2-methyladenosine and Tuberculosis

2-methyladenosine has been researched along with Tuberculosis* in 1 studies

Other Studies

1 other study(ies) available for 2-methyladenosine and Tuberculosis

Article	Year
6-Oxo and 6-thio purine analogs as antimycobacterial agents. Bioorganic & medicinal chemistry, 2013, Apr-01, Volume: 21, Issue:7 6-Oxo and 6-thio analogs of purine were prepared based on the initial activity screening of a small, diverse purine library against Mycobacterium tuberculosis (Mtb). Certain 6-oxo and 6-thio-substituted purine analogs described herein showed moderate to good inhibitory activity. N(9)-substitution apparently enhances the anti-mycobacterial activity in the purine series described herein. Several 2-amino and 2-chloro purine analogs were also synthesized that showed moderate inhibitory activity against Mtb. Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Humans; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Purines; Sulfhydryl Compounds; Tuberculosis; Vero Cells	2013

Article

Year

6-Oxo and 6-thio purine analogs as antimycobacterial agents.

Bioorganic & medicinal chemistry, 2013, Apr-01, Volume: 21, Issue:7

6-Oxo and 6-thio analogs of purine were prepared based on the initial activity screening of a small, diverse purine library against Mycobacterium tuberculosis (Mtb). Certain 6-oxo and 6-thio-substituted purine analogs described herein showed moderate to good inhibitory activity. N(9)-substitution apparently enhances the anti-mycobacterial activity in the purine series described herein. Several 2-amino and 2-chloro purine analogs were also synthesized that showed moderate inhibitory activity against Mtb.

Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Humans; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Purines; Sulfhydryl Compounds; Tuberculosis; Vero Cells

2013