2-methoxyestradiol has been researched along with Sclerosis, Systemic in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, M; Liu, C; Lu, J; Zhou, X; Zhu, L | 2 |
| Li, M; Song, Y; Zhu, L | 1 |
3 other study(ies) available for 2-methoxyestradiol and Sclerosis, Systemic
| Article | Year |
|---|---|
2-Methoxyestradiol inhibits hypoxia-induced scleroderma fibroblast collagen synthesis by phosphatidylinositol 3-kinase/Akt/mTOR signalling.
Topics: 2-Methoxyestradiol; Cell Proliferation; Cells, Cultured; Collagen Type I; Connective Tissue Growth Factor; Estradiol; Fibroblasts; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Proto-Oncogene Proteins c-akt; RNA; Scleroderma, Systemic; Signal Transduction; Skin; TOR Serine-Threonine Kinases; Tubulin Modulators | 2018 |
Autophagy mediates 2-methoxyestradiol-inhibited scleroderma collagen synthesis and endothelial-to-mesenchymal transition induced by hypoxia.
Topics: 2-Methoxyestradiol; Actins; Autophagy; Cells, Cultured; Collagen Type I; Connective Tissue Growth Factor; Epithelial-Mesenchymal Transition; Fibroblasts; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia; Platelet Endothelial Cell Adhesion Molecule-1; Scleroderma, Systemic; Skin; Vimentin | 2019 |
2-Methoxyestradiol inhibits bleomycin-induced systemic sclerosis through suppression of fibroblast activation.
Topics: 2-Methoxyestradiol; Adolescent; Adult; Animals; Bleomycin; Cell Differentiation; Cell Proliferation; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Estradiol; Female; Fibroblasts; Gene Expression Regulation; Humans; Hydroxyproline; Male; Mice; Mice, Inbred C3H; Middle Aged; RNA, Messenger; Scleroderma, Systemic | 2015 |