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2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one and Anxiety

2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one has been researched along with Anxiety in 18 studies

*Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS. [MeSH]

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199015 (83.33)18.7374
1990's2 (11.11)18.2507
2000's1 (5.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Babich, M; Branda, EM; Elfline, GS; Quock, RM1
File, SE; Lister, RG2
Williams, M1
Crawley, JN; Paul, SM; Skolnick, P1
Paul, SM; Skolnick, P1
Katz, RJ; Wagner, JA1
File, SE; Pellow, S5
Braun, MR; Cason, CR; Devaraju, SL; Eggers, MW; Greene, TL; June, HL; Leveige, T; Murphy, JM; Torres, L; Williams, JA1
Davies, MF; Loew, GH; Pryor, GT; Uyeno, ET1
Gerhardt, S; Liebman, JM1
Harris, C; Lal, H1
Crawley, JN; Glowa, JR; Paul, SM; Schwartz, RD; Skolnick, P; Suzdak, PD1
Sanger, DJ1

Reviews

1 review(s) available for 2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one and Anxiety

ArticleYear
Anxioselective anxiolytics.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:5

    Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety; Azabicyclo Compounds; Benzodiazepines; Brain Chemistry; Drug Interactions; Etazolate; gamma-Aminobutyric Acid; Humans; Molecular Weight; Piperazines; Pyrazoles; Pyridazines; Quinolines; Receptors, Cell Surface; Receptors, GABA-A; Structure-Activity Relationship

1983

Other Studies

17 other study(ies) available for 2-phenylpyrazolo(4,3-c)quinolin-3(5h)-one and Anxiety

ArticleYear
Antagonism by NOS inhibition of the behavioral effects of benzodiazepine and GABAA receptor agonists in the mouse elevated plus-maze.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2004, Volume: 29, Issue:8

    Topics: Animals; Anxiety; Behavior, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; GABA Agonists; GABA-A Receptor Agonists; Injections, Intraventricular; Isoxazoles; Male; Mice; Nitric Oxide Synthase; Nitroarginine; Pyrazoles; Pyridazines

2004
Quinolines and anxiety: anxiogenic effects of CGS 8216 and partial anxiolytic profile of PK 9084.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Diazepam; Humans; Male; Motor Activity; Pyrazoles; Quinolines; Rats; Social Behavior

1983
Absence of intrinsic antagonist actions of benzodiazepine antagonists on an exploratory model of anxiety in the mouse.
    Neuropharmacology, 1984, Volume: 23, Issue:5

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepinones; Carbolines; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Flumazenil; Humans; Male; Mice; Pyrazoles

1984
Interactions of ethyl-beta-carboline-3-carboxylate and Ro 15-1788 with CGS 8216 in an animal model of anxiety.
    Neuroscience letters, 1983, Aug-19, Volume: 39, Issue:1

    Topics: Animals; Anxiety; Benzodiazepinones; Carbolines; Disease Models, Animal; Drug Interactions; Flumazenil; Humans; Indoles; Male; Pyrazoles; Rats; Receptors, Cell Surface; Receptors, GABA-A; Social Behavior

1983
New concepts in the neurobiology of anxiety.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:11 Pt 2

    Topics: Animals; Anxiety; Barbiturates; Behavior; Behavior, Animal; Benzodiazepines; Benzodiazepinones; Carbolines; Central Nervous System; Flumazenil; Humans; Macaca mulatta; Pyrazoles; Receptors, Cell Surface; Receptors, GABA-A

1983
Anxiogenic action of benzodiazepine antagonists Ro 15-1788 and CGS 8216 in the rat.
    Neuroscience letters, 1984, Aug-10, Volume: 48, Issue:3

    Topics: Animals; Anxiety; Benzodiazepines; Benzodiazepinones; Convulsants; Dose-Response Relationship, Drug; Flumazenil; Humans; Male; Pyrazoles; Rats; Rats, Inbred Strains

1984
The anxiogenic action of FG 7142 in the social interaction test is reversed by chlordiazepoxide and Ro 15-1788 but not by CGS 8216.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 271, Issue:2

