2-piperidone has been researched along with Disease Models, Animal in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (13.16) | 29.6817 |
| 2010's | 29 (76.32) | 24.3611 |
| 2020's | 4 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, W; Chen, Z; Cheng, S; Hu, S; Li, H; Ouyang, M; Peng, H; Xue, J; Yu, S; Zeng, W; Zhang, Y; Zhou, L | 1 |
| Choi, SE; Han, SJ; Heo, YJ; Jeon, JY; Kang, Y; Kim, DJ; Kim, HJ; Lee, KW; Lee, N | 1 |
| Chen, J; Chen, X; Dou, QP; He, Q; Jiang, L; Lan, X; Liu, J; Shi, X; Sun, Y; Wang, J | 1 |
| Antar, GM; Cogo, RM; Lago, JHG; Mazloum, SF; Mendonça, PS; Mengarda, AC; Moraes, J; Morais, CS; Morais, TR; Salvadori, MC; Teixeira, FS | 1 |
| Fu, D; Jiang, ZY; Lin, QL; Liu, JB; Ma, YS; Wang, XF; Wu, TM; Xia, Q; Yu, F; Zhang, YJ | 1 |
| He, S; Hou, J; Huang, Q; Tan, G; Xu, F; Yan, J; Yu, X; Zhang, X; Zhang, Z; Zheng, C | 1 |
| Ihm, CG; Jeong, KH; Kim, DR; Kim, JS; Kim, YG; Lee, SH; Lee, SY; Lee, TW; Moon, JY | 1 |
| Griñán-Ferré, C; Leiva, R; Pallàs, M; Puigoriol-Illamola, D; Vasilopoulou, F; Vázquez, S | 1 |
| Bird, TD; Guthrie, CR; Kraemer, BC; Leverenz, JB; Liachko, NF; McMillan, PJ | 1 |
| Araújo, J; Benzecry, R; Crespo-Lopez, ME; de Jesus Oliveira Batista, E; Herculano, AM; Lima, MG; Maximino, C; Puty, B; Renata de Matos Oliveira, K | 1 |
| Argüelles, CF; Godínez-Chaparro, B; Granados-Soto, V; López-Santillán, FJ; Villalón, CM | 1 |
| Awasthi, V; Roberts, PR; Sahoo, K; Yadav, VR | 1 |
| Moore, TM; Shoji, M; Snyder, JP; Wu, D; Yamaguchi, M; Zhang, S; Zhu, S | 1 |
| Awasthi, S; Awasthi, V; Vilekar, P; Yadav, VR | 1 |
| Kamiński, K; Obniska, J; Wiklik, B | 1 |
| Anguiano-Robledo, L; Lacivita, E; Leopoldo, M; López-Sánchez, P; Sánchez-Maldonado, C; Terrón, JA | 1 |
| Awasthi, V; Hussain, A; Kosanke, S; Xie, J; Yadav, VR | 1 |
| Cho, MH; Ho Kim, S; Jung, E; Kim, J; Kim, S | 1 |
| Armstrong, EA; Canon, J; Francis, DM; Harari, PM; Huang, S; Iyer, G; Li, C; Ma, F; Werner, LR | 1 |
| Choi, SH; Lee, IK; Leem, J; Oh, CJ; Park, KG; Park, S | 1 |
| Awasthi, V; Hedrick, A; Rao, G; Xie, J | 1 |
| Li, J; Liu, B; Liu, J; Liu, Y; Lu, Y; Wang, W | 1 |
| Gupta, N; Li, W; McIntyre, TM | 1 |
| Einama, T; Fukai, M; Funakoshi, T; Ichihara, S; Ichikawa, N; Kobayashi, N; Koshizuka, Y; Ogura, M; Ozaki, M; Sato, M; Shibasaki, S; Suzuki, T; Todo, S; Tsunetoshi, Y; Umezawa, K; Yamashita, K; Yoshida, T; Zaitsu, M | 1 |
| El-Salhy, M; Umezawa, K | 2 |
| Cheng, XW; Kim, DJ; Kim, SY; Kim, W; Kim, YG; Lee, A; Lee, KH; Lee, SH; Lim, SJ; Moon, JY; Seo, JW; Woo, JS | 1 |
| Chung, BH; Jin, J; Jin, L; Lim, SW; Yang, CW | 1 |
| Jacko, AM; Kass, DJ; Ma, H; Nan, L; Tan, J; Wang, D; Zhao, J; Zhao, Y | 1 |
| Cheng, D; Han, C; Lv, H; Xie, Z; Ye, F; Yu, S; Zhang, H; Zhang, Z | 1 |
| Centurión, D; González-Hernández, A; Lozano-Cuenca, J; Muñoz-Islas, E; Ramírez-Rosas, MB; Ramírez-San Juan, E; Sánchez-López, A; Villalón, CM | 1 |
| Agashe, H; Awasthi, V; Lagisetty, P; Sahoo, K | 1 |
| Brnjic, S; D'Arcy, P; De Cesare, M; Fryknäs, M; Hassan, M; Larsson, R; Linder, S; Lindsten, K; Olofsson, MH; Perego, P; Sadeghi, B | 1 |
