Page last updated: 2024-08-24

2-oxindole and Osteosarcoma

2-oxindole has been researched along with Osteosarcoma in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bernard, D; Carry, JC; Deschamps, JR; Ferey, V; Li, X; Liu, L; Lu, J; McEachern, D; Ochsenbein, P; Sun, D; Sun, W; Wang, S; Yu, S; Zhao, Y1
Aguilar, A; Bernard, D; Deschamps, JR; Liu, L; Lu, J; McEachern, D; Sun, W; Wang, S1

Other Studies

2 other study(ies) available for 2-oxindole and Osteosarcoma

ArticleYear
Diastereomeric spirooxindoles as highly potent and efficacious MDM2 inhibitors.
    Journal of the American Chemical Society, 2013, May-15, Volume: 135, Issue:19

    Topics: Animals; Antineoplastic Agents; Bone and Bones; Bone Neoplasms; Cell Line, Tumor; Cyclization; Humans; Indoles; Mice, SCID; Models, Molecular; Osteosarcoma; Oxindoles; Proto-Oncogene Proteins c-mdm2; Spiro Compounds; Stereoisomerism

2013
Design of chemically stable, potent, and efficacious MDM2 inhibitors that exploit the retro-mannich ring-opening-cyclization reaction mechanism in spiro-oxindoles.
    Journal of medicinal chemistry, 2014, Dec-26, Volume: 57, Issue:24

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cell Proliferation; Cyclization; Drug Design; Humans; Indoles; Mice; Mice, SCID; Models, Molecular; Molecular Structure; Osteosarcoma; Oxindoles; Proto-Oncogene Proteins c-mdm2; Spiro Compounds; Structure-Activity Relationship; Tumor Cells, Cultured

2014