2-piperidone has been researched along with Cancer of Ovary in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 14 (87.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bixel, K; Cohn, DE; Deepa Priya Dorayappan, K; Fowler, J; Konishi, I; Kumar Bid, H; Matsumura, N; Rajendran, S; Riley, M; Saini, U; Selvendiran, K; Wanner, R | 1 |
| Ben, W; Dong, L; Guan, Y; Huang, Y; Lu, M; Ning, N; Wang, Y; Yang, Y; Yuan, J; Zhang, D | 1 |
| Bid, HK; Bravo, V; Cohn, DE; Elnaggar, AC; Hideg, K; Houghton, P; Kuppusamy, P; Lata, P; Leone, G; McCann, GA; Naidu, SK; Rath, KS; Rivera, BK; Selvendiran, K; Tierney, BJ | 1 |
| Anchoori, R; Bazzaro, M; Coughlin, K; Iizuka, Y; Lee, MK; MacNeill, L; Meints, J; Orlowski, RZ; Roden, RB; Vogel, RI | 1 |
| Bid, HK; Bixel, K; Bolyard, C; Cohn, DE; ElNaggar, AC; Goodfellow, PJ; Hays, J; Kaur, B; Kuppusamy, P; Naidu, S; Saini, U; Selvendiran, K; Suarez, AA; Wallbillich, JJ | 1 |
| Cohn, DE; ElNaggar, AC; Fowler, J; Kuppusamy, P; Nagane, M; Naidu, S; Saini, U; Selvendiran, K; Sudhakar, M; Wanner, R | 1 |
| Chen, GG; Gong, X; He, T; Liang, N; Lv, Y; Wu, K | 1 |
| Khrustalev, VN; Leonova, ES; Makarov, MV; Odinets, IL; Rybalkina, EY; Timofeeva, TV; Tongwa, P | 1 |
| Ahmed, S; Bratasz, A; Hideg, K; Kálai, T; Kuppusamy, ML; Kuppusamy, P; Ravi, Y; Rivera, BK; Selvendiran, K; Tong, L; Trigg, NJ | 1 |
| Horowitz, IR; Huang, RP; Liotta, DC; Mancini, A; Sidell, N; Tan, X; Taylor, RN; Wieser, F | 1 |
| Ahmed, S; Bratasz, A; Dayton, A; Hideg, K; Kálai, T; Kuppusamy, ML; Kuppusamy, P; Ravi, Y; Rivera, BK; Selvendiran, K | 1 |
| Dayton, A; Hideg, K; Kálai, T; Kuppusamy, ML; Kuppusamy, P; Meduru, S; Rivera, BK; Selvendiran, K | 1 |
| Ahmed, S; Dayton, A; Hideg, K; Kálai, T; Kuppusamy, ML; Kuppusamy, P; Rivera, BK; Selvendiran, K | 1 |
| Amerik, AY; Issaenko, OA | 1 |
| Cohn, DE; Eisenhauer, E; Hideg, K; Kuppusamy, P; McCann, GA; Selvendiran, K; Sudhakar, M; Tierney, BJ | 1 |
| Bratasz, A; Hideg, K; Kuppusamy, P; Kutala, VK; Selvendiran, K; Tong, L; Trigg, NJ; Vishwanath, S | 1 |
16 other study(ies) available for 2-piperidone and Cancer of Ovary
| Article | Year |
|---|---|
Targeting STAT3 by HO3867 induces apoptosis in ovarian clear cell carcinoma.
Topics: Adenocarcinoma, Clear Cell; Animals; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Ovarian Neoplasms; Piperidones; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2017 |
Therapeutic role of EF24 targeting glucose transporter 1-mediated metabolism and metastasis in ovarian cancer cells.
Topics: Animals; Benzylidene Compounds; Biological Transport; Cell Line, Tumor; Cell Movement; Cell Proliferation; Energy Metabolism; Female; Glucose; Glucose Transporter Type 1; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Transplantation; Ovarian Neoplasms; Peritoneal Neoplasms; Piperidones | 2013 |
HO-3867, a safe STAT3 inhibitor, is selectively cytotoxic to ovarian cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Growth Processes; Cell Line, Tumor; CHO Cells; Cricetulus; Cytotoxicity, Immunologic; Female; Humans; Ovarian Neoplasms; Piperidones; Signal Transduction; STAT3 Transcription Factor; Transcriptional Activation; Transfection; Xenograft Model Antitumor Assays | 2014 |
Small-molecule RA-9 inhibits proteasome-associated DUBs and ovarian cancer in vitro and in vivo via exacerbating unfolded protein responses.
