2-methoxyestradiol has been researched along with Hypoxia in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 9 (60.00) | 24.3611 |
| 2020's | 4 (26.67) | 2.80 |
| Authors | Studies |
|---|---|
| Han, JX; Kasim, V; Luo, LL; Wu, SR | 1 |
| Chen, H; Shen, Y; Zhang, Y; Zhou, X | 1 |
| Huang, N; Jiang, QG; Lin, JQ; Yan, LY; Yang, WZ; Zheng, H | 1 |
| Jones, TJ; Petruševska, G; Tofovic, SP; Zhang, X | 1 |
| Fu, C; Hao, S; Jiang, L; Li, S; Liu, Z; Lu, H; Song, J; Wu, X | 1 |
| Docherty, CK; MacLean, MR; Nilsen, M | 1 |
| Li, M; Liu, C; Lu, J; Zhou, X; Zhu, L | 1 |
| Kim, SH; Lee, GJ; Li, W; Park, BM; Yu, L | 1 |
| Chen, J; Huang, T; Huang, W; Peng, Z; Xie, C; Yu, L; Zhang, Z; Zhu, D | 1 |
| Lee, DK; Nevo, O | 1 |
| Dong, X; Jiang, H; Jiang, W; Jiang, X; Lin, H; Qiao, H; Sun, X; Zhu, H | 1 |
| Hu, G; Kang, Y; Lu, X; Wei, Y; Yan, CH; Yuan, M | 1 |
| Ahlsén, M; Ivarsson, N; Katz, A; Ma, J; Ren, JM; Sandström, M; Westerblad, H; Zhang, SJ; Zhu, H | 1 |
| Fukuoka, M; Kinuya, S; Michigishi, T; Mori, H; Shiba, K; Shuke, N; Tonami, N; Watanabe, N; Yokoyama, K | 1 |
| Ahmad, S; Augustin, HG; Folkman, J; Gattone, VH; Hamano, Y; Kalluri, R; Kanasaki, K; Palmsten, K; Parry, S; Strauss, JF; Sugimoto, H; Xie, L | 1 |
15 other study(ies) available for 2-methoxyestradiol and Hypoxia
| Article | Year |
|---|---|
Intramuscular injection of sotagliflozin promotes neovascularization in diabetic mice through enhancing skeletal muscle cells paracrine function.
Topics: 2-Methoxyestradiol; Angiogenesis Inducing Agents; Animals; Becaplermin; Culture Media, Conditioned; Diabetes Mellitus, Experimental; Glucose; Glycosides; Hindlimb; Hypoxia; Injections, Intramuscular; Ischemia; Mice; Muscle, Skeletal; Neovascularization, Pathologic; Neovascularization, Physiologic; Sodium-Glucose Transporter 2 Inhibitors; Vascular Endothelial Growth Factor A | 2022 |
Combined Effects of 2-Methoxyestradiol (Hypoxia-Inducible Factor 1
Topics: 2-Methoxyestradiol; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Dasatinib; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Vascular Endothelial Growth Factor A | 2022 |
Effect and mechanism of pirfenidone combined with 2-methoxy-estradiol perfusion through portal vein on hepatic artery hypoxia-induced hepatic fibrosis.
Topics: 2-Methoxyestradiol; Animals; Collagen; Fibrosis; Hepatic Artery; Hypoxia; Liver Cirrhosis; Matrix Metalloproteinase 2; Perfusion; Portal Vein; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1 | 2023 |
2-Methoxyestradiol Attenuates the Development and Retards the Progression of Hypoxia-And Alpha-Naphthylthiourea-Induced Pulmonary Hypertension.
Topics: 2-Methoxyestradiol; Animals; Hypertension, Pulmonary; Hypoxia; Rats; Rats, Sprague-Dawley; Thiourea | 2021 |
2-Methoxyestradiol attenuates chronic-intermittent-hypoxia-induced pulmonary hypertension through regulating microRNA-223.
Topics: 2-Methoxyestradiol; Animals; Cell Movement; Cell Proliferation; Hypertension, Pulmonary; Hypoxia; MicroRNAs; Rats; Rats, Sprague-Dawley; Sleep Apnea, Obstructive; Up-Regulation | 2019 |
Influence of 2-Methoxyestradiol and Sex on Hypoxia-Induced Pulmonary Hypertension and Hypoxia-Inducible Factor-1-α.
