2-piperidone has been researched along with Breast Cancer in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 14 (60.87) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Branco, PC; Costa-Lotufo, LV; Dartora, VFC; Lopes, LB; Passos, JS; Salata, GC; Silveira, E; Steiner, AA | 1 |
| Gaboriau, D; Quachthithu, H; Rainey, MD; Santocanale, C | 1 |
| Abdelbary, AA; Aboumanei, MH; El-Kolaly, MT; Ibrahim, IT; Tadros, MI | 2 |
| Kabiraj, P; Pal, R; Roy, D | 1 |
| Moore, TM; Shoji, M; Snyder, JP; Wu, D; Yamaguchi, M; Zhang, S; Zhu, S | 1 |
| Shoji, M; Snyder, JP; Weitzmann, MN; Yamaguchi, M; Zhu, S | 1 |
| Meegan, MJ; Nathwani, S; O'Boyle, NM; Twamley, B; Zisterer, DM | 1 |
| Danishefsky, SJ; Krauss, IJ; Mandal, M; Massagué, J; Moore, MA; Nagorny, P; Oskarsson, T; Ouerfelli, O; Perez, L; Xiao, D; Yang, G | 1 |
| Chen, L; Huang, XY; Jakoncic, J; Yang, S; Zhang, JJ | 1 |
| Aboussekhra, A; Al-Haza'a, A; Al-Hujaily, EM; Al-Hussein, K; Al-Jammaz, I; Al-Otaibi, B; Al-Sharif, I; Manogaran, PS; Mohamed, AG; Youssef, KM | 1 |
| Dayton, A; Hideg, K; Kálai, T; Khan, M; Kuppusamy, ML; Kuppusamy, P; Meduru, S; Naidu, S; Selvendiran, K | 1 |
| Brnjic, S; D'Arcy, P; De Cesare, M; Fryknäs, M; Hassan, M; Larsson, R; Linder, S; Lindsten, K; Olofsson, MH; Perego, P; Sadeghi, B | 1 |
| Amerik, AY; Issaenko, OA | 1 |
| Larsen, L; Rosengren, RJ; Taurin, S; Yadav, B | 1 |
| Chen, L; Danishefsky, SJ; Gaul, C; Huang, XY; Ma, X; Njardarson, JT; Shan, D | 1 |
| Fujii, T; Kawamura, D; Kuwano, M; Miwa, K; Nakamura, AM; Shirouzu, K; Tayama, K; Toh, U; Tsuda, H; Yamaguchi, M; Yamana, H; Yokoyama, G | 1 |
| Baker, HL; Bewley, CA; Chen, L; Huang, XY; Metaferia, BB | 1 |
| Chandra, D; Choy, G; Tang, DG | 1 |
| Chu, CK; Copland, JA; Hendry, LB; Mahesh, VB | 1 |
| Abou-Zeid, L; Badria, F; Khafagy, W; Mabed, M | 1 |
| Abou-Zeid, L; Al-Nashar, E; Badria, F; El-Awadi, M; Hawas, S; Mabed, M | 1 |
| Hara, H; Hashimoto, K; Kakegawa, T; Koga, T; Shintomi, Y; Tanaka, M; Tsuda, H | 1 |
23 other study(ies) available for 2-piperidone and Breast Cancer
| Article | Year |
|---|---|
Hyaluronic acid nanoemulsions improve piplartine cytotoxicity in 2D and 3D breast cancer models and reduce tumor development after intraductal administration.
Topics: Breast Neoplasms; Chitosan; Female; Humans; Hyaluronic Acid; Nanoparticles; Piperidones | 2022 |
DNA Replication Dynamics and Cellular Responses to ATP Competitive CDC7 Kinase Inhibitors.
