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2-n-propyl-4-pentynoic acid and Pregnancy

2-n-propyl-4-pentynoic acid has been researched along with Pregnancy in 2 studies

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elmazar, MM; Hauck, RS; Nau, H; Plum, C1
Elmazar, MM; Hauck, RS; Nau, H1

Other Studies

2 other study(ies) available for 2-n-propyl-4-pentynoic acid and Pregnancy

ArticleYear
The enantioselective teratogenicity of 2-n-propyl-4-pentynoic acid (4-yn-VPA) is due to stereoselective intrinsic activity and not differences in pharmacokinetics.
    Toxicology letters, 1992, Volume: 60, Issue:2

    Topics: Animals; Anticonvulsants; Chromatography, Gas; Embryo, Mammalian; Fatty Acids, Unsaturated; Female; Injections, Intraperitoneal; Maternal-Fetal Exchange; Mice; Pregnancy; Stereoisomerism; Structure-Activity Relationship; Teratogens

1992
On the development of alternative antiepileptic drugs. Lack of enantioselectivity of the anticonvulsant activity, in contrast to teratogenicity, of 2-n-propyl-4-pentenoic acid and 2-n-propyl-4-pentynoic acid, analogues of the anticonvulsant drug valproic
    Die Naturwissenschaften, 1991, Volume: 78, Issue:6

    Topics: Animals; Anticonvulsants; Drug Design; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Female; Mice; Mice, Inbred Strains; Pentylenetetrazole; Pregnancy; Regression Analysis; Seizures; Stereoisomerism; Teratogens; Valproic Acid

1991