| Grainger, DJ; Reckless, J | 1 |
| Matono, K; Ogata, Y; Shirouzu, K | 1 |
| Hoerauf, A; Holzgrabe, U; Kaiser, A; Njuguna, T; Saeftel, M; Sarite, RS; Ulmer, D | 1 |
| Andrade, Eda S; de Lima, TC; Duarte, FS; Nunes, RJ; Uieara, M; Vieira, RA | 1 |
| Alves, AP; Bezerra, DP; Castro, FO; Costa-Lotufo, LV; Elmiro, FJ; Lima, MA; Moraes, MO; Pessoa, C; Silveira, ER | 1 |
1 review(s) available for 2-piperidone and Disease Models, Animal
| Article | Year |
|---|---|
Broad-spectrum chemokine inhibitors (BSCIs) and their anti-inflammatory effects in vivo.
Topics: Animals; Anti-Inflammatory Agents; Cell Movement; Chemokine CCL2; Chemokines; Conserved Sequence; Disease Models, Animal; Humans; Inflammation; Peptides; Piperidones; Structure-Activity Relationship | 2003 |
37 other study(ies) available for 2-piperidone and Disease Models, Animal
| Article | Year |
|---|---|
The therapeutic effect and mechanism of Rapamycin combined with HO-3867 on monocrotaline-induced pulmonary hypertension in rats.
Topics: Animals; Disease Models, Animal; Hypertension, Pulmonary; Monocrotaline; Piperidones; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sirolimus | 2022 |
Hepatoprotective effects of gemigliptin and empagliflozin in a murine model of diet-induced non-alcoholic fatty liver disease.
Topics: Amino Acids; Animals; Benzhydryl Compounds; Choline; Cytokines; Diet, High-Fat; Disease Models, Animal; Disease Progression; Glucosides; Inflammation; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Liver; Macrophage Activation; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phosphorylation; Piperidones; Protective Agents; Pyrimidines | 2022 |
Proteasomal cysteine deubiquitinase inhibitor b-AP15 suppresses migration and induces apoptosis in diffuse large B cell lymphoma.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cell Line, Tumor; Cell Movement; Cell Survival; Deubiquitinating Enzymes; Disease Models, Animal; Humans; Lymphoma, Large B-Cell, Diffuse; Mice; Mice, Nude; Piperidones; Proteasome Inhibitors; Xenograft Model Antitumor Assays | 2019 |
Antiparasitic activity of piplartine (piperlongumine) in a mouse model of schistosomiasis.
Topics: Animals; Disease Models, Animal; Female; Mice; Piper; Piperidones; Schistosomiasis mansoni; Schistosomicides | 2020 |
Inhibition of USP14 and UCH37 deubiquitinating activity by b-AP15 as a potential therapy for tumors with p53 deficiency.
Topics: Animals; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Lymphoma; Piperidones; Tumor Suppressor Protein p53; Ubiquitin Thiolesterase | 2020 |
Antiviral activity of PHA767491 against human herpes simplex virus in vitro and in vivo.
Topics: Animals; Antiviral Agents; Cell Line; Disease Models, Animal; Drug Resistance, Viral; Gene Expression Regulation, Viral; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Mice; Microbial Sensitivity Tests; Piperidones; Pyrroles; Viral Proteins; Virus Replication | 2017 |
Ameliorating Effect of Gemigliptin on Renal Injury in Murine Adriamycin-Induced Nephropathy.
