2-methoxyestradiol has been researched along with Pregnancy in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 7 (28.00) | 29.6817 |
| 2010's | 14 (56.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, T; Fukunaga, K; Imachi, H; Iwama, H; Kobayashi, T; Lyu, J; Murao, K; Saheki, T; Sato, S; Zhang, G | 1 |
| Kanasaki, K; Kanasaki, M; Kim, H; Kitada, M; Koya, D; Kudoh, S; Li, J; Srivastava, SP; Takeda, S; Ueki, N; Xu, L; Yang, F | 1 |
| Chen, M; Chen, Q; Hu, Z; Wan, J; Yin, Y; Zeng, K; Zhao, M | 1 |
| España-Perrot, PP; Illanes, SE; Norwitz, ER; Perez-Sepulveda, A | 1 |
| Bonacasa, B; Bosch, V; Delgado, JL; Fenoy, FJ; Hernández, I; Hernández, M; Mendiola, J; Pertegal, M; Salom, MG | 1 |
| Lee, DK; Nevo, O | 1 |
| Chang, X; Chen, X; Duan, T; Shen, Z; Wang, K; Wu, Y; Ying, H; Zheng, J; Zhou, J; Zhou, Q | 1 |
| Bonacasa, B; Bosch, V; Corno, A; Delgado, JL; Fenoy, FJ; Hernández, I; Hernández, M; López, B; Mendiola, J; Pertegal, M | 1 |
| Dragun, D; Haase-Fielitz, A | 1 |
| Banerjee, S; Chambers, AE; Randeva, H | 1 |
| Kalluri, R; Kanasaki, K; Lee, SB; McElrath, TF; Shenoy, VK; Whitesides, GM; Wong, AP; Xu, Y | 1 |
| Barnes, CM; Folkman, J; Hansen, AR; McElrath, TF | 1 |
| Kalluri, R; Kanasaki, K; Shenoy, V | 1 |
| Albayrak, S; Kapur, A; Magness, RR; Salama, SA; Salih, SM | 1 |
| Gkagtzis, DC; Hadjichristodoulou, CS; Koukoulis, GN; Tsakalof, AK | 1 |
| Figueroa-Diesel, H; Galaz, J; Illanes, SE; Larraín, R; Michea, L; Nien, JK; Pérez-Sepúlveda, A; Serra, R; Torres, MJ; Valenzuela, FJ | 1 |
| Cho, GJ; Kim, HJ; Oh, MJ; Seol, HJ | 1 |
| FRANDSEN, VA | 1 |
| Calvo, A; Catena, R; Chandramouli, GV; Charles, R; Desprez, PY; Green, JE; Hager, GL; Huh, JI; LaVallee, TM; Qiu, TH; Wiench, M | 1 |
| Eichenlaub-Ritter, U; Shen, Y; Sorensen, R; Tinneberg, HR; Vogt, E; Winterscheidt, U | 1 |
| Croxatto, HB; Cuevas, CA; Navarrete-Gómez, PA; Orihuela, PA; Parada-Bustamante, A; Ríos, M; Velasquez, LA; Villalón, MJ | 1 |
| Ahmad, S; Augustin, HG; Folkman, J; Gattone, VH; Hamano, Y; Kalluri, R; Kanasaki, K; Palmsten, K; Parry, S; Strauss, JF; Sugimoto, H; Xie, L | 1 |
| Hitchins, DJ; Orsini, MW; Sholl, SA | 1 |
| Arscott, PL; Baker, JR; Bretz, JD; Koenig, RJ; Myc, A; Wang, SH | 1 |
| Davis, DL; Zhang, Z | 1 |
3 review(s) available for 2-methoxyestradiol and Pregnancy
| Article | Year |
|---|---|
Metabolic pathways involved in 2-methoxyestradiol synthesis and their role in preeclampsia.
Topics: 2-Methoxyestradiol; Animals; Aromatase; Biomarkers; Catechol O-Methyltransferase; Estradiol; Female; Humans; Pre-Eclampsia; Pregnancy; Risk Factors; Signal Transduction; Up-Regulation | 2013 |
Low catechol-O-methyltransferase and 2-methoxyestradiol in preeclampsia: more than a unifying hypothesis.
Topics: 2-Methoxyestradiol; Animals; Catechol O-Methyltransferase; Endothelium, Vascular; Estradiol; Female; Humans; Mice; Models, Biological; Neovascularization, Pathologic; Pre-Eclampsia; Pregnancy; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2009 |
Pre-eclampsia: connecting angiogenic and metabolic pathways.
Topics: 2-Methoxyestradiol; Catechol O-Methyltransferase; Estradiol; Female; Humans; Neovascularization, Pathologic; Pre-Eclampsia; Pregnancy | 2010 |
22 other study(ies) available for 2-methoxyestradiol and Pregnancy
| Article | Year |
|---|---|
Treatment with 2-methoxyestradiol increases endothelial nitric oxide synthase activity via scavenger receptor class BI in human umbilical vein endothelial cells.
