2-piperidone has been researched along with Inflammation in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 6 (35.29) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Jiang, FC; Li, L | 1 |
| Choi, SE; Han, SJ; Heo, YJ; Jeon, JY; Kang, Y; Kim, DJ; Kim, HJ; Lee, KW; Lee, N | 1 |
| Choudhury, AR; Farkas, ME; Golakoti, NR; Joshi, BP; Joshi, M; Kar, S; Kumar Rokkam, S; Mas-Rosario, JA | 1 |
| Hou, G; Li, C; Li, W; Liu, Y; Yan, W | 1 |
| Griñán-Ferré, C; Leiva, R; Pallàs, M; Puigoriol-Illamola, D; Vázquez, S; Vázquez-Carrera, M | 1 |
| Gao, ZF; Hou, GG; Meng, QG; Sun, Y; Wang, CH; Xin, WY; Yan, WB; Yao, BR | 1 |
| Barbosa-Filho, JM; Bezerra, DP; Contessoto, NSA; Cornélio, ML; da Silveira, NJF; Girol, AP; Henrique, T; Oliani, SM; Silveira, ER; Stefanini, ACB; Tajara, EH; Zanon, CF | 1 |
| Ihm, CG; Jeong, KH; Kim, DR; Kim, JS; Kim, YG; Lee, SH; Lee, SY; Lee, TW; Moon, JY | 1 |
| Griñán-Ferré, C; Leiva, R; Pallàs, M; Puigoriol-Illamola, D; Vasilopoulou, F; Vázquez, S | 1 |
| Choi, YK; Jung, GS; Jung, YA; Lee, IK; Lee, S; Park, KG; Park, M; Seo, JB; Woo, HI | 1 |
| Cai, Y; Chen, X; Liang, G; Pan, Z; Tang, Q; Wang, J; Weng, B; Wu, J; Yang, S; Zhang, Y | 1 |
| Baik, SH; Choi, DS; Choi, HY; Choi, KM; Hong, HC; Hwang, HJ; Jung, TW; Kim, NH; Kim, SG; Ryu, JY; Seo, JA; Yoo, HJ | 1 |
| Czarnik, AW; DeWitt, SH; Jacques, V; Judge, TM; Van der Ploeg, LH | 1 |
| Choi, SH; Lee, CK; Lee, IK; Leem, J; Park, KG; Park, S | 1 |
| Grainger, DJ; Reckless, J | 1 |
| Umezawa, K | 1 |
| Luo, W; Shi, Z; Xiu, Q; Yan, Z; Ye, Y; Zhu, Q | 1 |
2 review(s) available for 2-piperidone and Inflammation
| Article | Year |
|---|---|
Broad-spectrum chemokine inhibitors (BSCIs) and their anti-inflammatory effects in vivo.
Topics: Animals; Anti-Inflammatory Agents; Cell Movement; Chemokine CCL2; Chemokines; Conserved Sequence; Disease Models, Animal; Humans; Inflammation; Peptides; Piperidones; Structure-Activity Relationship | 2003 |
[Screening of bioactive metabolites that suppress inflammation].
Topics: Animals; Anti-Inflammatory Agents; Benzamides; Biological Products; Cell Differentiation; Cyclohexanones; Depsipeptides; Drug Design; Drug Evaluation, Preclinical; Inflammation; Inflammation Mediators; Lipopolysaccharides; Neoplasms; NF-kappa B; Osteoclasts; Piperidones; Signal Transduction | 2007 |
15 other study(ies) available for 2-piperidone and Inflammation
| Article | Year |
|---|---|
Design, synthesis, and evaluation of 2-piperidone derivatives for the inhibition of β-amyloid aggregation and inflammation mediated neurotoxicity.
Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Death; Cell Line; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Humans; Immunoprecipitation; Inflammation; Lipopolysaccharides; Mice; Molecular Docking Simulation; Molecular Structure; Neurons; Peptide Fragments; Piperidones; Protein Aggregates; Protein Binding; Structure-Activity Relationship | 2016 |
Hepatoprotective effects of gemigliptin and empagliflozin in a murine model of diet-induced non-alcoholic fatty liver disease.
Topics: Amino Acids; Animals; Benzhydryl Compounds; Choline; Cytokines; Diet, High-Fat; Disease Models, Animal; Disease Progression; Glucosides; Inflammation; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Liver; Macrophage Activation; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phosphorylation; Piperidones; Protective Agents; Pyrimidines | 2022 |
Diarylidene-N-Methyl-4-Piperidones and Spirobibenzopyrans as Antioxidant and Anti-Inflammatory Agents.
Topics: Anti-Inflammatory Agents; Antioxidants; Curcumin; Humans; Inflammation; Nitric Oxide; Piperidones | 2023 |
Treatment of rheumatoid arthritis with curcumin analog 3,5-bis(arylidene)-4-piperidone.
