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2-methoxyestradiol and Osteogenic Sarcoma

2-methoxyestradiol has been researched along with Osteogenic Sarcoma in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (25.00)29.6817
2010's10 (62.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Cappello, F; Daca, A; Gorska-Ponikowska, M; Kuban-Jankowska, A; Luu, HH; Marino Gammazza, A; Wierzbicka, JM; Wozniak, M; Zmijewski, MA1
Bastian, P; Gorska-Ponikowska, M; Kalinowski, L; Kmiec, Z; Kuban-Jankowska, A; Nussberger, S; Ploska, A; Zauszkiewicz-Pawlak, A; Zubrzycki, A1
Gorska-Ponikowska, M; Gorzynik-Debicka, M; Kostrzewa, T; Kuban-Jankowska, A; Przychodzen, P; Wyszkowska, R1
Bravo, D; Goyal, R; Maran, A; Shogren, KL; Yang, C; Yaszemski, MJ1
Gorska, M; Gorzynik, M; Kuban-Jankowska, A; Szkatula, M; Wozniak, M; Zmijewski, MA1
Cappello, F; Daca, A; Gorska, M; Gorzynik, M; Kuban-Jankowska, A; Lewinska, A; Marino Gammazza, A; Rzeszutek, I; Wnuk, M; Wozniak, M; Zmijewski, M1
Gorska, M; Kuban-Jankowska, A; Wozniak, M; Wyszkowska, RM1
Bravo, D; Maran, A; Sarkar, G; Shogren, KL; Wagner, ER; Yaszemski, MJ; Zuo, D1
Barone, G; Gorska-Ponikowska, M; Kuban-Jankowska, A; Lo Bosco, G; Perricone, U1
Benedikt, MB; Mahlum, EW; Maran, A; Shogren, KL; Spelsberg, TC; Subramaniam, M; Yaszemski, MJ1
Goyal, R; Maran, A; Riester, SM; Shogren, KL; Wimbauer, F; Yang, C; Yaszemski, MJ; Zhang, M1
Buenz, CM; Dadsetan, M; Lu, L; Maran, A; Shogren, KL; Yaszemski, MJ1
Gołebiewska, J; Knap, N; Rozwadowski, P; Spodnik, JH; Wakabayashi, T; Woźniak, M1
Maran, A; Shogren, KL; Turner, RT; Yaszemski, MJ1
Benedikt, M; Maran, A; Sarkar, G; Shogren, KL; Turner, RT; Yaszemski, MJ1
Kennedy, AM; Maran, A; Rickard, DJ; Sibonga, JD; Spelsberg, TC; Turner, RT; Zhang, M1

Other Studies

16 other study(ies) available for 2-methoxyestradiol and Osteogenic Sarcoma

ArticleYear
The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model.
    International journal of molecular sciences, 2020, Jan-17, Volume: 21, Issue:2

    Topics: 2-Methoxyestradiol; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzoquinones; Bone Neoplasms; Drug Interactions; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Models, Biological; Osteosarcoma

2020
Regulation of mitochondrial dynamics in 2-methoxyestradiol-mediated osteosarcoma cell death.
    Scientific reports, 2021, 01-15, Volume: 11, Issue:1

    Topics: 2-Methoxyestradiol; Apoptosis; Autophagy; bcl-2-Associated X Protein; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Dynamins; Humans; Microscopy, Electron; Mitochondria; Mitochondrial Dynamics; Osteosarcoma; Quinazolinones; Up-Regulation

2021
Anticancer Potential of Oleuropein, the Polyphenol of Olive Oil, With 2-Methoxyestradiol, Separately or in Combination, in Human Osteosarcoma Cells.
    Anticancer research, 2019, Volume: 39, Issue:3

    Topics: 2-Methoxyestradiol; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Synergism; Humans; Iridoid Glucosides; Iridoids; Olive Oil; Osteosarcoma

2019
RNA-dependent protein kinase is essential for 2-methoxyestradiol-induced autophagy in osteosarcoma cells.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: 2-Methoxyestradiol; Analysis of Variance; Autophagy; Autophagy-Related Protein 7; Blotting, Western; Cell Line, Tumor; eIF-2 Kinase; Estradiol; Humans; Immunoprecipitation; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Osteosarcoma; RNA, Small Interfering; Ubiquitin-Activating Enzymes

2013
Neuronal nitric oxide synthase induction in the antitumorigenic and neurotoxic effects of 2-methoxyestradiol.
    Molecules (Basel, Switzerland), 2014, Aug-28, Volume: 19, Issue:9

    Topics: 2-Methoxyestradiol; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Induction; Estradiol; Hippocampus; Humans; Neurons; Nitric Oxide Synthase Type I; Osteosarcoma; Oxidative Stress

2014
DNA strand breaks induced by nuclear hijacking of neuronal NOS as an anti-cancer effect of 2-methoxyestradiol.
    Oncotarget, 2015, Jun-20, Volume: 6, Issue:17

    Topics: 2-Methoxyestradiol; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cytokinesis; DNA Breaks; Estradiol; G2 Phase Cell Cycle Checkpoints; Humans; Intracellular Signaling Peptides and Proteins; M Phase Cell Cycle Checkpoints; Nitric Oxide; Nitric Oxide Synthase Type I; Osteosarcoma; Oxidative Stress; Reactive Nitrogen Species; Tumor Suppressor p53-Binding Protein 1

