2-methylcitric acid has been researched along with Pregnancy in 6 studies
2-methylcitric acid: RN given refers to parent cpd
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methylmalonic aciduria is an inborn error of metabolism characterized by accumulation of methylmalonate (MMA), propionate and 2-methylcitrate (2-MCA) in body fluids." | 1.39 | Brain damage in methylmalonic aciduria: 2-methylcitrate induces cerebral ammonium accumulation and apoptosis in 3D organotypic brain cell cultures. ( Ballhausen, D; Bonafé, L; Braissant, O; Henry, H; Jafari, P; Zavadakova, P, 2013) |
| " The pathomechanisms involved are still unknown, a contribution of toxic organic acids, in particular MMA, has been suggested." | 1.31 | Neurodegeneration in methylmalonic aciduria involves inhibition of complex II and the tricarboxylic acid cycle, and synergistically acting excitotoxicity. ( Farkas, LM; Feyh, P; Hinz, A; Hoffmann, GF; Hörster, F; Kölker, S; Mayatepek, E; Okun, JG; Sauer, S; Unsicker, K, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jafari, P | 1 |
| Braissant, O | 1 |
| Zavadakova, P | 1 |
| Henry, H | 1 |
| Bonafé, L | 1 |
| Ballhausen, D | 1 |
| Campbell, CD | 1 |
| Ganesh, J | 1 |
| Ficicioglu, C | 1 |
| Zhang, Y | 1 |
| Yang, YL | 1 |
| Hasegawa, Y | 1 |
| Yamaguchi, S | 1 |
| Shi, CY | 1 |
| Song, JQ | 1 |
| Sayami, S | 1 |
| Liu, P | 1 |
| Yan, R | 1 |
| Dong, JH | 1 |
| Qin, J | 1 |
| Dhondt, JL | 1 |
| Farriaux, JP | 1 |
| Amedee Manesme, O | 1 |
| Cartigny, B | 1 |
| Sweetman, L | 1 |
| Duran, M | 1 |
| Okun, JG | 1 |
| Hörster, F | 1 |
| Farkas, LM | 1 |
| Feyh, P | 1 |
| Hinz, A | 1 |
| Sauer, S | 1 |
| Hoffmann, GF | 1 |
| Unsicker, K | 1 |
| Mayatepek, E | 1 |
| Kölker, S | 1 |
| Kretschmer, RE | 1 |
| Bachmann, C | 1 |
6 other studies available for 2-methylcitric acid and Pregnancy
| Article | Year |
|---|---|
Brain damage in methylmalonic aciduria: 2-methylcitrate induces cerebral ammonium accumulation and apoptosis in 3D organotypic brain cell cultures.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Apoptosis; Blotting, Western; Brain; Caspase 3; Cells | 2013 |
Two newborns with nutritional vitamin B12 deficiency: challenges in newborn screening for vitamin B12 deficiency.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Anemia, Pernicious; Autoimmune Diseases; Biomarkers; Carnitine; | 2005 |
Prenatal diagnosis of methylmalonic aciduria by analysis of organic acids and total homocysteine in amniotic fluid.
Topics: Amniotic Fluid; Carnitine; Citrates; Female; Gas Chromatography-Mass Spectrometry; Homocysteine; Hum | 2008 |
Antenatal diagnosis of propionic acidaemia by methylcitrate determination.
Topics: Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Carbon-Carbon Ligases; Citrates; Female; Human | 1981 |
Neurodegeneration in methylmalonic aciduria involves inhibition of complex II and the tricarboxylic acid cycle, and synergistically acting excitotoxicity.
Topics: Animals; Cells, Cultured; Citrates; Citric Acid Cycle; Corpus Striatum; Electron Transport Complex I | 2002 |
Methylcitric acid determination in amniotic fluid by electron-impact mass fragmentography.
Topics: Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Citrates; Female; Gas Chromatography-Mass Spec | 1988 |