Compounds > 2-methoxyestradiol
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2-methoxyestradiol and Edema-Proteinuria-Hypertension Gestosis

2-methoxyestradiol has been researched along with Edema-Proteinuria-Hypertension Gestosis in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (21.43)29.6817
2010's10 (71.43)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Dong, T; Fukunaga, K; Imachi, H; Iwama, H; Kobayashi, T; Lyu, J; Murao, K; Saheki, T; Sato, S; Zhang, G1
Chen, M; Chen, Q; Hu, Z; Wan, J; Yin, Y; Zeng, K; Zhao, M1
España-Perrot, PP; Illanes, SE; Norwitz, ER; Perez-Sepulveda, A1
Bonacasa, B; Bosch, V; Delgado, JL; Fenoy, FJ; Hernández, I; Hernández, M; Mendiola, J; Pertegal, M; Salom, MG1
Chang, X; Chen, X; Duan, T; Shen, Z; Wang, K; Wu, Y; Ying, H; Zheng, J; Zhou, J; Zhou, Q1
Bonacasa, B; Bosch, V; Corno, A; Delgado, JL; Fenoy, FJ; Hernández, I; Hernández, M; López, B; Mendiola, J; Pertegal, M1
Dragun, D; Haase-Fielitz, A1
Banerjee, S; Chambers, AE; Randeva, H1
Kalluri, R; Kanasaki, K; Lee, SB; McElrath, TF; Shenoy, VK; Whitesides, GM; Wong, AP; Xu, Y1
Kalluri, R; Kanasaki, K; Shenoy, V1
Gkagtzis, DC; Hadjichristodoulou, CS; Koukoulis, GN; Tsakalof, AK1
Figueroa-Diesel, H; Galaz, J; Illanes, SE; Larraín, R; Michea, L; Nien, JK; Pérez-Sepúlveda, A; Serra, R; Torres, MJ; Valenzuela, FJ1
Cho, GJ; Kim, HJ; Oh, MJ; Seol, HJ1
Ahmad, S; Augustin, HG; Folkman, J; Gattone, VH; Hamano, Y; Kalluri, R; Kanasaki, K; Palmsten, K; Parry, S; Strauss, JF; Sugimoto, H; Xie, L1

Reviews

3 review(s) available for 2-methoxyestradiol and Edema-Proteinuria-Hypertension Gestosis

ArticleYear
Metabolic pathways involved in 2-methoxyestradiol synthesis and their role in preeclampsia.
    Reproductive sciences (Thousand Oaks, Calif.), 2013, Volume: 20, Issue:9

    Topics: 2-Methoxyestradiol; Animals; Aromatase; Biomarkers; Catechol O-Methyltransferase; Estradiol; Female; Humans; Pre-Eclampsia; Pregnancy; Risk Factors; Signal Transduction; Up-Regulation

2013
Low catechol-O-methyltransferase and 2-methoxyestradiol in preeclampsia: more than a unifying hypothesis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:1

    Topics: 2-Methoxyestradiol; Animals; Catechol O-Methyltransferase; Endothelium, Vascular; Estradiol; Female; Humans; Mice; Models, Biological; Neovascularization, Pathologic; Pre-Eclampsia; Pregnancy; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1

2009
Pre-eclampsia: connecting angiogenic and metabolic pathways.
    Trends in endocrinology and metabolism: TEM, 2010, Volume: 21, Issue:9

    Topics: 2-Methoxyestradiol; Catechol O-Methyltransferase; Estradiol; Female; Humans; Neovascularization, Pathologic; Pre-Eclampsia; Pregnancy

2010

Other Studies

11 other study(ies) available for 2-methoxyestradiol and Edema-Proteinuria-Hypertension Gestosis

ArticleYear
Treatment with 2-methoxyestradiol increases endothelial nitric oxide synthase activity via scavenger receptor class BI in human umbilical vein endothelial cells.
    Molecular human reproduction, 2020, 06-01, Volume: 26, Issue:6

    Topics: 2-Methoxyestradiol; Blotting, Western; Chromatin Immunoprecipitation; Female; Human Umbilical Vein Endothelial Cells; Humans; Lipoproteins, HDL; Nitric Oxide; Nitric Oxide Synthase Type III; Pre-Eclampsia; Pregnancy

2020
The reduction in circulating levels of estrogen and progesterone in women with preeclampsia.
    Pregnancy hypertension, 2018, Volume: 11

    Topics: 2-Methoxyestradiol; Adult; Biomarkers; Case-Control Studies; Culture Media, Conditioned; Down-Regulation; Estradiol; Female; Fetal Growth Retardation; Humans; Hydrogen Peroxide; Placenta; Pre-Eclampsia; Pregnancy; Progesterone; Receptors, Estrogen; Receptors, Progesterone; Severity of Illness Index; Tissue Culture Techniques; Tyrosine; Young Adult

