2-piperidone has been researched along with Lung Neoplasms in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.79) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 12 (63.16) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Almaliti, J; Canuto, KM; Duggan, BM; Gerwick, WH; Glukhov, E; Keller, L; Koehnke, J; Liu, C; Luesch, H; Luo, D; Naman, CB; O'Donoghue, AJ; Sikandar, A; Suzuki, BM | 1 |
| Chen, L; Jiang, C; Li, Q; Lin, X; Wu, J; Wu, X; Xie, J; Xu, H; Zhang, H; Zheng, Z | 1 |
| Awasthi, V; Sahoo, K; Yadav, VR | 1 |
| Ben, W; Dong, L; Guan, Y; Huang, Y; Lu, M; Ning, N; Wang, Y; Yang, Y; Yuan, J; Zhang, D | 1 |
| Cai, Z; Chen, M; He, F; Liang, G; Shi, L; Wei, X; Wu, J; Xu, RA; Ying, S; Zhang, X | 1 |
| Huang, L; Li, W; Liang, G; Qiu, P; Ren, J; Shi, L; Wang, J; Wu, J; Wu, S; Wu, X; Yao, S; Yun, D; Zhang, S | 1 |
| Khrustalev, VN; Leonova, ES; Makarov, MV; Odinets, IL; Rybalkina, EY; Timofeeva, TV; Tongwa, P | 1 |
| Chen, L; Huang, XY; Jakoncic, J; Yang, S; Zhang, JJ | 1 |
| Du, Y; Fu, H; Khuri, FR; Li, Z; Liotta, D; Lou, B; Purcell, J; Snyder, JP; Thomas, SL; Zhao, J | 1 |
| Anant, S; Awasthi, V; Lagisetty, P; Sahoo, K; Vilekar, P | 1 |
| Anant, S; Awasthi, V; Dozmorov, MG; Sahoo, K | 1 |
| Agashe, H; Awasthi, V; Lagisetty, P; Sahoo, K | 1 |
| Danishefsky, SJ; Downey, R; Lecomte, N; Moore, MA; Nagorny, P; Njardarson, JT; Ouerfelli, O; Yang, G | 1 |
| Matono, K; Ogata, Y; Shirouzu, K | 1 |
| Chen, L; Danishefsky, SJ; Gaul, C; Huang, XY; Ma, X; Njardarson, JT; Shan, D | 1 |
| Imoto, M; Kawatani, M; Naganawa, H; Nakae, K; Takahashi, Y; Takemoto, Y | 1 |
| Fireman, BH; Friedman, GD; Selby, JV | 1 |
| Eriguchi, N; Hara, H; Ikeda, I; Inoue, S; Nakayama, T; Nishida, H; Ohishi, K; Tsuda, H; Yoshida, H | 1 |
| Burzynski, B; Burzynski, SR; Kampalath, BN; Liau, MC | 1 |
19 other study(ies) available for 2-piperidone and Lung Neoplasms
| Article | Year |
|---|---|
Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties.
Topics: Amino Acids; Aminobutyrates; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Cyanobacteria; Depsipeptides; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Lung Neoplasms; Models, Molecular; Molecular Structure; Pancreatic Elastase; Peptides, Cyclic; Piperidones; Protein Binding; Tandem Mass Spectrometry; Vinyl Chloride | 2020 |
Design and optimize N-substituted EF24 as effective and low toxicity NF-κB inhibitor for lung cancer therapy via apoptosis-to-pyroptosis switch.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzylidene Compounds; Cell Line, Tumor; Cell Survival; Drug Design; G2 Phase Cell Cycle Checkpoints; Humans; Lung Neoplasms; M Phase Cell Cycle Checkpoints; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Nitrogen; Piperidones; Pyroptosis; Xenograft Model Antitumor Assays | 2019 |
Preclinical evaluation of 4-[3,5-bis(2-chlorobenzylidene)-4-oxo-piperidine-1-yl]-4-oxo-2-butenoic acid, in a mouse model of lung cancer xenograft.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Benzylidene Compounds; Cell Line, Tumor; Dose-Response Relationship, Drug; Fluorodeoxyglucose F18; Gene Expression Regulation, Neoplastic; Humans; Inflammation Mediators; Ki-67 Antigen; Lung Neoplasms; Male; Mice; Mice, Nude; Multimodal Imaging; Phosphorylation; Piperidones; Positron-Emission Tomography; Signal Transduction; Time Factors; Tomography, X-Ray Computed; Transcription Factor RelA; Transfection; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Therapeutic role of EF24 targeting glucose transporter 1-mediated metabolism and metastasis in ovarian cancer cells.
Topics: Animals; Benzylidene Compounds; Biological Transport; Cell Line, Tumor; Cell Movement; Cell Proliferation; Energy Metabolism; Female; Glucose; Glucose Transporter Type 1; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Transplantation; Ovarian Neoplasms; Peritoneal Neoplasms; Piperidones | 2013 |
Anti-Lung Cancer Activity of the Curcumin Analog JZ534 In Vitro.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Curcumin; G2 Phase Cell Cycle Checkpoints; Humans; Lung Neoplasms; Piperidones | 2015 |
Design, synthesis, and evaluation of asymmetric EF24 analogues as potential anti-cancer agents for lung cancer.
