2-piperidone has been researched along with Cancer of Pancreas in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (90.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Axelrod, K; Bognár, B; Hinds, JW; Kálai, T; Kmiec, MM; Kuppusamy, ML; Kuppusamy, P; Mast, JM; Tse, D | 1 |
| Kálai, T; Kmiec, MM; Kuppusamy, P; Lakshmi Kuppusamy, M; Mast, JM; Shee, K; Tse, D | 1 |
| Adsay, VN; Diaz, R; El-Rayes, BF; Farris, AB; Mamoru, S; Nagaraju, GP; Snyder, JP; Wen, J; Zhu, S | 1 |
| Anderson, KI; Lo Re, D; Murphy, PV; Nobis, M; Zhou, Y | 1 |
| Ashritha, N; El-Rayes, BF; Kandimalla, R; Ko, JE; Nagaraju, GP; Shoji, M; Snyder, JP; Zhu, S | 1 |
| Jones, LF; Krol, M; Leahy, L; Lo Re, D; Mucha, J; Murphy, PV; Santocanale, C; Zhou, Y | 1 |
| Huggett, MT; Keane, MG; Loddo, M; Pereira, SP; Proctor, I; Stoeber, K; Tudzarova, S; Williams, GH | 1 |
| Bendas, G; Bisht, S; Brossart, P; Feldmann, G; Holdenrieder, S; Nolting, J; Rupp, A; Schlesinger, M; Schubert, R; Wenzel, J | 1 |
| Dai, X; Hu, W; Hu, Y; Liang, G; Liu, Z; Lu, K; Shi, D; Zhang, X; Zhang, Y; Zhao, C; Zheng, H | 1 |
| Anant, S; Awasthi, V; Dhar, A; Jensen, RA; Nicholes, ND; Subramaniam, D; Umar, S; Welch, DR | 1 |
10 other study(ies) available for 2-piperidone and Cancer of Pancreas
| Article | Year |
|---|---|
Selective Induction of Cellular Toxicity and Anti-tumor Efficacy by N-Methylpiperazinyl Diarylidenylpiperidone and its Pro-nitroxide Conjugate through ROS-mediated Mitochondrial Dysfunction and G2/M Cell-cycle Arrest in Human Pancreatic Cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Electron Spin Resonance Spectroscopy; G2 Phase; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Mitochondria; Neoplasm Transplantation; Oximetry; Pancreatic Neoplasms; Piperazines; Piperidones; Reactive Oxygen Species | 2020 |
Diarylidenylpiperidones, H-4073 and HO-3867, Induce G2/M Cell-Cycle Arrest, Apoptosis and Inhibit STAT3 Phosphorylation in Human Pancreatic Cancer Cells.
Topics: Apoptosis; Biomarkers, Tumor; Cell Line, Tumor; Cyclin D1; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Mitochondria; Pancreatic Neoplasms; Phosphorylation; Piperidones; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; STAT3 Transcription Factor | 2019 |
Novel synthetic curcumin analogues EF31 and UBS109 are potent DNA hypomethylating agents in pancreatic cancer.
Topics: Animals; Blotting, Western; Cadherins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcumin; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Immunohistochemistry; Mice; Mice, Nude; Osteonectin; Pancreatic Neoplasms; Piperidones; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Xenograft Model Antitumor Assays | 2013 |
Synthesis of migrastatin and its macroketone analogue and in vivo FRAP analysis of the macroketone on E-cadherin dynamics.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cadherins; Cell Adhesion; Cell Movement; Fluorescence Recovery After Photobleaching; Humans; Macrolides; Mice, Nude; Pancreatic Neoplasms; Piperidones; Tumor Cells, Cultured | 2014 |
Antiangiogenic effects of a novel synthetic curcumin analogue in pancreatic cancer.
Topics: Angiogenesis Inhibitors; Angiopoietins; Animals; Blotting, Western; Cell Line; Cell Line, Tumor; Chick Embryo; Chorioallantoic Membrane; Culture Media, Conditioned; Curcumin; Female; Gene Expression; HSP90 Heat-Shock Proteins; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice, Nude; Neovascularization, Pathologic; Neovascularization, Physiologic; Pancreatic Neoplasms; Piperidones; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2015 |
Synthesis of Migrastatin Analogues as Inhibitors of Tumour Cell Migration: Exploring Structural Change in and on the Macrocyclic Ring.
Topics: Alkenes; Cell Line, Tumor; Cell Movement; Female; Glucuronides; Humans; Macrocyclic Compounds; Macrolides; Pancreatic Neoplasms; Piperidones; Structure-Activity Relationship | 2015 |
Cdc7 is a potent anti-cancer target in pancreatic cancer due to abrogation of the DNA origin activation checkpoint.
Topics: Adenocarcinoma; Cell Cycle Proteins; Cell Line, Tumor; Cohort Studies; DNA Replication; G1 Phase Cell Cycle Checkpoints; Humans; Molecular Targeted Therapy; Pancreatic Neoplasms; Piperidones; Protein Serine-Threonine Kinases; Pyrroles; Transfection | 2016 |
A liposomal formulation of the synthetic curcumin analog EF24 (Lipo-EF24) inhibits pancreatic cancer progression: towards future combination therapies.
Topics: Animals; Antineoplastic Agents; Benzylidene Compounds; Cell Line, Tumor; Cell Survival; Deoxycytidine; Disease Progression; Drug Compounding; Drug Therapy, Combination; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; I-kappa B Kinase; Injections, Subcutaneous; Liposomes; Mice; NF-kappa B; Pancreatic Neoplasms; Phosphorylation; Piperidones; Signal Transduction; Xenograft Model Antitumor Assays | 2016 |
A novel STAT3 inhibitor HO-3867 induces cell apoptosis by reactive oxygen species-dependent endoplasmic reticulum stress in human pancreatic cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Endoplasmic Reticulum Stress; Humans; MAP Kinase Signaling System; Pancreatic Neoplasms; Piperidones; Reactive Oxygen Species; STAT3 Transcription Factor | 2017 |
3,5-bis(2,4-difluorobenzylidene)-4-piperidone, a novel compound that affects pancreatic cancer growth and angiogenesis.
Topics: Amyloid Precursor Protein Secretases; Animals; Antineoplastic Agents; Apoptosis; Benzylidene Compounds; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Pancreatic Neoplasms; Piperidones; Receptors, Notch; Xenograft Model Antitumor Assays | 2011 |