Page last updated: 2024-08-24

2-methoxyestradiol and Metastase

2-methoxyestradiol has been researched along with Metastase in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gorska, M; Kuban-Jankowska, A; Wozniak, M; Wyszkowska, RM1
Arnott, J; Hahn, NM; Hammers, H; Harrison, MR; Kim, K; Liu, G; Oh, WK; Perlman, S; Pili, R; Sidor, C; Sweeney, C; Wilding, G1
James, J; Miller, KD; Murry, DJ; Sidor, C; Sledge, GW; Storniolo, AM; Treston, AM1
Kataoka, M; Mukhopadhyay, T; Roth, JA; Schumacher, G1
Green, SJ; Gubish, ER; Lavallee, TM; Pribluda, VS; Swartz, GM; Treston, A1

Reviews

1 review(s) available for 2-methoxyestradiol and Metastase

ArticleYear
2-Methoxyestradiol: an endogenous antiangiogenic and antiproliferative drug candidate.
    Cancer metastasis reviews, 2000, Volume: 19, Issue:1-2

    Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Animals; Cell Division; Cell Line; Estradiol; Humans; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Neovascularization, Pathologic; Neovascularization, Physiologic; Tumor Cells, Cultured

2000

Trials

2 trial(s) available for 2-methoxyestradiol and Metastase

ArticleYear
A phase II study of 2-methoxyestradiol (2ME2) NanoCrystal® dispersion (NCD) in patients with taxane-refractory, metastatic castrate-resistant prostate cancer (CRPC).
    Investigational new drugs, 2011, Volume: 29, Issue:6

    Topics: 2-Methoxyestradiol; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents; Disease-Free Survival; Estradiol; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Nanoparticles; Neoplasm Metastasis; Positron-Emission Tomography; Prostatic Neoplasms; Radiopharmaceuticals; Treatment Outcome

2011
Phase I safety, pharmacokinetic and pharmacodynamic studies of 2-methoxyestradiol alone or in combination with docetaxel in patients with locally recurrent or metastatic breast cancer.
    Investigational new drugs, 2007, Volume: 25, Issue:1

    Topics: 2-Methoxyestradiol; Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Docetaxel; Drug Administration Schedule; Estradiol; Fatigue; Female; Half-Life; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Taxoids; Treatment Outcome; Tubulin Modulators; Urinalysis; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A

2007

Other Studies

2 other study(ies) available for 2-methoxyestradiol and Metastase

ArticleYear
Impact of Apparent Antagonism of Estrogen Receptor β by Fulvestrant on Anticancer Activity of 2-Methoxyestradiol.
    Anticancer research, 2016, Volume: 36, Issue:5

    Topics: 2-Methoxyestradiol; Antineoplastic Agents, Hormonal; Apoptosis; Bone Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Fulvestrant; Gene Expression Regulation, Neoplastic; Histones; Humans; Neoplasm Metastasis; Neoplasm Proteins; Osteosarcoma; Phosphorylation; Protein Processing, Post-Translational

2016
Potent antitumor activity of 2-methoxyestradiol in human pancreatic cancer cell lines.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:3

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Apoptosis; Cell Division; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Estradiol; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Pancreatic Neoplasms; Tumor Cells, Cultured

1999