Topics: Antineoplastic Agents; Apoptosis; Benzylidene Compounds; Cell Line, Tumor; Drug Design; Humans; Lung; Lung Neoplasms; Mitochondria; NF-kappa B; Piperidones; Reactive Oxygen Species; Signal Transduction | 2017 |
Synthesis, characterization and structure-activity relationship of novel N-phosphorylated E,E-3,5-bis(thienylidene)piperid-4-ones.
Topics: Antineoplastic Agents; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Female; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Nitrogen; Ovarian Neoplasms; Phosphorylation; Piperidones; Structure-Activity Relationship; Thiophenes | 2010 |
Migrastatin analogues target fascin to block tumour metastasis.
Topics: Actins; Animals; Antineoplastic Agents; Binding Sites; Breast Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Movement; Crystallography, X-Ray; Drug Resistance, Neoplasm; Female; Humans; Lung Neoplasms; Macrolides; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Microfilament Proteins; Models, Molecular; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Piperidones; Protein Conformation | 2010 |
Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy.
Topics: Antineoplastic Agents; Apoptosis; Benzylidene Compounds; Cell Line, Tumor; Drug Therapy, Combination; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Piperidones; Pyridines | 2010 |
CLEFMA-an anti-proliferative curcuminoid from structure-activity relationship studies on 3,5-bis(benzylidene)-4-piperidones.
Topics: Adenocarcinoma; Antineoplastic Agents; Autophagy; Benzylidene Compounds; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Piperidones; Structure-Activity Relationship | 2010 |
The curcuminoid CLEFMA selectively induces cell death in H441 lung adenocarcinoma cells via oxidative stress.
Topics: Active Transport, Cell Nucleus; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; Antioxidants; Benzylidene Compounds; Blotting, Western; Cell Death; Cell Line, Tumor; Cell Proliferation; Curcumin; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Lung Neoplasms; NF-E2-Related Factor 2; Oligonucleotide Array Sequence Analysis; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Piperidones; Reactive Oxygen Species; Time Factors | 2012 |
Cyclodextrin-mediated entrapment of curcuminoid 4-[3,5-bis(2-chlorobenzylidene-4-oxo-piperidine-1-yl)-4-oxo-2-butenoic acid] or CLEFMA in liposomes for treatment of xenograft lung tumor in rats.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Cyclodextrins; Disease Models, Animal; Drug Delivery Systems; Liposomes; Lung Neoplasms; Piperidones; Rats | 2011 |
Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin.
Topics: Animals; Cell Line, Tumor; Cell Movement; Ethers; Humans; Lung Neoplasms; Macrolides; Male; Mice; Neoplasm Metastasis; Piperidones; Small Cell Lung Carcinoma; Xenograft Model Antitumor Assays | 2011 |
[Anti-proliferative effects of biochemical defense modifier antineoplaston in colorectal carcinoma].
Topics: Animals; Apoptosis; Benzeneacetamides; Cell Cycle; Cell Cycle Proteins; Colorectal Neoplasms; Depression, Chemical; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Glutamine; Humans; Lung Neoplasms; Mice; Mice, Nude; Phenylacetates; Piperidones; Tumor Cells, Cultured | 2003 |
Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Humans; Lactones; Lung Neoplasms; Macrolides; Mice; Neoplasm Metastasis; Piperidones; rac GTP-Binding Proteins | 2005 |
Migrastatin, a novel 14-membered ring macrolide, inhibits anchorage-independent growth of human small cell lung carcinoma Ms-1 cells.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Small Cell; Humans; Lactones; Lung Neoplasms; Macrolides; Mice; Piperidones; Rats; Tumor Cells, Cultured | 2001 |
Screening prescription drugs for possible carcinogenicity: eleven to fifteen years of follow-up.
Topics: Anti-Bacterial Agents; Atropa belladonna; Carcinogens; Drug-Related Side Effects and Adverse Reactions; Erythromycin; Esophageal Neoplasms; Folic Acid; Follow-Up Studies; Gastrointestinal Neoplasms; Lung Neoplasms; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neomycin; Neoplasms; Phenylbutazone; Piperidones; Plants, Medicinal; Plants, Toxic; Polymyxin B; Propantheline; Secobarbital; Sulfathiazoles; Vitamins | 1989 |
Chemopreventive effect of antineoplaston A-10 on urethane-induced pulmonary neoplasm in mice.
Topics: Adenoma; Animals; Benzeneacetamides; Female; Lung Neoplasms; Mice; Piperidines; Piperidones; Urethane | 1988 |
Chemoprevention by antineoplaston A10 of benzo(a)pyrene-induced pulmonary neoplasia.
Topics: Adenoma; Animals; Antineoplastic Agents; Benzeneacetamides; Benzo(a)pyrene; Body Weight; Female; Lung Neoplasms; Mice; Mice, Inbred A; Piperidines; Piperidones | 1987 |