Topics: Animals; Apoptosis; Benzylidene Compounds; Blotting, Western; Cell Cycle; Cell Proliferation; Female; Flow Cytometry; Humans; Immunoenzyme Techniques; In Vitro Techniques; Mice; Mice, Nude; Ovarian Neoplasms; Piperidones; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Small Molecule Libraries; Tumor Cells, Cultured; Ubiquitin; Ubiquitin-Specific Proteases; Unfolded Protein Response; Xenograft Model Antitumor Assays | 2014 |
Elevated STAT3 expression in ovarian cancer ascites promotes invasion and metastasis: a potential therapeutic target.
Topics: Animals; Ascites; Cell Movement; Female; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Ovarian Neoplasms; Piperidones; Signal Transduction; STAT3 Transcription Factor; Up-Regulation; Xenograft Model Antitumor Assays | 2017 |
Anticancer potential of diarylidenyl piperidone derivatives, HO-4200 and H-4318, in cisplatin resistant primary ovarian cancer.
Topics: Antineoplastic Agents; Cisplatin; Drug Resistance, Neoplasm; Female; Humans; Ovarian Neoplasms; Piperidones; Signal Transduction; STAT3 Transcription Factor | 2016 |
[Effect of 5F from Pteris semipinnata on expression of Nr1d1 in HO-8910PM cell line].
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Gene Expression; Humans; Neoplasm Invasiveness; Ovarian Neoplasms; Piperidones; Pteris; RNA, Messenger | 2009 |
Synthesis, characterization and structure-activity relationship of novel N-phosphorylated E,E-3,5-bis(thienylidene)piperid-4-ones.
Topics: Antineoplastic Agents; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Female; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Nitrogen; Ovarian Neoplasms; Phosphorylation; Piperidones; Structure-Activity Relationship; Thiophenes | 2010 |
Anticancer efficacy of a difluorodiarylidenyl piperidone (HO-3867) in human ovarian cancer cells and tumor xenografts.
Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Ovarian Neoplasms; Piperidones; Treatment Outcome; Xenograft Model Antitumor Assays | 2010 |
Multiple anticancer activities of EF24, a novel curcumin analog, on human ovarian carcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Benzylidene Compounds; Cell Line, Tumor; Cell Proliferation; Female; Humans; Ovarian Neoplasms; Piperidones; Reverse Transcriptase Polymerase Chain Reaction; RNA; Vascular Endothelial Growth Factor A | 2010 |
HO-3867, a synthetic compound, inhibits the migration and invasion of ovarian carcinoma cells through downregulation of fatty acid synthase and focal adhesion kinase.
Topics: Animals; Cell Line, Tumor; Cell Movement; Down-Regulation; Fatty Acid Synthases; Female; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Invasiveness; Ovarian Neoplasms; Piperidones; Proteasome Endopeptidase Complex; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2010 |
Cellular uptake, retention and bioabsorption of HO-3867, a fluorinated curcumin analog with potential antitumor properties.
Topics: Animals; Antineoplastic Agents; Curcumin; Electron Spin Resonance Spectroscopy; Female; Halogenation; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Piperidones; Rats; Rats, Wistar; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2010 |
HO-3867, a curcumin analog, sensitizes cisplatin-resistant ovarian carcinoma, leading to therapeutic synergy through STAT3 inhibition.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cisplatin; Curcumin; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Piperidones; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2011 |
Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymes.
Topics: Antineoplastic Agents; Apoptosis; Benzylidene Compounds; Boronic Acids; Bortezomib; Breast Neoplasms; Catalytic Domain; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Chalcone; Cyclin D1; Cysteine; Dose-Response Relationship, Drug; Endopeptidases; Female; HeLa Cells; Humans; Ovarian Neoplasms; Phenotype; Piperidones; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Tumor Suppressor Protein p53; Ubiquitin Thiolesterase; Ubiquitins | 2012 |
HO-3867, a STAT3 inhibitor induces apoptosis by inactivation of STAT3 activity in BRCA1-mutated ovarian cancer cells.
Topics: Antineoplastic Agents; Apoptosis; BRCA1 Protein; BRCA2 Protein; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclic S-Oxides; Cyclin D1; Drug Screening Assays, Antitumor; Female; Humans; Ovarian Neoplasms; Phosphorylation; Piperidones; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; STAT3 Transcription Factor | 2012 |
EF24 induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by increasing PTEN expression.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzylidene Compounds; Caspase Inhibitors; Caspases; Cell Division; Cell Survival; Cisplatin; Cysteine Proteinase Inhibitors; Drug Resistance, Neoplasm; Fas Ligand Protein; Female; G2 Phase; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Ovarian Neoplasms; Phosphorylation; Piperidones; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; PTEN Phosphohydrolase; RNA, Small Interfering; Time Factors; Tumor Suppressor Protein p53; Ubiquitin; Up-Regulation; Xenograft Model Antitumor Assays | 2007 |