Page last updated: 2024-08-24

2-methoxyestradiol and Local Neoplasm Recurrence

2-methoxyestradiol has been researched along with Local Neoplasm Recurrence in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (66.67)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Han, B; Holpuch, A; Koutras, G; Lang, J; Mallery, SR; Nieto, K; Pei, P; Santiago, B; Schwendeman, SP; Spinney, R; Tong, M; Wang, D	1
Breen, T; Matei, D; Perkins, S; Quon, C; Schilder, J; Sidor, C; Sutton, G	1
James, J; Miller, KD; Murry, DJ; Sidor, C; Sledge, GW; Storniolo, AM; Treston, AM	1

Trials

2 trial(s) available for 2-methoxyestradiol and Local Neoplasm Recurrence

Article	Year
Activity of 2 methoxyestradiol (Panzem NCD) in advanced, platinum-resistant ovarian cancer and primary peritoneal carcinomatosis: a Hoosier Oncology Group trial. Gynecologic oncology, 2009, Volume: 115, Issue:1 Topics: 2-Methoxyestradiol; Adult; Aged; Antineoplastic Agents; CA-125 Antigen; Disease-Free Survival; Drug Resistance, Neoplasm; Estradiol; Female; Humans; Hydroxyestrones; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Ovarian Neoplasms; Peritoneal Neoplasms	2009
Phase I safety, pharmacokinetic and pharmacodynamic studies of 2-methoxyestradiol alone or in combination with docetaxel in patients with locally recurrent or metastatic breast cancer. Investigational new drugs, 2007, Volume: 25, Issue:1 Topics: 2-Methoxyestradiol; Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Docetaxel; Drug Administration Schedule; Estradiol; Fatigue; Female; Half-Life; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Taxoids; Treatment Outcome; Tubulin Modulators; Urinalysis; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A	2007

Article

Year

Activity of 2 methoxyestradiol (Panzem NCD) in advanced, platinum-resistant ovarian cancer and primary peritoneal carcinomatosis: a Hoosier Oncology Group trial.

Gynecologic oncology, 2009, Volume: 115, Issue:1

Topics: 2-Methoxyestradiol; Adult; Aged; Antineoplastic Agents; CA-125 Antigen; Disease-Free Survival; Drug Resistance, Neoplasm; Estradiol; Female; Humans; Hydroxyestrones; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Ovarian Neoplasms; Peritoneal Neoplasms

2009

Phase I safety, pharmacokinetic and pharmacodynamic studies of 2-methoxyestradiol alone or in combination with docetaxel in patients with locally recurrent or metastatic breast cancer.

Investigational new drugs, 2007, Volume: 25, Issue:1

Topics: 2-Methoxyestradiol; Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Docetaxel; Drug Administration Schedule; Estradiol; Fatigue; Female; Half-Life; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Taxoids; Treatment Outcome; Tubulin Modulators; Urinalysis; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A

2007

Other Studies

1 other study(ies) available for 2-methoxyestradiol and Local Neoplasm Recurrence

Article	Year
Benefits of Multifaceted Chemopreventives in the Suppression of the Oral Squamous Cell Carcinoma (OSCC) Tumorigenic Phenotype. Cancer prevention research (Philadelphia, Pa.), 2017, Volume: 10, Issue:1 Topics: 2-Methoxyestradiol; Animals; Antibodies, Monoclonal, Humanized; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinogenesis; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line, Tumor; Estradiol; Fenretinide; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Nude; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Phenotype; Phosphorylation; Receptors, Interleukin-6; Signal Transduction; STAT3 Transcription Factor; Tumor Microenvironment; Xenograft Model Antitumor Assays	2017

Article

Year

Benefits of Multifaceted Chemopreventives in the Suppression of the Oral Squamous Cell Carcinoma (OSCC) Tumorigenic Phenotype.

Cancer prevention research (Philadelphia, Pa.), 2017, Volume: 10, Issue:1

Topics: 2-Methoxyestradiol; Animals; Antibodies, Monoclonal, Humanized; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinogenesis; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line, Tumor; Estradiol; Fenretinide; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Nude; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Phenotype; Phosphorylation; Receptors, Interleukin-6; Signal Transduction; STAT3 Transcription Factor; Tumor Microenvironment; Xenograft Model Antitumor Assays

2017