Topics: Acute Kidney Injury; Animals; Apoptosis; Disease Models, Animal; Doxorubicin; Humans; Inflammation; Kidney Diseases; Male; Membrane Proteins; Mice; Oxidative Stress; Piperidones; Pyrimidines; Repressor Proteins; WT1 Proteins | 2017 |
11β-HSD1 Inhibition by RL-118 Promotes Autophagy and Correlates with Reduced Oxidative Stress and Inflammation, Enhancing Cognitive Performance in SAMP8 Mouse Model.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Alzheimer Disease; Animals; Anxiety; Autophagy; Beclin-1; Biomarkers; Cognition; Disease Models, Animal; Female; Inflammation; Memory; Mice; Mice, Neurologic Mutants; Microtubule-Associated Proteins; Models, Biological; Nerve Degeneration; Oxidative Stress; Piperidones; Pyridines; TOR Serine-Threonine Kinases | 2018 |
CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.
Topics: Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Cycle Proteins; Cell Line, Transformed; Disease Models, Animal; DNA-Binding Proteins; Enzyme Inhibitors; Frontal Lobe; Gene Expression Regulation; Humans; Movement; Mutation; Neurodegenerative Diseases; Phosphorylation; Piperidones; Protein Serine-Threonine Kinases; Pyrroles; RNA, Small Interfering; Serine; TDP-43 Proteinopathies; Transfection | 2013 |
Role of serotonin in zebrafish (Danio rerio) anxiety: relationship with serotonin levels and effect of buspirone, WAY 100635, SB 224289, fluoxetine and para-chlorophenylalanine (pCPA) in two behavioral models.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Brain; Buspirone; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Fluid; Fenclonine; Fluoxetine; Hyperkinesis; Nerve Tissue Proteins; Neurons; Piperazines; Piperidones; Protein Isoforms; Pyridines; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Spiro Compounds; Zebrafish | 2013 |
Role of 5-HT₁B/₁D receptors in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats.
Topics: Acute Pain; Animals; Biphenyl Compounds; Chronic Pain; Dihydroergotamine; Disease Models, Animal; Drug Therapy, Combination; Female; Formaldehyde; Hyperalgesia; Methysergide; Nociceptive Pain; Piperazines; Piperidones; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Serotonin Antagonists; Spiro Compounds; Sumatriptan | 2013 |
Pharmacologic suppression of inflammation by a diphenyldifluoroketone, EF24, in a rat model of fixed-volume hemorrhage improves survival.
Topics: Animals; Anti-Inflammatory Agents; Benzylidene Compounds; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Heme Oxygenase (Decyclizing); Hypovolemia; Lung; Male; Nitric Oxide Synthase Type II; Piperidones; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Survival Analysis; Transcription Factor RelA | 2013 |
Curcumin analogue UBS109 prevents bone loss in breast cancer bone metastasis mouse model: involvement in osteoblastogenesis and osteoclastogenesis.
Topics: Animals; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Disease Models, Animal; Female; Humans; Mice; Mice, Nude; Neoplasm Metastasis; Osteoblasts; Osteoclasts; Piperidones; Pyridines; Xenograft Model Antitumor Assays | 2014 |
Hemorrhage-induced interleukin-1 receptor pathway in lung is suppressed by 3,5-bis(2-fluorobenzylidene)-4-piperidone in a rat model of hypovolemic shock.
Topics: Animals; Benzylidene Compounds; Disease Models, Animal; Lung; Male; NF-kappa B; Piperidones; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1; Shock, Hemorrhagic; Signal Transduction; Toll-Like Receptor 4 | 2014 |
Synthesis, anticonvulsant properties, and SAR analysis of differently substituted pyrrolidine-2,5-diones and piperidine-2,6-diones.
Topics: Animals; Anticonvulsants; Cell Death; Disease Models, Animal; Drug Design; Electric Stimulation; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Mice; Molecular Structure; Neuroprotective Agents; Pentylenetetrazole; Piperidones; Seizures; Structure-Activity Relationship; Succinimides; Time Factors | 2014 |
GR-127935-sensitive mechanism mediating hypotension in anesthetized rats: are 5-HT5B receptors involved?
Topics: Animals; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ergotamine; Hypotension; Oxadiazoles; Piperazines; Piperidones; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds | 2015 |
The salutary effects of diphenyldifluoroketone EF24 in liver of a rat hemorrhagic shock model.
Topics: Animals; Benzylidene Compounds; Disease Models, Animal; Immunoblotting; Immunohistochemistry; Liver; Piperidones; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic | 2015 |
Gemigliptin improves renal function and attenuates podocyte injury in mice with diabetic nephropathy.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Advanced Oxidation Protein Products; Albuminuria; Animals; Apoptosis; Blood Glucose; Cytoprotection; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Glomerular Filtration Rate; Guanine; Male; Mice, Inbred C57BL; Piperidones; Podocytes; Protein Serine-Threonine Kinases; Pyrimidines; Receptor for Advanced Glycation End Products | 2015 |
Small Molecule Inhibition of MDM2-p53 Interaction Augments Radiation Response in Human Tumors.