2018
2-methoxyestradiol plasma levels are associated with clinical severity indices and biomarkers of preeclampsia.
    Reproductive sciences (Thousand Oaks, Calif.), 2015, Volume: 22, Issue:2

    Topics: 2-Methoxyestradiol; Adult; Biomarkers; Case-Control Studies; Down-Regulation; Estradiol; Female; Humans; Placenta Growth Factor; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Proteins; Pregnancy Trimester, Third; Prognosis; Prospective Studies; Severity of Illness Index; Vascular Endothelial Growth Factor Receptor-1

2015
Decreased maternal serum 2-methoxyestradiol levels are associated with the development of preeclampsia.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2014, Volume: 34, Issue:6

    Topics: 2-Methoxyestradiol; Adult; Catechol O-Methyltransferase; Cell Hypoxia; Cell Movement; Cell Proliferation; Estradiol; Female; Humans; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First

2014
Fetal Val108/158Met catechol-O-methyltransferase (COMT) polymorphism and placental COMT activity are associated with the development of preeclampsia.
    Fertility and sterility, 2016, Volume: 105, Issue:1

    Topics: 2-Methoxyestradiol; Adult; Biomarkers; Blood Pressure; Case-Control Studies; Catechol O-Methyltransferase; Chi-Square Distribution; Estradiol; Female; Fetal Blood; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Haplotypes; Homocysteine; Hospitals, University; Humans; Logistic Models; Methylenetetrahydrofolate Reductase (NADPH2); Multivariate Analysis; Odds Ratio; Phenotype; Placenta; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Prospective Studies; Risk Assessment; Risk Factors; Spain

2016
Mouse models for preeclampsia: disruption of redox-regulated signaling.
    Reproductive biology and endocrinology : RB&E, 2009, Jan-15, Volume: 7

    Topics: 2-Methoxyestradiol; Animals; Catechol O-Methyltransferase; Disease Models, Animal; Estradiol; Female; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mitochondrial Proteins; Oxidation-Reduction; Oxidative Stress; Pre-Eclampsia; Pregnancy; Signal Transduction; Superoxide Dismutase

2009
Preeclampsia: 2-methoxyestradiol induces cytotrophoblast invasion and vascular development specifically under hypoxic conditions.
    The American journal of pathology, 2010, Volume: 176, Issue:2

    Topics: 2-Methoxyestradiol; Animals; Blood Vessels; Catechol O-Methyltransferase; Cell Adhesion; Cell Hypoxia; Cell Movement; Cells, Cultured; Drug Synergism; Estradiol; Female; Humans; Mice; Mice, Knockout; Neovascularization, Physiologic; Oxygen; Pre-Eclampsia; Pregnancy; Trophoblasts

2010
Development of GC-MS/MS method with programmable temperature vaporization large volume injection for monitoring of 17β-estradiol and 2-methoxyestradiol in plasma.
    Analytica chimica acta, 2012, Jan-04, Volume: 709

    Topics: 2-Methoxyestradiol; Estradiol; Female; Gas Chromatography-Mass Spectrometry; Humans; Pre-Eclampsia; Pregnancy; Solid Phase Extraction; Temperature; Volatilization

2012
Low 2-methoxyestradiol levels at the first trimester of pregnancy are associated with the development of pre-eclampsia.
    Prenatal diagnosis, 2012, Volume: 32, Issue:11

    Topics: 2-Methoxyestradiol; Adult; Case-Control Studies; Catechol O-Methyltransferase; Estradiol; Female; Genetic Predisposition to Disease; Humans; Polymorphism, Single Nucleotide; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Tubulin Modulators

2012
2-methoxyoestradiol levels and placental catechol-O-methyltransferase expression in patients with late-onset preeclampsia.
    Archives of gynecology and obstetrics, 2013, Volume: 287, Issue:5

    Topics: 2-Methoxyestradiol; Adult; Birth Weight; Blotting, Western; Catechol O-Methyltransferase; Enzyme-Linked Immunosorbent Assay; Estradiol; Female; Gestational Age; Humans; Infant, Newborn; Placenta; Pre-Eclampsia; Pregnancy; Republic of Korea

2013
Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia.
    Nature, 2008, Jun-19, Volume: 453, Issue:7198

    Topics: 2-Methoxyestradiol; Albumins; Animals; Blood Pressure; Catechol O-Methyltransferase; Creatinine; Disease Models, Animal; Estradiol; Female; Humans; Hypertension; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Killer Cells, Natural; Litter Size; Male; Mice; Placenta; Pre-Eclampsia; Pregnancy; Proteinuria; Vascular Endothelial Growth Factor Receptor-1

2008