Topics: 2-Methoxyestradiol; Blotting, Western; Chromatin Immunoprecipitation; Female; Human Umbilical Vein Endothelial Cells; Humans; Lipoproteins, HDL; Nitric Oxide; Nitric Oxide Synthase Type III; Pre-Eclampsia; Pregnancy | 2020 |
Deficiency in catechol-o-methyltransferase is linked to a disruption of glucose homeostasis in mice.
Topics: 2-Methoxyestradiol; Animals; Catechol O-Methyltransferase; Diet, High-Fat; Female; Glucose; Glucose Intolerance; Homeostasis; Mice; Pregnancy | 2017 |
The reduction in circulating levels of estrogen and progesterone in women with preeclampsia.
Topics: 2-Methoxyestradiol; Adult; Biomarkers; Case-Control Studies; Culture Media, Conditioned; Down-Regulation; Estradiol; Female; Fetal Growth Retardation; Humans; Hydrogen Peroxide; Placenta; Pre-Eclampsia; Pregnancy; Progesterone; Receptors, Estrogen; Receptors, Progesterone; Severity of Illness Index; Tissue Culture Techniques; Tyrosine; Young Adult | 2018 |
2-methoxyestradiol plasma levels are associated with clinical severity indices and biomarkers of preeclampsia.
Topics: 2-Methoxyestradiol; Adult; Biomarkers; Case-Control Studies; Down-Regulation; Estradiol; Female; Humans; Placenta Growth Factor; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Proteins; Pregnancy Trimester, Third; Prognosis; Prospective Studies; Severity of Illness Index; Vascular Endothelial Growth Factor Receptor-1 | 2015 |
2-Methoxyestradiol regulates VEGFR-2 and sFlt-1 expression in human placenta.
Topics: 2-Methoxyestradiol; Cells, Cultured; Estradiol; Female; Gene Expression Regulation; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Placenta; Pregnancy; Pregnancy Trimester, First; Primary Cell Culture; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2015 |
Decreased maternal serum 2-methoxyestradiol levels are associated with the development of preeclampsia.
Topics: 2-Methoxyestradiol; Adult; Catechol O-Methyltransferase; Cell Hypoxia; Cell Movement; Cell Proliferation; Estradiol; Female; Humans; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First | 2014 |
Fetal Val108/158Met catechol-O-methyltransferase (COMT) polymorphism and placental COMT activity are associated with the development of preeclampsia.
Topics: 2-Methoxyestradiol; Adult; Biomarkers; Blood Pressure; Case-Control Studies; Catechol O-Methyltransferase; Chi-Square Distribution; Estradiol; Female; Fetal Blood; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Hospitals, University; Humans; Logistic Models; Methylenetetrahydrofolate Reductase (NADPH2); Multivariate Analysis; Odds Ratio; Phenotype; Placenta; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Prospective Studies; Risk Assessment; Risk Factors; Spain | 2016 |
Mouse models for preeclampsia: disruption of redox-regulated signaling.
Topics: 2-Methoxyestradiol; Animals; Catechol O-Methyltransferase; Disease Models, Animal; Estradiol; Female; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mitochondrial Proteins; Oxidation-Reduction; Oxidative Stress; Pre-Eclampsia; Pregnancy; Signal Transduction; Superoxide Dismutase | 2009 |
Preeclampsia: 2-methoxyestradiol induces cytotrophoblast invasion and vascular development specifically under hypoxic conditions.
Topics: 2-Methoxyestradiol; Animals; Blood Vessels; Catechol O-Methyltransferase; Cell Adhesion; Cell Hypoxia; Cell Movement; Cells, Cultured; Drug Synergism; Estradiol; Female; Humans; Mice; Mice, Knockout; Neovascularization, Physiologic; Oxygen; Pre-Eclampsia; Pregnancy; Trophoblasts | 2010 |
Correlation of 2-methoxyestradiol levels in cord blood and complications of prematurity.
Topics: 2-Methoxyestradiol; Adult; Amniotic Fluid; Biomarkers; Estradiol; Female; Fetal Blood; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Maternal-Fetal Exchange; Milk, Human; Pregnancy; Reference Values; Risk Assessment; Risk Factors | 2010 |
Pregnancy ameliorates the inhibitory effects of 2-methoxyestradiol on angiogenesis in primary sheep uterine endothelial cells.
Topics: 2-Methoxyestradiol; Animals; Apoptosis; Endothelial Cells; Estradiol; Female; Microscopy, Phase-Contrast; Microtubules; Neovascularization, Physiologic; Pregnancy; Pregnancy, Animal; Sheep; Uterine Artery; Uterus | 2011 |
Development of GC-MS/MS method with programmable temperature vaporization large volume injection for monitoring of 17β-estradiol and 2-methoxyestradiol in plasma.
