2-methoxyestradiol has been researched along with Cancer of Ovary in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (50.00) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Kulbacka, J; Piwowar, A; Saczko, J; Sawicka, E; Szydełko, M; Szymańska, B | 1 |
| Kulbacka, J; Piwowar, A; Roik, J; Saczko, J; Sawicka, E | 1 |
| Hales, DB; Hales, K; Pal, P; Petrik, J | 1 |
| Dai, CF; Jobe, SO; Li, HH; Li, XF; Li, Y; Magness, RR; Patankar, MS; Yang, XS; Zhao, YJ; Zheng, J | 1 |
| Bar, J; Bednarz-Misa, I; Choromańska, A; Dubińska-Magiera, M; Kulbacka, J; Marcinkowska, A; Rembiałkowska, N; Saczko, J | 1 |
| Ding, L; Liu, PS; Mu, ZL; Wang, XQ; Zhang, J; Zhou, XX | 1 |
| Dikshit, A; Gao, C; Hales, DB; Hales, K; Small, C | 1 |
| Dikshit, A; Hales, DB; Hales, K | 1 |
| Escuin-Borras, D; Giannakakou, P; Goodman, MM; Mun, J; Voll, RJ; Wang, Y | 1 |
| Brañes, J; Carvajal, J; Cuello, MA; Delpiano, AM; Kato, S; Lange, S; Lipkowitz, S; Owen, GI; Sadarangani, A; Vargas, M | 1 |
| Breen, T; Matei, D; Perkins, S; Quon, C; Schilder, J; Sidor, C; Sutton, G | 1 |
| Comninos, A; Day, JM; Leese, MP; Newman, SP; Potter, BV; Purohit, A; Reed, MJ; Solomon, C | 1 |
| Albitar, M; Hileman, EO; Huang, P; Keating, MJ; Liu, J | 1 |
| Huober, J; Mueck, AO; Seeger, H; Wallwiener, D | 1 |
| Bu, SZ; Guo, ZY; Hou, Y; Huang, Q; Jiang, YM; Min, HB; Ni, X; Wang, JW; Wei, JF; Zheng, SS | 1 |
| Dahut, WL; Figg, WD; Lakhani, NJ; Sparreboom, A; Veenstra, TD; Venitz, J; Xu, X | 1 |
2 trial(s) available for 2-methoxyestradiol and Cancer of Ovary
| Article | Year |
|---|---|
Activity of 2 methoxyestradiol (Panzem NCD) in advanced, platinum-resistant ovarian cancer and primary peritoneal carcinomatosis: a Hoosier Oncology Group trial.
Topics: 2-Methoxyestradiol; Adult; Aged; Antineoplastic Agents; CA-125 Antigen; Disease-Free Survival; Drug Resistance, Neoplasm; Estradiol; Female; Humans; Hydroxyestrones; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Ovarian Neoplasms; Peritoneal Neoplasms | 2009 |
Characterization of in vitro and in vivo metabolic pathways of the investigational anticancer agent, 2-methoxyestradiol.
Topics: 2-Methoxyestradiol; Administration, Oral; Antineoplastic Agents; Biotransformation; Chromatography, High Pressure Liquid; Drugs, Investigational; Estradiol; Female; Glucuronic Acid; Humans; In Vitro Techniques; Male; Microsomes, Liver; Molecular Structure; Ovarian Neoplasms; Oxidation-Reduction; Prostatic Neoplasms; Tandem Mass Spectrometry | 2007 |
14 other study(ies) available for 2-methoxyestradiol and Cancer of Ovary
| Article | Year |
|---|---|
The Influence of Interaction between Cadmium with 17β-Estradiol, 2-Methoxyestradiol and 16α-Hydroxyestrone on Viability and p-Glycoprotein in Ovarian Cancer Cell Line.
Topics: 2-Methoxyestradiol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cadmium; Carcinoma, Ovarian Epithelial; Cell Line; Estradiol; Estrogens; Humans; Ovarian Neoplasms | 2022 |
Effect of Interaction between 17β-Estradiol, 2-Methoxyestradiol and 16α-Hydroxyestrone with Chromium (VI) on Ovary Cancer Line SKOV-3: Preliminary Study.
Topics: 2-Methoxyestradiol; Apoptosis; Cell Line, Tumor; Cell Survival; Chromates; Chromium; Drug Antagonism; Drug Synergism; Estradiol; Female; Humans; Hydroxyestrones; Ovarian Neoplasms; Potassium Compounds | 2020 |
Pro-apoptotic and anti-angiogenic actions of 2-methoxyestradiol and docosahexaenoic acid, the biologically derived active compounds from flaxseed diet, in preventing ovarian cancer.
Topics: 2-Methoxyestradiol; Animals; Apoptosis; Cell Line, Tumor; Chickens; Chorioallantoic Membrane; Dietary Supplements; Disease Models, Animal; Docosahexaenoic Acids; Female; Flax; Humans; MAP Kinase Signaling System; Neovascularization, Pathologic; Ovarian Neoplasms; Ovary; Seeds | 2019 |
Estradiol 17β and its metabolites stimulate cell proliferation and antagonize ascorbic acid-suppressed cell proliferation in human ovarian cancer cells.
