2-methyl-4(3h)-quinazolinone has been researched along with Bacterial-Infections* in 1 studies
1 other study(ies) available for 2-methyl-4(3h)-quinazolinone and Bacterial-Infections
| Article | Year |
|---|---|
Palladium(II) complexes as biologically potent metallo-drugs: synthesis, spectral characterization, DNA interaction studies and antibacterial activity.
Four novel mononuclear Pd(II) complexes have been synthesized with the biologically active Schiff base ligands (L1-L4) derived from 3-amino-2-methyl-4(3H)-quinazolinone. The structure of the complexes has been proposed by elemental analysis, molar conductance, IR, (1)H NMR, mass, UV-Vis spectrometric and thermal studies. The investigation of interaction of the complexes with calf thymus DNA (CT-DNA) has been performed with absorption and fluorescence spectroscopic studies. The nuclease activity was done using pUC19 supercoiled DNA by gel-electrophoresis. All the ligands and their Pd(II) complexes have also been screened for their antibacterial activity by discolor diffusion technique. Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cattle; Coordination Complexes; DNA; DNA, Circular; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Palladium; Plasmids; Quinazolinones; Schiff Bases; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 2013 |