Topics: 2-Methoxyestradiol; Estradiol; Female; Gas Chromatography-Mass Spectrometry; Humans; Pre-Eclampsia; Pregnancy; Solid Phase Extraction; Temperature; Volatilization | 2012 |
Low 2-methoxyestradiol levels at the first trimester of pregnancy are associated with the development of pre-eclampsia.
Topics: 2-Methoxyestradiol; Adult; Case-Control Studies; Catechol O-Methyltransferase; Estradiol; Female; Genetic Predisposition to Disease; Humans; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Tubulin Modulators | 2012 |
2-methoxyoestradiol levels and placental catechol-O-methyltransferase expression in patients with late-onset preeclampsia.
Topics: 2-Methoxyestradiol; Adult; Birth Weight; Blotting, Western; Catechol O-Methyltransferase; Enzyme-Linked Immunosorbent Assay; Estradiol; Female; Gestational Age; Humans; Infant, Newborn; Placenta; Pre-Eclampsia; Pregnancy; Republic of Korea | 2013 |
The demonstration of 2-methoxyoestrone and of 2-methoxyoestradiol in human pregnancy urine.
Topics: 2-Methoxyestradiol; Estradiol; Estradiol Congeners; Estrogens; Hydroxyestrones; Pregnancy | 1959 |
2-methoxyestradiol induces mammary gland differentiation through amphiregulin-epithelial growth factor receptor-mediated signaling: molecular distinctions from the mammary gland of pregnant mice.
Topics: 2-Methoxyestradiol; Amphiregulin; Animals; Cell Differentiation; Cells, Cultured; EGF Family of Proteins; ErbB Receptors; Estradiol; Female; Gene Expression Profiling; Glycoproteins; Inhibitor of Differentiation Protein 1; Intercellular Signaling Peptides and Proteins; Mammary Glands, Animal; Mice; Mice, Inbred Strains; Milk Proteins; Pregnancy; Signal Transduction | 2007 |
2-methoxyestradiol induces spindle aberrations, chromosome congression failure, and nondisjunction in mouse oocytes.
Topics: 2-Methoxyestradiol; Aneuploidy; Animals; Cell Cycle Proteins; Chromosome Aberrations; Chromosome Segregation; Chromosomes; Dose-Response Relationship, Drug; Estradiol; Female; Fluorescent Antibody Technique; Mad2 Proteins; Meiosis; Metaphase; Mice; Nondisjunction, Genetic; Nuclear Proteins; Oocytes; Pregnancy; Spindle Apparatus; Tubulin | 2007 |
Catechol-o-methyltransferase and methoxyestradiols participate in the intraoviductal nongenomic pathway through which estradiol accelerates egg transport in cycling rats.
Topics: 2-Methoxyestradiol; Animals; Aryl Hydrocarbon Hydroxylases; Catechol O-Methyltransferase; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Egg Proteins; Estradiol; Estrogens, Catechol; Female; Gene Expression Regulation; Menstrual Cycle; Methylation; Oviducts; Ovum; Phosphorylation; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Sexual Behavior, Animal | 2007 |
Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia.
Topics: 2-Methoxyestradiol; Albumins; Animals; Blood Pressure; Catechol O-Methyltransferase; Creatinine; Disease Models, Animal; Estradiol; Female; Humans; Hypertension; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Killer Cells, Natural; Litter Size; Male; Mice; Placenta; Pre-Eclampsia; Pregnancy; Proteinuria; Vascular Endothelial Growth Factor Receptor-1 | 2008 |
Estrogen synthesis and metabolism in the hamster blastocyst, uterus and liver near the time of implantation.
Topics: 2-Methoxyestradiol; Androstenedione; Animals; Aromatase; Blastocyst; Cricetinae; Endometrium; Estradiol; Estrogens; Female; In Vitro Techniques; Liver; Mesocricetus; Microsomes; Myometrium; Pregnancy; Testosterone; Uterus | 1983 |
2-Methoxyestradiol, an endogenous estrogen metabolite, induces thyroid cell apoptosis.
Topics: 2-Methoxyestradiol; Animals; Apoptosis; Autoantigens; Cell Cycle; Cells, Cultured; Estradiol; Estrogens; Female; Humans; Iodide Peroxidase; Male; Pregnancy; Rats; Thyroid Gland; Thyroiditis, Autoimmune | 2000 |
Cell-type specific responses in prostaglandin secretion by glandular and stromal cells from pig endometrium treated with catecholestrogens, methoxyestrogens and progesterone.
Topics: 2-Methoxyestradiol; Animals; Endometrium; Estradiol; Estrogens, Catechol; Female; Pregnancy; Progesterone; Prostaglandins; Swine | 1992 |