2-methylcitric acid has been researched along with Brain Injuries in 1 studies
2-methylcitric acid: RN given refers to parent cpd
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A dose-response relationship was observed for all effects." | 1.43 | Ammonium accumulation is a primary effect of 2-methylcitrate exposure in an in vitro model for brain damage in methylmalonic aciduria. ( Ballhausen, D; Braissant, O; Cudré-Cung, HP; do Vale-Pereira, S; Henry, H; Ivanisevic, J; Remacle, N; Tavel, D; Zavadakova, P, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cudré-Cung, HP | 1 |
| Zavadakova, P | 1 |
| do Vale-Pereira, S | 1 |
| Remacle, N | 1 |
| Henry, H | 1 |
| Ivanisevic, J | 1 |
| Tavel, D | 1 |
| Braissant, O | 1 |
| Ballhausen, D | 1 |
1 other study available for 2-methylcitric acid and Brain Injuries
| Article | Year |
|---|---|
Ammonium accumulation is a primary effect of 2-methylcitrate exposure in an in vitro model for brain damage in methylmalonic aciduria.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Metabolism, Inborn Errors; Ammonium Compounds; Animals; | 2016 |