aldehyde Reductase; Animals; Blood Glucose; Carrier Proteins; Diabetes Mellitus, Experimental; Enzym

1998
Iris vasculopathy in galactose-fed rats.
    Experimental eye research, 1999, Volume: 68, Issue:2

    Topics: Aldehyde Reductase; Animals; Blood Vessels; Blood-Aqueous Barrier; Diabetes Mellitus, Experimental;

1999
alpha-Adrenoceptor alteration by alloxan diabetes in iris dilator muscle of the rabbit.
    Experientia, 1979, May-15, Volume: 35, Issue:5

    Topics: Animals; Diabetes Mellitus, Experimental; In Vitro Techniques; Iris; Muscle Contraction; Muscle, Smo

1979
Prevention of 6-hydroxydopamine neurotoxicity.
    European journal of pharmacology, 1975, Volume: 33, Issue:1

    Topics: Animals; Diabetes Mellitus, Experimental; Heart Atria; Hydroxydopamines; Iris; Male; Mice; Nerve End

1975
Diabetes mellitus-associated decrease in nerve growth factor levels is reversed by allogeneic pancreatic islet transplantation.
    Neuroscience letters, 1991, Apr-15, Volume: 125, Issue:1

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Ganglia, Spinal; Glycated Hemoglobin; Heart

1991
An increase of vasoactive intestinal polypeptide-, but not neuropeptide Y-, substance P- or catecholamine-containing nerves in the iris of the streptozotocin-induced diabetic rat.
    Experimental eye research, 1988, Volume: 47, Issue:5

    Topics: Adrenergic Fibers; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Iris; Male; Nerv

1988
Effects of sorbinil treatment in rats with chronic streptozotocin-diabetes; changes in lens and in substance P and catecholamines in the iris.
    Current eye research, 1989, Volume: 8, Issue:4

    Topics: Animals; Blood Glucose; Body Weight; Catecholamines; Diabetes Mellitus, Experimental; Epinephrine; I

1989
[Diabetic changes in pupillary reactions and iris histology. No. 3. The role of aldose reductase inhibitor to iridal vessel hyperpermeability of galactose-fed rats].
    Nippon Ganka Gakkai zasshi, 1988, Volume: 92, Issue:10

    Topics: Aldehyde Reductase; Animals; Capillary Permeability; Diabetes Mellitus, Experimental; Galactose; Hor

1988
[Electron microscopic findings of the ocular tissues in alloxan rats. II. On the iris and ciliary body (on the vessels of the iris and ciliary body)].
    Nihon ganka kiyo, 1972, Volume: 23, Issue:3

    Topics: Animals; Arteries; Capillaries; Ciliary Body; Diabetes Mellitus, Experimental; Erythrocytes; Iris; M

1972