Topics: 2-Methoxyestradiol; Aryl Hydrocarbon Hydroxylases; Ascorbic Acid; Catechol O-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens, Catechol; Female; Humans; Ovarian Neoplasms; Time Factors | 2014 |
Oxidative modification induced by photodynamic therapy with Photofrin®II and 2-methoxyestradiol in human ovarian clear carcinoma (OvBH-1) and human breast adenocarcinoma (MCF-7) cells.
Topics: 2-Methoxyestradiol; Adenocarcinoma; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cytoskeleton; Dihematoporphyrin Ether; Estradiol; Female; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Immunohistochemistry; Nitric Oxide Synthase Type II; Ovarian Neoplasms; Oxidation-Reduction; Photochemotherapy | 2015 |
Underlying mechanism of 2-methoxyestradiol-induced apoptosis and growth arrest in SKOV3 human ovarian cancer cells.
Topics: 2-Methoxyestradiol; Apoptosis; Apoptosis Regulatory Proteins; Base Sequence; bcl-2-Associated X Protein; Carboplatin; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Estradiol; Female; Humans; Ovarian Neoplasms; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger | 2015 |
Flaxseed and its components differentially affect estrogen targets in pre-neoplastic hen ovaries.
Topics: 2-Methoxyestradiol; Animals; Avian Proteins; Chickens; Cytochrome P-450 CYP1A1; Dietary Supplements; Estradiol; Female; Flax; Gene Expression; Linseed Oil; Liver; NF-kappa B; Ovarian Neoplasms; Ovary; Precancerous Conditions; Proto-Oncogene Proteins c-akt; Receptors, Estrogen; Signal Transduction | 2016 |
Whole flaxseed diet alters estrogen metabolism to promote 2-methoxtestradiol-induced apoptosis in hen ovarian cancer.
Topics: 2-Methoxyestradiol; Animals; Apoptosis; Caspase 3; Cell Line, Tumor; Chickens; Cytochrome P-450 CYP1B1; Cytochrome P-450 CYP3A; Dietary Supplements; Estradiol; Estrogen Receptor alpha; Female; Flax; Humans; Ovarian Neoplasms; Ovary; p38 Mitogen-Activated Protein Kinases; Smad7 Protein | 2017 |
Syntheses and biological activities of novel 2-methoxyestradiol analogs, 2-fluoroethoxyestradiol and 2-fluoropropanoxyestradiol, and a radiosynthesis of 2-[(18)F]fluoroethoxyestradiol for positron emission tomography.
Topics: 2-Methoxyestradiol; Cell Line, Tumor; Down-Regulation; Estradiol; Female; Fluorine Radioisotopes; Glioma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indicators and Reagents; Isotope Labeling; Magnetic Resonance Spectroscopy; Microtubules; Ovarian Neoplasms; Positron-Emission Tomography; Quality Control; Radiopharmaceuticals; Tissue Distribution | 2008 |
2-methoxyestradiol mediates apoptosis through caspase-dependent and independent mechanisms in ovarian cancer cells but not in normal counterparts.
Topics: 2-Methoxyestradiol; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspases; Cell Line, Tumor; Drug Synergism; Estradiol; Female; Humans; Ovarian Neoplasms; TNF-Related Apoptosis-Inducing Ligand | 2008 |
The effects of 2-substituted oestrogen sulphamates on the growth of prostate and ovarian cancer cells.
Topics: 2-Methoxyestradiol; Apoptosis; Cell Division; Cell Separation; Estradiol; Estrone; Female; Flow Cytometry; G1 Phase; G2 Phase; Humans; Hydroxyestrones; Immunoblotting; Inhibitory Concentration 50; Male; Mitosis; Models, Chemical; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Time Factors; Tumor Cells, Cultured | 2003 |
Intrinsic oxidative stress in cancer cells: a biochemical basis for therapeutic selectivity.
Topics: 2-Methoxyestradiol; Antineoplastic Agents; Apoptosis; Catalase; Cell Line, Tumor; Estradiol; Female; HL-60 Cells; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Ovarian Neoplasms; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Superoxides | 2004 |
Is the combination with 2-methoxyestradiol able to reduce the dosages of chemotherapeutices in the treatment of human ovarian cancer? Preliminary in vitro investigations.
Topics: 2-Methoxyestradiol; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cell Line, Tumor; Cell Proliferation; Cyclophosphamide; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Epirubicin; Estradiol; Female; Fluorouracil; Humans; Ovarian Neoplasms; Paclitaxel; Taxoids; Vinblastine; Vinorelbine | 2004 |
p38 Mitogen-activated protein kinases is required for counteraction of 2-methoxyestradiol to estradiol-stimulated cell proliferation and induction of apoptosis in ovarian carcinoma cells via phosphorylation Bcl-2.
Topics: 2-Methoxyestradiol; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; DNA Fragmentation; Epithelial Cells; Estradiol; Female; Humans; Ovarian Neoplasms; Ovary; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Point Mutation; Proto-Oncogene Proteins c-bcl-2; Tubulin Modulators | 2006 |