Topics: Acetates; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cellular Senescence; Disease Models, Animal; Humans; Mice; Neoplasms; Piperidones; Protein Binding; Proto-Oncogene Proteins c-mdm2; Radiation Tolerance; Radiation, Ionizing; Signal Transduction; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2015 |
Dipeptidyl peptidase-4 inhibition by gemigliptin prevents abnormal vascular remodeling via NF-E2-related factor 2 activation.
Topics: Animals; Carotid Artery Injuries; Cell Adhesion Molecules; Cell Movement; Cell Proliferation; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; G1 Phase Cell Cycle Checkpoints; HEK293 Cells; Humans; Hyperplasia; Male; Matrix Metalloproteinase 2; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; NF-E2-Related Factor 2; Piperidones; Pyrimidines; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Time Factors; Transfection; Vascular Remodeling | 2015 |
Hemorrhagic shock-induced cerebral bioenergetic imbalance is corrected by pharmacologic treatment with EF24 in a rat model.
Topics: Adenosine Triphosphate; Animals; Benzylidene Compounds; Brain; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Energy Metabolism; Male; Mitochondria; NAD; Nerve Growth Factor; Neuroprotective Agents; Phosphocreatine; Piperidones; Pyruvic Acid; Rats, Sprague-Dawley; Shock, Hemorrhagic | 2015 |
Leukemia inhibitory factor promotes tumor growth and metastasis in human osteosarcoma via activating STAT3.
Topics: Adolescent; Adult; Animals; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Child; Child, Preschool; Disease Models, Animal; Enzyme Activation; Female; Humans; Leukemia Inhibitory Factor; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Osteosarcoma; Phosphorylation; Piperidones; RNA Interference; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Transplantation, Heterologous; Young Adult | 2015 |
Deubiquitinases Modulate Platelet Proteome Ubiquitination, Aggregation, and Thrombosis.
Topics: Aminopyridines; Animals; Benzoates; Blood Platelets; Chlorides; Disease Models, Animal; Enzyme Inhibitors; Ferric Compounds; Furans; Humans; Mice, Inbred C57BL; Microfluidic Analytical Techniques; Microscopy, Interference; Piperidones; Platelet Aggregation; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Proteasome Endopeptidase Complex; Pyrazoles; Receptors, Collagen; Receptors, Thrombin; Signal Transduction; Thiocyanates; Thrombosis; Ubiquitin Thiolesterase; Ubiquitin-Specific Proteases; Ubiquitination | 2015 |
Novel anti-inflammatory agent 3-[(dodecylthiocarbonyl)-methyl]-glutarimide ameliorates murine models of inflammatory bowel disease.
Topics: Animals; Anti-Inflammatory Agents; CD4-Positive T-Lymphocytes; Cell Line; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Peroxidase; Piperidones; RNA, Messenger; Trinitrobenzenesulfonic Acid | 2016 |
Treatment with novel AP-1 and NF-κB inhibitors restores the colonic endocrine cells to normal levels in rats with DSS-induced colitis.
Topics: Animals; Anti-Inflammatory Agents; Benzamides; Carboxymethylcellulose Sodium; Colitis; Colon; Cyclohexanones; Dextran Sulfate; Disease Models, Animal; Endocrine Cells; Male; NF-kappa B; Piperidones; Rats; Rats, Wistar; Transcription Factor AP-1 | 2016 |
The Dose-Dependent Organ-Specific Effects of a Dipeptidyl Peptidase-4 Inhibitor on Cardiovascular Complications in a Model of Type 2 Diabetes.
Topics: Albuminuria; Animals; Apoptosis; Cardiomegaly; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Forkhead Box Protein O3; Forkhead Transcription Factors; Glucagon-Like Peptide 1; Glycated Hemoglobin; Immunohistochemistry; Kidney; Male; Mice; NADPH Oxidases; Piperidones; Podocytes; Proto-Oncogene Proteins c-akt; Pyrimidines; Ventricular Dysfunction | 2016 |
Effects of addition of a dipeptidyl peptidase IV inhibitor to metformin on sirolimus-induced diabetes mellitus.
