Page last updated: 2024-08-21

2-piperidone and Libman-Sacks Disease

2-piperidone has been researched along with Libman-Sacks Disease in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (42.86)	24.3611
2020's	4 (57.14)	2.80

Authors

Authors	Studies
Delev, N; Furie, RA; Gaudy, A; Hough, DR; Korish, S; Schafer, PH; Weiswasser, M; Werth, VP; Ye, Y; Zhan, X	1
Agafonova, N; Delev, N; Dörner, T; Furie, R; Gaudy, A; Irazoque-Palazuelos, F; Korish, S; Liu, Z; Majdan, M; Merrill, JT; Petronijevic, M; Schafer, PH; van Vollenhoven, R; Velasco, J; Weiswasser, M; Werth, VP; Ye, Y	1
Mucke, J	1
Handa, H; Ito, T	1
Atsriku, C; Gaudy, A; Liu, L; MacGorman, K; Palmisano, M; Surapaneni, S; Xue, Y; Ye, Y	1
Capone, L; Hur, EM; Kosek, J; Nakayama, Y; Ringheim, GE; Schafer, PH	1
Chopra, R; Kosek, J; Liu, L; Palmisano, M; Ringheim, G; Schafer, PH; Thomas, M; Wu, L; Yang, Z; Ye, Y	1

Reviews

1 review(s) available for 2-piperidone and Libman-Sacks Disease

Article	Year
[Cereblon as a primary target of IMiDs]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 2019, Volume: 60, Issue:9 Topics: Adaptor Proteins, Signal Transducing; Heterocyclic Compounds, 4 or More Rings; Humans; Immunomodulation; Lupus Erythematosus, Systemic; Lymphoma, Large B-Cell, Diffuse; Morpholines; Peptide Hydrolases; Phthalimides; Piperidones; Protease Inhibitors; Substrate Specificity; Ubiquitin-Protein Ligases	2019

Article

Year

[Cereblon as a primary target of IMiDs].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 2019, Volume: 60, Issue:9

Topics: Adaptor Proteins, Signal Transducing; Heterocyclic Compounds, 4 or More Rings; Humans; Immunomodulation; Lupus Erythematosus, Systemic; Lymphoma, Large B-Cell, Diffuse; Morpholines; Peptide Hydrolases; Phthalimides; Piperidones; Protease Inhibitors; Substrate Specificity; Ubiquitin-Protein Ligases

2019

Trials

4 trial(s) available for 2-piperidone and Libman-Sacks Disease

Article	Year
Iberdomide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled, ascending-dose, phase 2a study. Lupus science & medicine, 2022, Volume: 9, Issue:1 Topics: Dose-Response Relationship, Drug; Humans; Lupus Erythematosus, Systemic; Morpholines; Phthalimides; Piperidones	2022
Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus. The New England journal of medicine, 2022, 03-17, Volume: 386, Issue:11 Topics: Adaptor Proteins, Signal Transducing; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Ikaros Transcription Factor; Lupus Erythematosus, Systemic; Male; Middle Aged; Morpholines; Phthalimides; Piperidones; Severity of Illness Index; Ubiquitin-Protein Ligases	2022
Evaluation of iberdomide and cytochrome p450 drug-drug interaction potential in vitro and in a phase 1 study in healthy subjects. European journal of clinical pharmacology, 2021, Volume: 77, Issue:2 Topics: Adult; Area Under Curve; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Healthy Volunteers; Heterocyclic Compounds, 4 or More Rings; Humans; Immunologic Factors; Itraconazole; Lupus Erythematosus, Systemic; Male; Microsomes, Liver; Middle Aged; Morpholines; Multiple Myeloma; Phthalimides; Piperidones; Rifampin; Young Adult	2021
Cereblon modulator iberdomide induces degradation of the transcription factors Ikaros and Aiolos: immunomodulation in healthy volunteers and relevance to systemic lupus erythematosus. Annals of the rheumatic diseases, 2018, Volume: 77, Issue:10 Topics: Adaptor Proteins, Signal Transducing; Autoantibodies; Blotting, Western; Double-Blind Method; Flow Cytometry; Healthy Volunteers; Heterocyclic Compounds, 4 or More Rings; Humans; Ikaros Transcription Factor; Immunomodulation; Leukocytes, Mononuclear; Lupus Erythematosus, Systemic; Morpholines; Peptide Hydrolases; Phthalimides; Piperidones; RNA, Messenger; Ubiquitin-Protein Ligases	2018

Other Studies

2 other study(ies) available for 2-piperidone and Libman-Sacks Disease

Article	Year
[Iberdomide against Aiolos and Ikaros in systemic lupus erythematosus]. Zeitschrift fur Rheumatologie, 2022, Volume: 81, Issue:7 Topics: Humans; Lupus Erythematosus, Systemic; Morpholines; Phthalimides; Piperidones	2022
Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity. Journal of immunology (Baltimore, Md. : 1950), 2017, 10-01, Volume: 199, Issue:7 Topics: Adaptor Proteins, Signal Transducing; Antibody Formation; B-Cell Activating Factor; B-Lymphocyte Subsets; CD40 Ligand; Cell Differentiation; Heterocyclic Compounds, 4 or More Rings; Humans; Ikaros Transcription Factor; Immunologic Memory; Interleukin-2; Interleukins; Lupus Erythematosus, Systemic; Morpholines; Peptide Hydrolases; Phthalimides; Piperidones; Tumor Necrosis Factor Receptor Superfamily, Member 7; Ubiquitin-Protein Ligases	2017

Article

Year

[Iberdomide against Aiolos and Ikaros in systemic lupus erythematosus].

Zeitschrift fur Rheumatologie, 2022, Volume: 81, Issue:7

Topics: Humans; Lupus Erythematosus, Systemic; Morpholines; Phthalimides; Piperidones

2022

Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity.

Journal of immunology (Baltimore, Md. : 1950), 2017, 10-01, Volume: 199, Issue:7

Topics: Adaptor Proteins, Signal Transducing; Antibody Formation; B-Cell Activating Factor; B-Lymphocyte Subsets; CD40 Ligand; Cell Differentiation; Heterocyclic Compounds, 4 or More Rings; Humans; Ikaros Transcription Factor; Immunologic Memory; Interleukin-2; Interleukins; Lupus Erythematosus, Systemic; Morpholines; Peptide Hydrolases; Phthalimides; Piperidones; Tumor Necrosis Factor Receptor Superfamily, Member 7; Ubiquitin-Protein Ligases

2017