2-oxo-3-methylvalerate has been researched along with Nerve Degeneration in 1 studies
alpha-keto-beta-methylvaleric acid: RN given refers to parent cpd
3-methyl-2-oxovaleric acid : A 2-oxo monocarboxylic acid that is valeric acid carrying oxo- and methyl substituents at C-2 and C-3, respectively. An alpha-keto acid analogue and metabolite of isoleucine in man, animals and bacteria. Used as a clinical marker for maple syrup urine disease (MSUD).
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pessoa-Pureur, R | 1 |
| Funchal, C | 1 |
| de Lima Pelaez, P | 1 |
| Vivian, L | 1 |
| Oliveira Loureiro, S | 1 |
| de Freitas Miranda, R | 1 |
| Wajner, M | 1 |
1 other study available for 2-oxo-3-methylvalerate and Nerve Degeneration
| Article | Year |
|---|---|
Effect of the branched-chain alpha-ketoacids accumulating in maple syrup urine disease on the high molecular weight neurofilament subunit (NF-H) in rat cerebral cortex.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Cytoskeleton; Dose-Response Relationship, Drug; Hemiterp | 2002 |