2015
Impact of Apparent Antagonism of Estrogen Receptor β by Fulvestrant on Anticancer Activity of 2-Methoxyestradiol.
    Anticancer research, 2016, Volume: 36, Issue:5

    Topics: 2-Methoxyestradiol; Antineoplastic Agents, Hormonal; Apoptosis; Bone Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Fulvestrant; Gene Expression Regulation, Neoplastic; Histones; Humans; Neoplasm Metastasis; Neoplasm Proteins; Osteosarcoma; Phosphorylation; Protein Processing, Post-Translational

2016
2-Methoxyestradiol-Mediated Induction of Frzb Contributes to Cell Death and Autophagy in MG63 Osteosarcoma Cells.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:6

    Topics: 2-Methoxyestradiol; Antineoplastic Agents; Autophagy; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Estradiol; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Intracellular Signaling Peptides and Proteins; Osteosarcoma; Promoter Regions, Genetic; Wnt Signaling Pathway

2017
2-methoxyestradiol impacts on amino acids-mediated metabolic reprogramming in osteosarcoma cells by its interaction with NMDA receptor.
    Journal of cellular physiology, 2017, Volume: 232, Issue:11

    Topics: 2-Methoxyestradiol; Antineoplastic Agents; Binding Sites; Bone Neoplasms; Breast Neoplasms; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Energy Metabolism; Estradiol; Female; Glycine; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Molecular Docking Simulation; Molecular Dynamics Simulation; Nerve Tissue Proteins; Nitric Oxide Synthase Type I; Osteosarcoma; Protein Binding; Protein Domains; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Structure-Activity Relationship; Time Factors; Tubulin Modulators

2017
2-methoxyestradiol-mediated anti-tumor effect increases osteoprotegerin expression in osteosarcoma cells.
    Journal of cellular biochemistry, 2010, Apr-01, Volume: 109, Issue:5

    Topics: 2-Methoxyestradiol; Alkaline Phosphatase; Animals; Cell Death; Cell Proliferation; Drug Screening Assays, Antitumor; Estradiol; Gene Expression Regulation, Neoplastic; Humans; Osteoblasts; Osteoprotegerin; Osteosarcoma; Peptides; Rats; RNA, Messenger; Transcription, Genetic

2010
Regulation of interferon pathway in 2-methoxyestradiol-treated osteosarcoma cells.
    BMC cancer, 2012, Mar-19, Volume: 12

    Topics: 2-Methoxyestradiol; Bone Neoplasms; Cell Line, Tumor; Estradiol; Eukaryotic Initiation Factor-2; Gene Expression Regulation, Neoplastic; Humans; Interferons; Osteosarcoma; Promoter Regions, Genetic; Signal Transduction; Transcription, Genetic

2012
Hydrogel-PLGA delivery system prolongs 2-methoxyestradiol-mediated anti-tumor effects in osteosarcoma cells.
    Journal of biomedical materials research. Part A, 2013, Volume: 101, Issue:9

    Topics: 2-Methoxyestradiol; Antineoplastic Agents, Hormonal; Biocompatible Materials; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Drug Delivery Systems; Estradiol; Humans; Hydrogels; Lactic Acid; Materials Testing; Microspheres; Osteosarcoma; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2013
Dual effect of 2-methoxyestradiol on cell cycle events in human osteosarcoma 143B cells.
    Acta biochimica Polonica, 2002, Volume: 49, Issue:1

    Topics: 2-Methoxyestradiol; Cell Cycle; Estradiol; Humans; Microscopy, Confocal; Microtubules; Osteosarcoma; Tubulin; Tumor Cells, Cultured

2002
Double-stranded RNA-dependent protein kinase is involved in 2-methoxyestradiol-mediated cell death of osteosarcoma cells.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2007, Volume: 22, Issue:1

    Topics: 2-Methoxyestradiol; Apoptosis; Bone Neoplasms; Cell Death; Cell Division; Cell Line, Tumor; Estradiol; Humans; Osteosarcoma; Protein Kinase Inhibitors; Protein Kinases; RNA, Double-Stranded

2007
2-methoxyestradiol-induced cell death in osteosarcoma cells is preceded by cell cycle arrest.
    Journal of cellular biochemistry, 2008, Aug-01, Volume: 104, Issue:5

    Topics: 2-Methoxyestradiol; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; eIF-2 Kinase; Estradiol; Flow Cytometry; Genes, Dominant; Humans; Ligands; Mutant Proteins; Osteosarcoma

2008
2-methoxyestradiol induces interferon gene expression and apoptosis in osteosarcoma cells.
    Bone, 2002, Volume: 30, Issue:2

    Topics: 2-Methoxyestradiol; Animals; Apoptosis; Bone Matrix; Bone Neoplasms; Cell Survival; Cytokines; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; Gene Expression Regulation, Neoplastic; Growth Substances; Humans; Interferons; Osteoblasts; Osteosarcoma; Rats; Tumor Cells, Cultured

2002