2-piperidone has been researched along with Liver Neoplasms in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 7 (43.75) | 24.3611 |
| 2020's | 4 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Hoffmann, M; Li, Y; Liu, L; MacGorman, K; Palmisano, M; Zhou, S | 1 |
| Cheng, X; Tian, P; Yan, X; Zheng, W | 1 |
| Gao, ZF; Hou, GG; Meng, QG; Sun, Y; Wang, CH; Xin, WY; Yan, WB; Yao, BR | 1 |
| Cong, W; Gao, ZF; Hou, GG; Sun, Y; Sun, YF; Wang, CH; Yan, WB; Zhang, JJ; Zhang, YL | 1 |
| Chen, X; Ding, Y; Ge, J; Wang, B; Yu, B | 1 |
| Chen, M; Fan, X; Ji, J; Lu, C; Song, J; Tu, J; Weng, Q; Wu, F; Xu, M; Zhang, D; Zhao, Z; Zheng, L | 1 |
| Chen, X; Li, W; Shang, SQ; Shen, HQ; Zhao, XL | 1 |
| Akagi, Y; Matono, K; Ogata, Y; Shirouzu, K; Tsuda, H; Uchida, S; Ushijima, M | 1 |
| Jin, X; Jin, Y; Li, X; Tin, L; Wu, Y; Zhang, F; Zhang, Y; Zhao, R | 1 |
| Hou, L; Jiang, H; Liang, Y; Liu, L; Lu, Z; Meng, X; Pan, S; Song, X; Wang, J; Yin, D; Zheng, T | 1 |
| Fang, X; Jiang, H; Liang, Y; Liu, H; Liu, J; Liu, L; Meng, X; Song, R; Tian, L; Wang, J; Wang, L; Yin, D; Zheng, T | 1 |
| Akagi, Y; Araki, Y; Hara, H; Kumabe, T; Matono, K; Ogata, Y; Saitsu, H; Sata, M; Shirouzu, K; Tsuda, H | 1 |
| Hara, H; Iemura, A; Sata, M; Tsuda, H; Uchida, M; Yamana, K | 1 |
| Milushev, A; Stoichkov, I; Todorov, D | 1 |
| Lijinsky, W; Taylor, HW | 1 |
| Tsuda, H | 1 |
2 trial(s) available for 2-piperidone and Liver Neoplasms
| Article | Year |
|---|---|
Single-Dose Pharmacokinetics, Safety, and Tolerability of Avadomide (CC-122) in Subjects With Mild, Moderate, or Severe Renal Impairment.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Carcinoma, Hepatocellular; Case-Control Studies; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; Genetic Pleiotropy; Glioblastoma; Hematologic Neoplasms; Humans; Liver Neoplasms; Male; Middle Aged; Piperidones; Quinazolinones; Renal Insufficiency; Safety; Severity of Illness Index; Ubiquitin-Protein Ligases | 2020 |
Randomized phase II study of 5-fluorouracil hepatic arterial infusion with or without antineoplastons as an adjuvant therapy after hepatectomy for liver metastases from colorectal cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Combinations; Fluorouracil; Glutamine; Hepatectomy; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Middle Aged; Phenylacetates; Piperidones; Survival Analysis; Treatment Outcome | 2015 |
14 other study(ies) available for 2-piperidone and Liver Neoplasms
| Article | Year |
|---|---|
Piplartine attenuates the proliferation of hepatocellular carcinoma cells via regulating hsa_circ_100338 expression.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Piperidones; RNA, Circular; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2020 |
Discovery of novel NF-кB inhibitor based on scaffold hopping: 1,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidine.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line; Dose-Response Relationship, Drug; Drug Design; Humans; Inflammation; Lipopolysaccharides; Liver Neoplasms; MAP Kinase Signaling System; Mice; Molecular Docking Simulation; NF-kappa B; Phosphorylation; Piperidones; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2020 |
Trifluoromethyl-substituted 3,5-bis(arylidene)-4-piperidones as potential anti-hepatoma and anti-inflammation agents by inhibiting NF-кB activation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lipopolysaccharides; Liver Neoplasms; Molecular Docking Simulation; Molecular Structure; NF-kappa B; Phosphorylation; Piperidones; Structure-Activity Relationship | 2021 |
Deubiquitinase inhibitor b-AP15 activates endoplasmic reticulum (ER) stress and inhibits Wnt/Notch1 signaling pathway leading to the reduction of cell survival in hepatocellular carcinoma cells.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Survival; Deubiquitinating Enzymes; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Hep G2 Cells; Humans; Liver Neoplasms; Piperidones; Receptor, Notch1; Unfolded Protein Response; Wnt Signaling Pathway | 2018 |