    Topics: Animals; Anxiety; Benzodiazepinones; Carbolines; Chlordiazepoxide; Convulsants; Flumazenil; Humans; Indoles; Male; Motor Activity; Pyrazoles; Rats; Social Behavior

1984
Benzodiazepine receptor antagonists modulate the actions of ethanol in alcohol-preferring and -nonpreferring rats.
    European journal of pharmacology, 1998, Jan-26, Volume: 342, Issue:2-3

    Topics: Alcohol Drinking; Animals; Anxiety; Carbolines; Central Nervous System Depressants; Dose-Response Relationship, Drug; Eating; Ethanol; Female; GABA Antagonists; GABA-A Receptor Antagonists; Motor Activity; Pyrazoles; Rats

1998
Selective effect on punished versus unpunished responding in a conflict test as the criterion for anxiogenic activity.
    Life sciences, 1990, Volume: 47, Issue:15

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Carbolines; Conflict, Psychological; Electroshock; Male; Pentylenetetrazole; Punishment; Pyrazoles; Rats; Rats, Inbred Strains; Water Deprivation

1990
Self-regulation of ICSS duration: effects of anxiogenic substances, benzodiazepine antagonists and antidepressants.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Benzodiazepinones; Caffeine; Carbolines; Conditioning, Operant; Convulsants; Flumazenil; Humans; Male; Pentylenetetrazole; Pyrazoles; Rats; Rats, Inbred F344; Self Stimulation; Time Factors

1985
Interoceptive stimuli produced by an anxiogenic drug are mimicked by benzodiazepine antagonists in rats pretreated with isoniazid.
    Neuropharmacology, 1985, Volume: 24, Issue:7

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepinones; Brain Chemistry; Convulsants; Discrimination, Psychological; Flumazenil; gamma-Aminobutyric Acid; Humans; Isoniazid; Male; Pentobarbital; Pentylenetetrazole; Pyrazoles; Rats

1985
Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Benzodiazepinones; Buspirone; Carbolines; Convulsants; Exploratory Behavior; Flumazenil; Male; Pyrazoles; Pyridazines; Pyrimidines; Quinolines; Rats

1986
The anxiogenic action of RO 5-4864 in the social interaction test: effect of chlordiazepoxide, RO 15-1788 and CGS 8216.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 328, Issue:3

    Topics: Animals; Anxiety; Benzodiazepinones; Chlordiazepoxide; Convulsants; Drug Interactions; Flumazenil; Humans; Male; Motor Activity; Pyrazoles; Rats; Receptors, GABA-A; Social Behavior

1985
The effects of putative anxiogenic compounds (FG 7142, CGS 8216 and Ro 15-1788) on the rat corticosterone response.
    Physiology & behavior, 1985, Volume: 35, Issue:4

    Topics: Animals; Anxiety; Benzodiazepinones; Carbolines; Corticosterone; Flumazenil; Male; Pyrazoles; Rats; Receptors, GABA-A; Stress, Psychological

1985
A selective imidazobenzodiazepine antagonist of ethanol in the rat.
    Science (New York, N.Y.), 1986, Dec-05, Volume: 234, Issue:4781

    Topics: Animals; Anxiety; Azides; Benzodiazepines; Chlorides; Ethanol; Flumazenil; Male; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes

1986
Investigation of the actions of the benzodiazepine antagonists Ro 15-1788 and CGS 8216 using the schedule-controlled behavior of rats.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:3

    Topics: Animals; Anxiety; Behavior, Animal; Benzodiazepines; Diazepam; Drug Interactions; Flumazenil; Male; Pyrazoles; Pyridines; Rats; Rats, Inbred Strains; Zolpidem

1986
Chlordiazepoxide enhances the anxiogenic action of CGS 8216 in the social interaction test: evidence for benzodiazepine withdrawal?
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:1

    Topics: Animals; Anxiety; Benzodiazepinones; Carbolines; Chlordiazepoxide; Flumazenil; Humans; Male; Pyrazoles; Rats; Social Behavior; Species Specificity; Substance Withdrawal Syndrome

1985