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2-methoxyestradiol and Cancer of Pancreas

2-methoxyestradiol has been researched along with Cancer of Pancreas in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's7 (63.64)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Basu, A; Haldar, S1
Baumunk, D; Fotopoulou, C; Schmidt, SC; Schumacher, G1
Du, Y; Zhou, J1
Gebhard, MM; Klar, E; Ryschich, E; Schmidt, J; Werner, J1
Kataoka, M; Mukhopadhyay, T; Roth, JA; Schumacher, G2
Basu, A; Bhalla, K; Bouziane, M; Castle, VP; Haldar, S1
Bahra, M; Cramer, T; Hoffmann, J; Jacob, D; Lage, H; Pfitzmann, R; Pratschke, J; Schmidt, S; Schumacher, G; Spinelli, A1
Farrar, WL; Hurt, EM; Peng, B; Thomas, SB1
Diamantidis, M; Kountouras, J; Tsapournas, G; Zavos, C1
Basu, A; Das, M; Haldar, S; Qanungo, S1

Reviews

1 review(s) available for 2-methoxyestradiol and Cancer of Pancreas

ArticleYear
New aspects of regulatory signaling pathways and novel therapies in pancreatic cancer.
    Current molecular medicine, 2008, Volume: 8, Issue:1

    Topics: 2-Methoxyestradiol; Apoptosis; Apoptosis Regulatory Proteins; Caveolin 1; Cyclins; Cyclooxygenase 1; Cyclooxygenase 2; Estradiol; Fas Ligand Protein; fas Receptor; Granzymes; Humans; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Mitochondrial Proteins; Mitogen-Activated Protein Kinases; Mucins; Neuropeptides; Pancreatic Neoplasms; Perforin; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptors, Notch; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2008

Other Studies

10 other study(ies) available for 2-methoxyestradiol and Cancer of Pancreas

ArticleYear
2-Methoxyestradiol mediated signaling network in pancreatic cancer.
    Frontiers in bioscience (Landmark edition), 2009, 01-01, Volume: 14, Issue:6

    Topics: 2-Methoxyestradiol; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Estradiol; Humans; Hypoxia-Inducible Factor 1; NF-kappa B; Pancreatic Neoplasms; Receptors, Glucocorticoid; Signal Transduction; Vascular Endothelial Growth Factor A

2009
Additive growth inhibition after combined treatment of 2-methoxyestradiol and conventional chemotherapeutic agents in human pancreatic cancer cells.
    Anticancer research, 2010, Volume: 30, Issue:11

    Topics: 2-Methoxyestradiol; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cetuximab; Cisplatin; Deoxycytidine; Drug Synergism; Estradiol; Female; Flow Cytometry; Fluorescent Antibody Technique; Fluorouracil; Gemcitabine; Humans; Mice; Mice, Nude; Paclitaxel; Pancreatic Neoplasms; Tubulin Modulators

2010
Acquisition of resistance of pancreatic cancer cells to 2-methoxyestradiol is associated with the upregulation of manganese superoxide dismutase.
    Molecular cancer research : MCR, 2012, Volume: 10, Issue:6

    Topics: 2-Methoxyestradiol; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Estradiol; Gamma Rays; Humans; Hydrogen Peroxide; Mitochondria; Pancreatic Neoplasms; Proteomics; Reactive Oxygen Species; RNA Interference; Superoxide Dismutase; Superoxides; Up-Regulation

2012
Angiogenesis inhibition with TNP-470, 2-methoxyestradiol, and paclitaxel in experimental pancreatic carcinoma.
    Pancreas, 2003, Volume: 26, Issue:2

    Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Animals; Apoptosis; Cyclohexanes; Estradiol; Male; Neoplasm Transplantation; O-(Chloroacetylcarbamoyl)fumagillol; Paclitaxel; Pancreatic Neoplasms; Rats; Rats, Inbred Lew; Sesquiterpenes; Time Factors; Tumor Cells, Cultured

2003
[2-methoxyestradiol induces p53 independent apoptosis in pancratic carcinoma and inhibits growth of lung metastasis].
    Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress, 1998, Volume: 115, Issue:Suppl I

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents, Hormonal; Apoptosis; Cell Division; Estradiol; Humans; In Situ Nick-End Labeling; Lung; Lung Neoplasms; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Pancreatic Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1998
Crosstalk between extrinsic and intrinsic cell death pathways in pancreatic cancer: synergistic action of estrogen metabolite and ligands of death receptor family.
    Cancer research, 2006, Apr-15, Volume: 66, Issue:8

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Caspase 8; Caspase 9; Caspases; Cell Line, Tumor; Drug Synergism; Estradiol; fas Receptor; Humans; Membrane Glycoproteins; Mice; Mice, Nude; Pancreatic Neoplasms; Proto-Oncogene Proteins c-jun; Receptor Cross-Talk; Receptors, Tumor Necrosis Factor; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Up-Regulation; Xenograft Model Antitumor Assays

2006
Antineoplastic activity of 2-methoxyestradiol in human pancreatic and gastric cancer cells with different multidrug-resistant phenotypes.
    Journal of gastroenterology and hepatology, 2007, Volume: 22, Issue:9

    Topics: 2-Methoxyestradiol; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cell Line, Tumor; Drug Resistance, Multiple; Estradiol; Humans; Pancreatic Neoplasms; Phenotype; Stomach Neoplasms

2007
Molecular consequences of SOD2 expression in epigenetically silenced pancreatic carcinoma cell lines.
    British journal of cancer, 2007, Oct-22, Volume: 97, Issue:8

    Topics: 2-Methoxyestradiol; Animals; Carcinoma; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Estradiol; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Mice; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Pancreatic Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase; Tubulin Modulators; Vascular Endothelial Growth Factor Receptor-2

2007
Potent antitumor activity of 2-methoxyestradiol in human pancreatic cancer cell lines.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:3

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Apoptosis; Cell Division; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Estradiol; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Pancreatic Neoplasms; Tumor Cells, Cultured

1999
2-Methoxyestradiol induces mitochondria dependent apoptotic signaling in pancreatic cancer cells.
    Oncogene, 2002, Jun-13, Volume: 21, Issue:26

    Topics: 2-Methoxyestradiol; Apoptosis; bcl-X Protein; Cell Cycle; Estradiol; Humans; Mitochondria; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tumor Cells, Cultured

2002