Piplartine suppresses proliferation and invasion of hepatocellular carcinoma by LINC01391-modulated Wnt/β-catenin pathway inactivation through ICAT.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Mice, Nude; Neoplasm Invasiveness; Piperidones; RNA, Long Noncoding; Tumor Burden; Wnt Signaling Pathway; Xenograft Model Antitumor Assays | 2019 |
Dual Inhibition of Cdc7 and Cdk9 by PHA-767491 Suppresses Hepatocarcinoma Synergistically with 5-Fluorouracil.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Line, Tumor; Checkpoint Kinase 1; Cyclin-Dependent Kinase 9; Female; Fluorouracil; Humans; Liver Neoplasms; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; Myeloid Cell Leukemia Sequence 1 Protein; Phosphorylation; Piperidones; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Pyrroles; Xenograft Model Antitumor Assays | 2015 |
EF24 Suppresses Invasion and Migration of Hepatocellular Carcinoma Cells
Topics: Benzylidene Compounds; Carcinoma, Hepatocellular; Cell Movement; Hep G2 Cells; Humans; Liver Neoplasms; Neoplasm Invasiveness; Phosphorylation; Piperidones; Proto-Oncogene Proteins pp60(c-src) | 2016 |
Diphenyl difluoroketone: a potent chemotherapy candidate for human hepatocellular carcinoma.
Topics: Animals; Apoptosis; Benzylidene Compounds; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin B1; Cyclooxygenase 2; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Mice, Nude; NF-kappa B; Piperidones; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Xenograft Model Antitumor Assays | 2011 |
Hypoxia-mediated sorafenib resistance can be overcome by EF24 through Von Hippel-Lindau tumor suppressor-dependent HIF-1α inhibition in hepatocellular carcinoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzylidene Compounds; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Resistance, Neoplasm; Drug Therapy, Combination; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Niacinamide; Phenylurea Compounds; Piperidones; Sorafenib; Treatment Outcome; Von Hippel-Lindau Tumor Suppressor Protein; Xenograft Model Antitumor Assays | 2013 |
Long-term survival following treatment with antineoplastons for colon cancer with unresectable multiple liver metastases: report of a case.
Topics: Adenocarcinoma; Aged; Benzeneacetamides; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Electrocoagulation; Humans; Liver Neoplasms; Male; Microwaves; Piperidones; Prognosis; Survivors | 2003 |
Inhibitory effect of antineoplaston A10 and AS2-1 on human hepatocellular carcinoma.
Topics: Antineoplastic Agents; Benzeneacetamides; Carcinoma, Hepatocellular; Drug Combinations; Glutamine; Humans; Liver Neoplasms; Phenylacetates; Piperidones; Tumor Cells, Cultured | 1996 |
[Experiment to potentiate the effect of cyclophosphamide combined with tempidon and caffeine in leukemia L1210 and Lewis hepatic carcinoma].
Topics: Animals; Caffeine; Carcinoma; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Female; Leukemia L1210; Liver Neoplasms; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Piperidines; Piperidones; Psychotropic Drugs; Tosyl Compounds; Triacetoneamine-N-Oxyl | 1978 |
Tumorigenesis by oxygenated nitrosopiperidines in rats.
Topics: Animals; Esophageal Neoplasms; Liver Neoplasms; Neoplasms, Experimental; Nitroso Compounds; Nose Neoplasms; Piperidines; Piperidones; Rats; Sex Factors | 1975 |
Inhibitory effect of antineoplaston A-10 on breast cancer transplanted to athymic mice and human hepatocellular carcinoma cell lines. The members of Antineoplaston Study Group.
Topics: Administration, Oral; Animals; Benzeneacetamides; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Piperidines; Piperidones; Transplantation, Heterologous; Tumor Cells, Cultured | 1990 |