2-phenylglycine has been researched along with Parkinson Disease in 1 studies
2-phenylglycine: RN given refers to cpd without isomeric designation; structure
alpha-phenylglycine : An amino acid with a structure in which a phenyl ring is bonded to the alpha-carbon of glycine.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The oral bioavailability of D-phenylglycine-L-dopa was 31." | 1.36 | Evidence of D-phenylglycine as delivering tool for improving L-dopa absorption. ( Fan, YB; Lu, HH; Tsai, MC; Tsai, TH; Wang, CL; Wang, HP, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, CL | 1 |
| Fan, YB | 1 |
| Lu, HH | 1 |
| Tsai, TH | 1 |
| Tsai, MC | 1 |
| Wang, HP | 1 |
1 other study available for 2-phenylglycine and Parkinson Disease
| Article | Year |
|---|---|
Evidence of D-phenylglycine as delivering tool for improving L-dopa absorption.
Topics: Animals; Biological Availability; Chromatography, High Pressure Liquid; Dopamine; Drug Carriers; Gly | 2010 |