Topics: Adenosine Triphosphate; Binding, Competitive; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Replication; Female; Humans; Phosphorylation; Piperidones; Protein Serine-Threonine Kinases; Pyrimidinones; Pyrroles | 2017 |
Design and development of microemulsion systems of a new antineoplaston A10 analog for enhanced intravenous antitumor activity: In vitro characterization, molecular docking,
Topics: Animals; Antineoplastic Agents; Benzeneacetamides; Breast Neoplasms; Carcinoma, Ehrlich Tumor; Drug Compounding; Emulsions; Ethanol; Female; Histone Deacetylases; Humans; Injections, Intravenous; Iodine Radioisotopes; Male; MCF-7 Cells; Microscopy, Electron, Transmission; Molecular Docking Simulation; Piperidones; Polysorbates; Rabbits; Repressor Proteins; Technology, Pharmaceutical; Tissue Distribution | 2018 |
Improved Targeting and Tumor Retention of a Newly Synthesized Antineoplaston A10 Derivative by Intratumoral Administration: Molecular Docking, Technetium 99m Radiolabeling, and In Vivo Biodistribution Studies.
Topics: Animals; Antineoplastic Agents; Benzeneacetamides; Breast Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Drug Screening Assays, Antitumor; Emulsions; Female; Humans; Injections, Intralesional; Injections, Intravenous; Mice; Molecular Docking Simulation; Particle Size; Piperidones; Technetium; Tissue Distribution; Xenograft Model Antitumor Assays | 2018 |
EF24 prevents rotenone-induced estrogenic status alteration in breast cancer.
Topics: Benzylidene Compounds; Breast Neoplasms; Down-Regulation; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; HEK293 Cells; HeLa Cells; Humans; MCF-7 Cells; Microscopy, Confocal; Oxidative Stress; Piperidones; Protein Disulfide-Isomerases; Reactive Oxygen Species; Rotenone; Up-Regulation | 2014 |
Curcumin analogue UBS109 prevents bone loss in breast cancer bone metastasis mouse model: involvement in osteoblastogenesis and osteoclastogenesis.
Topics: Animals; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Disease Models, Animal; Female; Humans; Mice; Mice, Nude; Neoplasm Metastasis; Osteoblasts; Osteoclasts; Piperidones; Pyridines; Xenograft Model Antitumor Assays | 2014 |
Curcumin analog UBS109 prevents bone marrow osteoblastogenesis and osteoclastogenesis disordered by coculture with breast cancer MDA-MB-231 bone metastatic cells in vitro.
Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Bone Neoplasms; Breast Neoplasms; Cell Differentiation; Cell Line, Tumor; Coculture Techniques; Female; Humans; Mice; Osteoblasts; Osteoclasts; Piperidones; Pyridines | 2015 |
Piperlongumine (piplartine) and analogues: Antiproliferative microtubule-destabilising agents.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Dioxolanes; Female; Humans; MCF-7 Cells; Microtubules; Models, Molecular; Piperidones; Reactive Oxygen Species; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2017 |
Diverted total synthesis leads to the generation of promising cell-migration inhibitors for treatment of tumor metastasis: in vivo and mechanistic studies on the migrastatin core ether analog.
Topics: Animals; Antineoplastic Agents; Biological Products; Breast Neoplasms; Cell Movement; Drug Screening Assays, Antitumor; Ethers; Female; Humans; Macrolides; Mice; Molecular Conformation; Neoplasm Metastasis; Piperidones; Stereoisomerism | 2010 |
Migrastatin analogues target fascin to block tumour metastasis.
Topics: Actins; Animals; Antineoplastic Agents; Binding Sites; Breast Neoplasms; Carrier Proteins; Cell Line, Tumor; Cell Movement; Crystallography, X-Ray; Drug Resistance, Neoplasm; Female; Humans; Lung Neoplasms; Macrolides; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Microfilament Proteins; Models, Molecular; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Piperidones; Protein Conformation | 2010 |
PAC, a novel curcumin analogue, has anti-breast cancer properties with higher efficiency on ER-negative cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Benzylidene Compounds; Brain Chemistry; Breast Neoplasms; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Female; G2 Phase; Genes, Neoplasm; Humans; Interferon-gamma; Interleukin-10; Interleukin-4; Mice; Mice, Nude; Mitochondria; Myocardium; Piperidones; Receptors, Estrogen; Tissue Distribution; Xenograft Model Antitumor Assays | 2011 |
Amelioration of doxorubicin-induced cardiotoxicity by an anticancer-antioxidant dual-function compound, HO-3867.