Topics: 2-Methoxyestradiol; Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Cytoskeleton; Disease Models, Animal; Female; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats, Sprague-Dawley; Sex Factors; Signal Transduction; Vascular Remodeling | 2019 |
Autophagy mediates 2-methoxyestradiol-inhibited scleroderma collagen synthesis and endothelial-to-mesenchymal transition induced by hypoxia.
Topics: 2-Methoxyestradiol; Actins; Autophagy; Cells, Cultured; Collagen Type I; Connective Tissue Growth Factor; Epithelial-Mesenchymal Transition; Fibroblasts; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia; Platelet Endothelial Cell Adhesion Molecule-1; Scleroderma, Systemic; Skin; Vimentin | 2019 |
Hypoxia augments NaHS-induced ANP secretion via KATP channel, HIF-1α and PPAR-γ pathway.
Topics: 2-Methoxyestradiol; Anilides; Animals; Atrial Natriuretic Factor; Bosentan; Gene Expression Regulation; Glyburide; Heart Atria; Hydrogen Sulfide; Hypertension, Pulmonary; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; KATP Channels; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Organ Culture Techniques; Oxygen; Pinacidil; Potassium Channel Blockers; PPAR gamma; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfides | 2019 |
Hypoxia-inducible factor-1α upregulation in microglia following hypoxia protects against ischemia-induced cerebral infarction.
Topics: 2-Methoxyestradiol; Animals; Blotting, Western; Brain; Brain Ischemia; Cell Line; Central Nervous System Agents; Cerebral Infarction; Disease Models, Animal; Estradiol; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Mice, Inbred C57BL; Microglia; Random Allocation; Up-Regulation | 2014 |
2-Methoxyestradiol regulates VEGFR-2 and sFlt-1 expression in human placenta.
Topics: 2-Methoxyestradiol; Cells, Cultured; Estradiol; Female; Gene Expression Regulation; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Placenta; Pregnancy; Pregnancy Trimester, First; Primary Cell Culture; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2015 |
2ME2 inhibits the activated hypoxia-inducible pathways by cabozantinib and enhances its efficacy against medullary thyroid carcinoma.
Topics: 2-Methoxyestradiol; Active Transport, Cell Nucleus; Adult; Anilides; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Neuroendocrine; Cell Proliferation; Cell Survival; Estradiol; Female; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Isoenzymes; Ki-67 Antigen; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Pyridines; Signal Transduction; Thyroid Neoplasms; Xenograft Model Antitumor Assays | 2016 |
In vivo dynamics and distinct functions of hypoxia in primary tumor growth and organotropic metastasis of breast cancer.
Topics: 2-Methoxyestradiol; Animals; Biomarkers, Tumor; Bone Neoplasms; Breast Neoplasms; Estradiol; Female; Gene Expression Profiling; Genes, Dominant; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mice; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Prognosis; Survival Rate; Tubulin Modulators; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2010 |
2-Methoxyoestradiol inhibits glucose transport in rodent skeletal muscle.
Topics: 2-Methoxyestradiol; Animals; Deoxyglucose; Estradiol; Glucose; Glucose Transporter Type 4; Hydrogen Peroxide; Hypoxia; Insulin; Male; Mice; Muscle Contraction; Muscle, Skeletal; Rats | 2010 |
Anti-angiogenic therapy and chemotherapy affect 99mTc sestamibi and 99mTc-HL91 accumulation differently in tumour xenografts.
Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Estradiol; Fluorouracil; Humans; Hypoxia; Kinetics; Mice; Neoplasm Transplantation; Neovascularization, Pathologic; Organotechnetium Compounds; Oximes; Oxygen; Radiopharmaceuticals; Technetium Tc 99m Sestamibi; Time Factors | 2005 |
Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia.
Topics: 2-Methoxyestradiol; Albumins; Animals; Blood Pressure; Catechol O-Methyltransferase; Creatinine; Disease Models, Animal; Estradiol; Female; Humans; Hypertension; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Killer Cells, Natural; Litter Size; Male; Mice; Placenta; Pre-Eclampsia; Pregnancy; Proteinuria; Vascular Endothelial Growth Factor Receptor-1 | 2008 |