Page last updated: 2024-08-24

2-methoxyestradiol and Glioma

2-methoxyestradiol has been researched along with Glioma in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Brassesco, MS; Candido, MF; Medeiros, M; Valera, ET1
Escuin-Borras, D; Giannakakou, P; Goodman, MM; Mun, J; Voll, RJ; Wang, Y1
Kirches, E; Warich-Kirches, M1
Chisu, V; Manca, P1
Braeuninger, S; Chamaon, K; Dietzmann, K; Kanakis, D; Kirches, E; Krause, G; Mawrin, C; Stojek, J1
Brat, DJ; Cho, HT; Devi, S; Escuin, D; Giannakakou, P; Kang, SH; Lavallee, TM; Liang, Z; Mao, H; Olson, JJ; Shim, H; Simons, JW; Van Meir, EG; Zhang, Z1
Lv, G; Wang, H; Wang, L; Yu, H; Zhang, J; Zhang, X; Zhao, S; Zou, H1

Reviews

2 review(s) available for 2-methoxyestradiol and Glioma

ArticleYear
The multifaceted NF-kB: are there still prospects of its inhibition for clinical intervention in pediatric central nervous system tumors?
    Cellular and molecular life sciences : CMLS, 2021, Volume: 78, Issue:17-18

    Topics: 2-Methoxyestradiol; Antineoplastic Agents; Central Nervous System Neoplasms; Child; Glioma; Hedgehog Proteins; Humans; Medulloblastoma; NF-kappa B; Wnt Proteins

2021
2-methoxyestradiol as a potential cytostatic drug in gliomas?
    Anti-cancer agents in medicinal chemistry, 2009, Volume: 9, Issue:1

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Autophagy; Estradiol; Glioma; Humans; Treatment Outcome; Tubulin Modulators

2009

Other Studies

5 other study(ies) available for 2-methoxyestradiol and Glioma

ArticleYear
Syntheses and biological activities of novel 2-methoxyestradiol analogs, 2-fluoroethoxyestradiol and 2-fluoropropanoxyestradiol, and a radiosynthesis of 2-[(18)F]fluoroethoxyestradiol for positron emission tomography.
    Nuclear medicine and biology, 2008, Volume: 35, Issue:5

    Topics: 2-Methoxyestradiol; Cell Line, Tumor; Down-Regulation; Estradiol; Female; Fluorine Radioisotopes; Glioma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indicators and Reagents; Isotope Labeling; Magnetic Resonance Spectroscopy; Microtubules; Ovarian Neoplasms; Positron-Emission Tomography; Quality Control; Radiopharmaceuticals; Tissue Distribution

2008
2-methoxyestradiol induces morpho-functional changes and impairs the microtubular system in mouse neuroblastoma and rat glioma cells.
    Archives italiennes de biologie, 2010, Volume: 148, Issue:1

    Topics: 2-Methoxyestradiol; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Estradiol; Gene Expression Regulation, Neoplastic; Glioma; Mice; Microtubules; Neuroblastoma; Rats; Tubulin; Tubulin Modulators

2010
Micromolar concentrations of 2-methoxyestradiol kill glioma cells by an apoptotic mechanism, without destroying their microtubule cytoskeleton.
    Journal of neuro-oncology, 2005, Volume: 72, Issue:1

    Topics: 2-Methoxyestradiol; Analysis of Variance; Animals; Antineoplastic Agents, Hormonal; Apoptosis; Brain Neoplasms; Caspase 3; Caspases; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; Cytoskeleton; Dose-Response Relationship, Drug; Estradiol; Estradiol Congeners; Glioma; Humans; Microtubules; Rats

2005
Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model.
    Cancer research, 2006, Dec-15, Volume: 66, Issue:24

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line, Tumor; Disease Models, Animal; Estradiol; Glioma; Magnetic Resonance Imaging; Rats; Rats, Inbred F344; Tubulin Modulators

2006
Enhanced radiation-induced cytotoxic effect by 2-ME in glioma cells is mediated by induction of cell cycle arrest and DNA damage via activation of ATM pathways.
    Brain research, 2007, Dec-14, Volume: 1185

    Topics: 2-Methoxyestradiol; Analysis of Variance; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Checkpoint Kinase 2; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Radiation; Estradiol; Gene Expression Regulation, Neoplastic; Glioma; Histones; Humans; Indoles; Protein Serine-Threonine Kinases; Radiotherapy; RNA, Small Interfering; Signal Transduction; Transfection; Tumor Suppressor Proteins

2007