Topics: Animals; Antineoplastic Agents; Antioxidants; Aorta; Breast Neoplasms; Cardiotonic Agents; Caspases; Cell Line, Tumor; Cyclins; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Echocardiography; fas Receptor; Female; Heart; Heart Diseases; Humans; Male; Mice; Mice, Inbred BALB C; Piperidones; Proto-Oncogene Proteins c-akt | 2011 |
Inhibition of proteasome deubiquitinating activity as a new cancer therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Boronic Acids; Bortezomib; Breast Neoplasms; Carboxypeptidases; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; Humans; Mice; Mice, Inbred BALB C; Mice, SCID; Microarray Analysis; Multiple Myeloma; Piperidones; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Tumor Suppressor Protein p53; Ubiquitin; Ubiquitin Thiolesterase; Ubiquitination | 2011 |
Chalcone-based small-molecule inhibitors attenuate malignant phenotype via targeting deubiquitinating enzymes.
Topics: Antineoplastic Agents; Apoptosis; Benzylidene Compounds; Boronic Acids; Bortezomib; Breast Neoplasms; Catalytic Domain; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Chalcone; Cyclin D1; Cysteine; Dose-Response Relationship, Drug; Endopeptidases; Female; HeLa Cells; Humans; Ovarian Neoplasms; Phenotype; Piperidones; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Tumor Suppressor Protein p53; Ubiquitin Thiolesterase; Ubiquitins | 2012 |
RL66 a second-generation curcumin analog has potent in vivo and in vitro anticancer activity in ER‑negative breast cancer models.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Nude; Neovascularization, Pathologic; Piperidones; Pyridines; Receptor, ErbB-2; Receptors, Estrogen; Signal Transduction; Xenograft Model Antitumor Assays | 2012 |
Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Humans; Lactones; Lung Neoplasms; Macrolides; Mice; Neoplasm Metastasis; Piperidones; rac GTP-Binding Proteins | 2005 |
Antineoplaston induces G(1) arrest by PKCalpha and MAPK pathway in SKBR-3 breast cancer cells.
Topics: Benzeneacetamides; Blotting, Western; Breast Neoplasms; Carbazoles; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; G1 Phase; Humans; Indoles; Isoenzymes; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphorylation; Piperidones; Protein Kinase C; Protein Kinase C-alpha; Retinoblastoma Protein; Time Factors; Tumor Suppressor Proteins | 2005 |
Synthetic macrolides that inhibit breast cancer cell migration in vitro.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Movement; Female; Humans; Lactones; Macrolides; Models, Chemical; Piperidones; Quinic Acid; Tumor Cells, Cultured | 2007 |
Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3.
Topics: Apoptosis; Breast Neoplasms; Caspase 3; Cell Line, Transformed; Cell Line, Tumor; Cells, Cultured; Chaperonin 60; Cytosol; Down-Regulation; Enzyme Activation; Female; Fibroblasts; Fluorescent Dyes; HCT116 Cells; Humans; Hydroxamic Acids; Indoles; Male; Mitochondria; Piperidones; Prostatic Neoplasms; Recombinant Proteins; RNA, Messenger; RNA, Small Interfering; Subcellular Fractions; Time Factors; Transfection | 2007 |
Antiestrogenic piperidinediones designed prospectively using computer graphics and energy calculations of DNA-ligand complexes.
Topics: Benzeneacetamides; Breast Neoplasms; Computer-Aided Design; DNA, Neoplasm; Drug Design; Estrogen Antagonists; Humans; Ligands; Piperidones; Thermodynamics; Tumor Cells, Cultured | 1994 |
Potential utility of antineoplaston A-10 levels in breast cancer.
Topics: Adult; Aged; Benzeneacetamides; Breast Neoplasms; Case-Control Studies; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Female; Humans; Middle Aged; Peptides; Piperidones; Risk | 2000 |
Immune modulatory potentials of antineoplaston A-10 in breast cancer patients.
Topics: Adjuvants, Immunologic; Adult; Aged; Apoptosis; Benzeneacetamides; Breast Neoplasms; Cells, Cultured; DNA Fragmentation; Female; Humans; Middle Aged; Neutrophils; Piperidones | 2000 |
The anticancer effect of antineoplaston A-10 on human breast cancer serially transplanted to athymic mice.
Topics: Animals; Antineoplastic Agents; Benzeneacetamides; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Piperidines; Piperidones; Transplantation, Heterologous | 1990 |