2-piperidone has been researched along with Leukemia, Myeloid, Acute in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carmichael, J; Cathers, B; Chamberlain, P; Clayton, T; Contreras, A; Dick, JE; Fan, J; Fontanillo, C; Hansen, J; Hsu, C; Jang, IS; Jin, L; Lopez-Girona, A; Lu, CC; Lu, G; Matyskiela, M; Mbong, N; Mendy, D; Minden, MD; Ng, SWK; Pierce, DW; Pourdehnad, M; Rolfe, M; Rychak, E; Surka, C; Tindall, E; Tran, E; Wang, JCY; Wang, K | 1 |
| Alexander, M; Ammirante, M; Cathers, BE; Correa, M; Hansen, JD; Huang, D; LeBrun, LA; Lopez-Girona, A; Lu, G; Nagy, M; Narla, RK; Piccotti, JR; Pourdehnad, M; Sapienza, J; Tang, Y; Zhang, W | 1 |
| Anderson, AA; Becker, PS; Erba, HP; Flesher, DL; Grunwald, MR; Henary, HA; Rasmussen, E; Shami, PJ; Wang, ES; Zhu, M | 1 |
| Koeffler, HP | 1 |
1 review(s) available for 2-piperidone and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications.
Topics: 3-Deazauridine; Acetamides; Alkaloids; Animals; Calcitriol; Cell Differentiation; Cell Line; Cells, Cultured; Dimethyl Sulfoxide; Glycoproteins; Granulocytes; Growth Inhibitors; Humans; Hypoxanthines; Interferons; Interleukin-6; Leukemia Inhibitory Factor; Leukemia, Myeloid, Acute; Lymphokines; Lyngbya Toxins; Macrophages; Mice; Phorbol Esters; Piperidones; Polyethylene Glycols; Tretinoin | 1983 |
1 trial(s) available for 2-piperidone and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Phase 1b study of the MDM2 inhibitor AMG 232 with or without trametinib in relapsed/refractory acute myeloid leukemia.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Molecular Targeted Therapy; Piperidones; Proto-Oncogene Proteins c-mdm2; Pyridones; Pyrimidinones; Recurrence; Treatment Outcome | 2019 |
2 other study(ies) available for 2-piperidone and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells.
Topics: Acetamides; Adaptor Proteins, Signal Transducing; Animals; Cell Line, Tumor; CRISPR-Cas Systems; Humans; Isoindoles; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Models, Molecular; Molecular Targeted Therapy; Neoplasm Proteins; Neoplastic Stem Cells; Nuclear Factor 45 Protein; Nuclear Factor 90 Proteins; Peptide Termination Factors; Piperidones; Proteasome Endopeptidase Complex; Protein Conformation; Protein Processing, Post-Translational; Proteolysis; Small Molecule Libraries; Stress, Physiological; TOR Serine-Threonine Kinases; U937 Cells; Ubiquitin-Protein Ligases; Ubiquitination; Xenograft Model Antitumor Assays | 2021 |
CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia.
Topics: Acetamides; Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Isoindoles; Leukemia, Myeloid, Acute; Macaca fascicularis; Male; Mice; Molecular Structure; Peptide Termination Factors; Piperidones; Proteolysis; Structure-Activity Relationship; Ubiquitin-Protein Ligases | 2021 |