Compounds > 2-oxindole
Page last updated: 2024-08-24

2-oxindole and Breast Neoplasms

2-oxindole has been researched along with Breast Neoplasms in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's0 (0.00)29.6817
2010's9 (75.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Abdel-Aziz, AK; Abouzid, KAM; Dokla, EME; Mahmoud, AH; McPhillie, MJ; Milik, SN; Minucci, S; Saadeldin, MK1
Huang, J; Li, H; Liu, X; Xu, Y; Xue, M; Yuan, J; Zhao, X; Zhao, Z; Zhong, Y1
Abdel-Aziz, HA; Alsherbiny, MA; Aly, MH; Eldehna, WM; Fares, M; Ghabbour, HA; Ibrahim, HS1
Gong, P; Lv, Y; Wang, S; Zhang, G; Zhang, N; Zhao, Y1
Han, W; Huang, J; Jiang, J; Ruhan, A; Wang, J; Yao, D1
Agalou, A; Argyros, O; Asvos, X; Beis, D; Davos, CH; Fokas, D; Karampelas, T; Papakyriakou, A; Tamvakopoulos, C; Varela, A1
Adhikari, S; Banerjee, R; Ganguly, A; Ghosh, A; Pal, A; Rathore, B; Yousuf, M1
Bishnoi, AK; Dwivedi, A; Gupta, G; Konwar, R; Kumar, A; Kumar, S; Saini, KS; Saxena, R1
Abdelhamid, IA; Ahmed, AG; Attia, YM; Ghozlan, SA; Mohamed, MF; Shouman, SA1
Agarwal, R; Dutta, PK; Hati, S; Sen, S; Singh, A; Singh, S; Srinivasan, R; Tripathy, S1
Andricopulo, AD; Carneiro, JW; Dias, LC; Krogh, R; Lanznaster, M; Pinto, AC; Ribeiro, NM; Silva, BV; Vargas, MD1
Hull-Campbell, NE; Kent, LL; Lau, T; Nori, M; Thompson, SA; Wu, JC1

Other Studies

12 other study(ies) available for 2-oxindole and Breast Neoplasms

ArticleYear
Indolin-2-one derivatives as selective Aurora B kinase inhibitors targeting breast cancer.
    Bioorganic chemistry, 2021, Volume: 117

    Topics: Antineoplastic Agents; Aurora Kinase B; Breast Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Indoles; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured

2021
Substituted indolin-2-ones as p90 ribosomal S6 protein kinase 2 (RSK2) inhibitors: Molecular docking simulation and structure-activity relationship analysis.
    Bioorganic & medicinal chemistry, 2013, Apr-01, Volume: 21, Issue:7

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Indoles; Male; Molecular Docking Simulation; Prostatic Neoplasms; Protein Kinase Inhibitors; Ribosomal Protein S6 Kinases, 90-kDa; Structure-Activity Relationship

2013
Synthesis and Cytotoxic Activity of Biphenylurea Derivatives Containing Indolin-2-one Moieties.
    Molecules (Basel, Switzerland), 2016, Jun-10, Volume: 21, Issue:6

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Doxorubicin; Drug Screening Assays, Antitumor; Female; Humans; Indoles; Male; MCF-7 Cells; Prostatic Neoplasms; Rhodamines; Structure-Activity Relationship; Urea

2016
Design, synthesis and biological evaluation of novel 4-thiazolidinones containing indolin-2-one moiety as potential antitumor agent.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:8

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Design; Drug Screening Assays, Antitumor; Female; Fibroblasts; Humans; Indoles; Inhibitory Concentration 50; Liver Neoplasms; Lung Neoplasms; Pyrroles; Sunitinib; Thiazolidines

2011
Design, synthesis and biological evaluation of 2-indolinone derivatives as PAK1 inhibitors in MDA-MB-231 cells.
    Bioorganic & medicinal chemistry letters, 2020, 09-01, Volume: 30, Issue:17

    Topics: Apoptosis; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Drug Design; Female; Humans; Molecular Docking Simulation; Oxindoles; p21-Activated Kinases; Protein Binding; Protein Kinase Inhibitors; Structure-Activity Relationship; Thermodynamics

2020
Targeting of the breast cancer microenvironment with a potent and linkable oxindole based antiangiogenic small molecule.
    Oncotarget, 2017, Jun-06, Volume: 8, Issue:23

    Topics: Angiogenesis Inhibitors; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Mice; Mice, Inbred C57BL; Mice, SCID; Neoplasms, Experimental; Oxindoles; Pyrroles; Sunitinib; Tumor Burden; Tumor Microenvironment; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays

2017
Bis-arylidene oxindoles as anti-breast-cancer agents acting via the estrogen receptor.
    ChemMedChem, 2014, Volume: 9, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Cell Survival; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Down-Regulation; Drug Screening Assays, Antitumor; Female; HEK293 Cells; Humans; Indoles; MCF-7 Cells; Molecular Structure; Oxindoles; Receptors, Estrogen; Structure-Activity Relationship

2014
Design and synthesis of new bioisosteres of spirooxindoles (MI-63/219) as anti-breast cancer agents.
    Bioorganic & medicinal chemistry, 2015, Feb-15, Volume: 23, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Cell Line, Tumor; Drug Design; Female; Humans; Indoles; Mice, Nude; Oxindoles; Protein Interaction Maps; Proto-Oncogene Proteins c-mdm2; Spiro Compounds; Tumor Suppressor Protein p53

2015
Cytotoxic and antimicrobial evaluations of novel apoptotic and anti-angiogenic spiro cyclic 2-oxindole derivatives of 2-amino-tetrahydroquinolin-5-one.
    Archiv der Pharmazie, 2015, Volume: 348, Issue:2

    Topics: Angiogenesis Inhibitors; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Caspase 9; Cell Proliferation; Disk Diffusion Antimicrobial Tests; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Design; Hep G2 Cells; Humans; Indoles; MCF-7 Cells; Molecular Structure; Neovascularization, Pathologic; Oxindoles; Quinolones; Signal Transduction; Structure-Activity Relationship; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A

2015
Spiro[pyrrolidine-3, 3ยด-oxindole] as potent anti-breast cancer compounds: Their design, synthesis, biological evaluation and cellular target identification.
    Scientific reports, 2016, 08-30, Volume: 6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Chlorocebus aethiops; COS Cells; Drug Design; Female; Humans; Indoles; MCF-7 Cells; Molecular Dynamics Simulation; Molecular Structure; Oxindoles; Pyrrolidines; Spiro Compounds

2016
Synthesis, electrochemical studies and anticancer activity of ferrocenyl oxindoles.
    Dalton transactions (Cambridge, England : 2003), 2010, Aug-21, Volume: 39, Issue:31

    Topics: Antineoplastic Agents; Breast Neoplasms; Catalysis; Cell Line, Tumor; Electrochemical Techniques; Female; Ferrous Compounds; Humans; Indoles; Isomerism; Metallocenes; Morpholines; Oxidation-Reduction; Oxindoles

2010
Characterization of novel inhibitors of cyclin-dependent kinases.
    Biochemical and biophysical research communications, 1999, Jul-14, Volume: 260, Issue:3

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Benzoic Acid; Blotting, Western; Breast Neoplasms; Cell Division; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Indoles; Inhibitory Concentration 50; Kinetics; Oxindoles; Proto-Oncogene Proteins; Retinoblastoma Protein; Substrate Specificity; Tumor Cells, Cultured; Urea

1999