Topics: Animals; Arthritis, Rheumatoid; Curcumin; Inflammation; Molecular Docking Simulation; NF-kappa B; Piperidones; Rats | 2023 |
11β-HSD1 Inhibition Rescues SAMP8 Cognitive Impairment Induced by Metabolic Stress.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Alzheimer Disease; Animals; Autophagy; Behavior, Animal; Biomarkers; Cognitive Dysfunction; Diet, High-Fat; eIF-2 Kinase; Female; Fibroblast Growth Factors; Glucocorticoids; Glucose Intolerance; Glycogen Synthase Kinase 3; Inflammation; Mice; Microglia; Piperidones; Pyridines; Signal Transduction; Social Behavior; Stress, Physiological | 2020 |
Discovery of novel NF-кB inhibitor based on scaffold hopping: 1,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidine.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line; Dose-Response Relationship, Drug; Drug Design; Humans; Inflammation; Lipopolysaccharides; Liver Neoplasms; MAP Kinase Signaling System; Mice; Molecular Docking Simulation; NF-kappa B; Phosphorylation; Piperidones; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2020 |
Biological and physical approaches on the role of piplartine (piperlongumine) in cancer.
Topics: Alkaloids; Annexin A1; Anti-Inflammatory Agents; Antineoplastic Agents; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemokine CCL2; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Neoplasm Invasiveness; Neoplasms; Piper; Piperidones; Tumor Microenvironment | 2020 |
Ameliorating Effect of Gemigliptin on Renal Injury in Murine Adriamycin-Induced Nephropathy.
Topics: Acute Kidney Injury; Animals; Apoptosis; Disease Models, Animal; Doxorubicin; Humans; Inflammation; Kidney Diseases; Male; Membrane Proteins; Mice; Oxidative Stress; Piperidones; Pyrimidines; Repressor Proteins; WT1 Proteins | 2017 |
11β-HSD1 Inhibition by RL-118 Promotes Autophagy and Correlates with Reduced Oxidative Stress and Inflammation, Enhancing Cognitive Performance in SAMP8 Mouse Model.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Alzheimer Disease; Animals; Anxiety; Autophagy; Beclin-1; Biomarkers; Cognition; Disease Models, Animal; Female; Inflammation; Memory; Mice; Mice, Neurologic Mutants; Microtubule-Associated Proteins; Models, Biological; Nerve Degeneration; Oxidative Stress; Piperidones; Pyridines; TOR Serine-Threonine Kinases | 2018 |
Gemigliptin Attenuates Renal Fibrosis Through Down-Regulation of the NLRP3 Inflammasome.
Topics: Administration, Oral; Animals; Cell Line; Diabetic Nephropathies; Dipeptidyl-Peptidase IV Inhibitors; Down-Regulation; Fibrosis; Humans; Inflammasomes; Inflammation; Kidney Tubules, Proximal; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Piperidones; Protective Agents; Pyrimidines; Signal Transduction; Transforming Growth Factor beta; Ureteral Obstruction | 2019 |
Discovery and evaluation of piperid-4-one-containing mono-carbonyl analogs of curcumin as anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Curcumin; Dose-Response Relationship, Drug; Drug Discovery; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Inflammation; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Piperidones; Sepsis; Signal Transduction; Structure-Activity Relationship; Survival Analysis | 2013 |
Dipeptidyl petidase-IV inhibitor (gemigliptin) inhibits tunicamycin-induced endoplasmic reticulum stress, apoptosis and inflammation in H9c2 cardiomyocytes.
Topics: Animals; Apoptosis; Cell Line; Cytokines; Dipeptidyl-Peptidase IV Inhibitors; eIF-2 Kinase; Endoplasmic Reticulum Stress; Endoribonucleases; Inflammation; Inflammation Mediators; Models, Biological; Multienzyme Complexes; Myocytes, Cardiac; Phosphorylation; Piperidones; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; Rats; RNA, Messenger; Signal Transduction; Transcription, Genetic; Tunicamycin | 2014 |
Differentiation of antiinflammatory and antitumorigenic properties of stabilized enantiomers of thalidomide analogs.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Female; Humans; Inflammation; Leukocytes, Mononuclear; Mice; Mice, SCID; Models, Chemical; Neoplasm Transplantation; Neoplasms; Piperidones; Quinazolinones; Stereoisomerism; Thalidomide; Tumor Necrosis Factor-alpha | 2015 |
Gemigliptin ameliorates Western-diet-induced metabolic syndrome in mice.
Topics: Adipocytes; Animals; Diet, Western; Fatty Liver; Fibrosis; Hypercholesterolemia; Hypertrophy; Inflammation; Insulin Resistance; Liver; Male; Metabolic Syndrome; Mice; Piperidones; Pyrimidines; Subcutaneous Fat; Uncoupling Protein 1; Weight Gain | 2017 |
Effects of BRL 55 834 on allergen-induced bronchoconstriction and airway inflammation in sensitized guinea pigs.
Topics: Animals; Asthma; Benzopyrans; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Cromakalim; Female; Guinea Pigs; Inflammation; Male; Ovalbumin; Piperidones; Potassium Channels; Verapamil | 1999 |