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2-methyl-5-ht and Bronchial Spasm

2-methyl-5-ht has been researched along with Bronchial Spasm in 1 studies

2-methyl-5-HT: M-receptor agonist

Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.

Research Excerpts

ExcerptRelevanceReference
" The NK1 antagonist (+/-)-CP96345 was found to cause, at a maximally tolerated dose of 9 mumol/kg, an approximate 10-fold rightward shift of the dose-response curves for selective NK1 agonists substance P (SP), [Sar9,Met(O2)11]SP and Ac-[Arg6,Sar9,Met(O2)11]SP6-11 without altering responses to selective NK2 agonists neurokinin A (NKA), [Nle10]NKA4-10 or [beta-Ala8]NKA4-10."1.29Differential blockade by tachykinin NK1 and NK2 receptor antagonists of bronchoconstriction induced by direct-acting agonists and the indirect-acting mimetics capsaicin, serotonin and 2-methyl-serotonin in the anesthetized guinea pig. ( Buckner, CK; Campbell, J; Dea, D; Krell, RD; Lengel, D; Liberati, N; Miller, S; Shenvi, A; Stinson-Fisher, C, 1993)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buckner, CK1
Liberati, N1
Dea, D1
Lengel, D1
Stinson-Fisher, C1
Campbell, J1
Miller, S1
Shenvi, A1
Krell, RD1

Other Studies

1 other study available for 2-methyl-5-ht and Bronchial Spasm

ArticleYear
Differential blockade by tachykinin NK1 and NK2 receptor antagonists of bronchoconstriction induced by direct-acting agonists and the indirect-acting mimetics capsaicin, serotonin and 2-methyl-serotonin in the anesthetized guinea pig.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: Amino Acid Sequence; Anesthesia; Animals; Benzamides; Biphenyl Compounds; Bronchial Spasm; Bronchoco

1993