Topics: Animals; Apoptosis; Cell Survival; Diabetes Mellitus, Experimental; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Drug Therapy, Combination; Exenatide; Hyperglycemia; Islets of Langerhans; Male; Metformin; Mitochondria; Oxidative Stress; Peptides; Piperidones; Pyrimidines; Rats, Sprague-Dawley; Reactive Oxygen Species; Sirolimus; Venoms | 2016 |
Effects of AP‑1 and NF‑κB inhibitors on colonic endocrine cells in rats with TNBS‑induced colitis.
Topics: Animals; Benzamides; Biomarkers; Body Weight; Chromogranin A; Colitis; Cyclohexanones; Disease Models, Animal; Endocrine Cells; Gene Expression; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; NF-kappa B; Piperidones; Rats; Serotonin; Transcription Factor AP-1; Trinitrobenzenesulfonic Acid | 2016 |
Ubiquitin carboxyl-terminal hydrolase-L5 promotes TGFβ-1 signaling by de-ubiquitinating and stabilizing Smad2/Smad3 in pulmonary fibrosis.
Topics: Animals; Bleomycin; Cell Line; Cells, Cultured; Disease Models, Animal; Humans; Idiopathic Pulmonary Fibrosis; Mice; Mice, Inbred C57BL; Piperidones; Protein Stability; Proteolysis; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1; Ubiquitin Thiolesterase; Ubiquitination | 2016 |
Synthesis and Evaluation of Anti-inflammatory N-Substituted 3,5-Bis(2-(trifluoromethyl)benzylidene)piperidin-4-ones.
Topics: Animals; Anti-Inflammatory Agents; Bone Marrow Cells; Carrageenan; Celecoxib; Cell Survival; Dinoprostone; Disease Models, Animal; Edema; Enzyme-Linked Immunosorbent Assay; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Piperidones; Rats; RAW 264.7 Cells; Structure-Activity Relationship; Tissue Distribution; Tumor Necrosis Factor-alpha | 2017 |
Activation of 5-HT1B receptors inhibits the vasodepressor sensory CGRPergic outflow in pithed rats.
Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Hexamethonium; Infusions, Intravenous; Male; Methoxamine; Piperidones; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Sodium Chloride; Spinal Cord; Spiro Compounds; Time Factors; Vasoconstrictor Agents | 2010 |
Cyclodextrin-mediated entrapment of curcuminoid 4-[3,5-bis(2-chlorobenzylidene-4-oxo-piperidine-1-yl)-4-oxo-2-butenoic acid] or CLEFMA in liposomes for treatment of xenograft lung tumor in rats.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Cyclodextrins; Disease Models, Animal; Drug Delivery Systems; Liposomes; Lung Neoplasms; Piperidones; Rats | 2011 |
Inhibition of proteasome deubiquitinating activity as a new cancer therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Boronic Acids; Bortezomib; Breast Neoplasms; Carboxypeptidases; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; Humans; Mice; Mice, Inbred BALB C; Mice, SCID; Microarray Analysis; Multiple Myeloma; Piperidones; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Tumor Suppressor Protein p53; Ubiquitin; Ubiquitin Thiolesterase; Ubiquitination | 2011 |
[Anti-proliferative effects of biochemical defense modifier antineoplaston in colorectal carcinoma].
Topics: Animals; Apoptosis; Benzeneacetamides; Cell Cycle; Cell Cycle Proteins; Colorectal Neoplasms; Depression, Chemical; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Glutamine; Humans; Lung Neoplasms; Mice; Mice, Nude; Phenylacetates; Piperidones; Tumor Cells, Cultured | 2003 |
Piperidones with activity against Plasmodium falciparum.
Topics: Animals; Antimalarials; Ciclopirox; Disease Models, Animal; Malaria; Mice; Mice, Inbred BALB C; Mimosine; Molecular Structure; Parasitemia; Piperidones; Plasmodium berghei; Plasmodium falciparum; Pyridones | 2006 |
Synthesis and antidepressant-like action of stereoisomers of imidobenzenesulfonylaziridines in mice evaluated in the forced swimming test.
Topics: Alkaloids; Animals; Antidepressive Agents; Aziridines; Behavior, Animal; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Imipramine; Immersion; Male; Mice; Molecular Structure; Motor Activity; Phyllanthus; Piperidones; Stereoisomerism; Sulfones; Swimming | 2006 |
In vivo growth-inhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper.
Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Benzodioxoles; Cell Proliferation; Disease Models, Animal; Female; Kidney; Liver; Mice; Neoplasm Transplantation; Piper; Piperidines; Piperidones; Plant Extracts; Plant Roots; Polyunsaturated Alkamides; Sarcoma 180; Spleen | 2006 |