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2-methoxyestradiol and Cancer of Lung

2-methoxyestradiol has been researched along with Cancer of Lung in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (43.75)18.2507
2000's3 (18.75)29.6817
2010's3 (18.75)24.3611
2020's3 (18.75)2.80

Authors

AuthorsStudies
He, C; Mi, Y; Zhang, Y1
Ambele, MA; Durandt, C; Joubert, AM; Pepper, MS; Peta, KT; van Heerden, MB1
Cho, J; Choi, SH; Han, SC; Kim, AR; Kim, J; Kim, JH; Lee, HJ; Lee, YJ; Nam, JK; Park, S1
Aquino-Gálvez, A; Cabello-Gutiérrez, C; Castillejos-López, M; Checa, M; Cisneros, J; Delgado-Tello, J; González-Ávila, G; Gutiérrez-González, LH; Hernández-Jiménez, C; Maldonado-Martínez, HA; Mendoza-Milla, C; Sommer, B; Torres-Espíndola, LM; Trinidad-López, A; Zúñiga, J1
Florczak, U; Kehlbach, R; Peter Rodemann, H; Toulany, M1
Mukhopadhyay, T; Rath, PC1
Hu, G; Kang, Y; Lu, X; Wei, Y; Yan, CH; Yuan, M1
Hsieh, DP; Li, LA; Lin, CJ; Lin, S1
Kataoka, M; Mukhopadhyay, T; Roth, JA; Schumacher, G2
Maxwell, SA; Mukhopadhyay, T; Roth, JA1
Mukhopadhyay, T; Roth, JA2
Green, SJ; Pribluda, VS1
Atkinson, EN; Cristiano, RJ; Kataoka, M; Mukhopadhyay, T; Roth, JA; Schumacher, G1
Huober, JB; Meyn, R; Mukhopadhyay, T; Nakamura, S; Roth, JA1

Other Studies

16 other study(ies) available for 2-methoxyestradiol and Cancer of Lung

ArticleYear
2-methoxyestradiol restrains non-small cell lung cancer tumorigenesis through regulating circ_0010235/miR-34a-5p/NFAT5 axis.
    Thoracic cancer, 2023, Volume: 14, Issue:22

    Topics: 2-Methoxyestradiol; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cell Transformation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; Transcription Factors

2023
Effect of 2-methoxyestradiol treatment on early- and late-stage breast cancer progression in a mouse model.
    Cell biochemistry and function, 2023, Volume: 41, Issue:7

    Topics: 2-Methoxyestradiol; Animals; Lung Neoplasms; Mammary Neoplasms, Animal; Mercaptoethanol; Mice; Mice, Transgenic; Necrosis

2023
Pharmacologic Inhibition of HIF-1α Attenuates Radiation-Induced Pulmonary Fibrosis in a Preclinical Image Guided Radiation Therapy.
    International journal of radiation oncology, biology, physics, 2021, 02-01, Volume: 109, Issue:2

    Topics: 2-Methoxyestradiol; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mice; Pulmonary Fibrosis; Radiation Injuries; Radiotherapy, Image-Guided

2021
Effects of 2-methoxyestradiol on apoptosis and HIF-1α and HIF-2α expression in lung cancer cells under normoxia and hypoxia.
    Oncology reports, 2016, Volume: 35, Issue:1

    Topics: 2-Methoxyestradiol; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Cell Hypoxia; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Estradiol; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms

2016
2-Methoxyestradiol-induced radiosensitization is independent of SOD but depends on inhibition of Akt and DNA-PKcs activities.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2009, Volume: 92, Issue:3

    Topics: 2-Methoxyestradiol; Adenocarcinoma; Apoptosis; Blotting, Western; Cell Line, Tumor; DNA Breaks, Double-Stranded; DNA Damage; DNA-Activated Protein Kinase; Enzyme Activation; Estradiol; Humans; Lung Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Radiation Dosage; Radiation Tolerance; Radiation, Ionizing; Sensitivity and Specificity; Superoxide Dismutase

2009
p53 gene expression and 2-methoxyestradiol treatment differentially induce nuclear factor kappa B activation in human lung cancer cells with different p53 phenotypes.
    DNA and cell biology, 2009, Volume: 28, Issue:12

    Topics: 2-Methoxyestradiol; Adenoviridae; Animals; Base Sequence; Cytoplasm; DNA; Estradiol; Gene Expression Regulation, Neoplastic; Humans; I-kappa B Kinase; Lung Neoplasms; Mice; NF-kappa B; Phenotype; Signal Transduction; Tumor Suppressor Protein p53

2009
In vivo dynamics and distinct functions of hypoxia in primary tumor growth and organotropic metastasis of breast cancer.
    Cancer research, 2010, May-15, Volume: 70, Issue:10

    Topics: 2-Methoxyestradiol; Animals; Biomarkers, Tumor; Bone Neoplasms; Breast Neoplasms; Estradiol; Female; Gene Expression Profiling; Genes, Dominant; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mice; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Prognosis; Survival Rate; Tubulin Modulators; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2010
ERα phenotype, estrogen level, and benzo[a]pyrene exposure modulate tumor growth and metabolism of lung adenocarcinoma cells.
    Lung cancer (Amsterdam, Netherlands), 2012, Volume: 75, Issue:3

    Topics: 2-Methoxyestradiol; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Estradiol; Estrogen Receptor alpha; Estrogens; Estrogens, Catechol; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, Nude; Ovariectomy; Up-Regulation; Xenograft Model Antitumor Assays

2012
[2-methoxyestradiol induces p53 independent apoptosis in pancratic carcinoma and inhibits growth of lung metastasis].
    Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress, 1998, Volume: 115, Issue:Suppl I

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents, Hormonal; Apoptosis; Cell Division; Estradiol; Humans; In Situ Nick-End Labeling; Lung; Lung Neoplasms; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Pancreatic Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1998
Analysis of phosphorylated isoforms of the p53 tumor suppressor protein in human lung carcinoma cells undergoing apoptosis.
    Electrophoresis, 1996, Volume: 17, Issue:11

    Topics: 2-Methoxyestradiol; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; DNA Fragmentation; Electrophoresis, Gel, Two-Dimensional; Estradiol; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasm Proteins; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1996
Induction of apoptosis in human lung cancer cells after wild-type p53 activation by methoxyestradiol.
    Oncogene, 1997, Jan-23, Volume: 14, Issue:3

    Topics: 2-Methoxyestradiol; Apoptosis; Blotting, Northern; Estradiol; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Lung Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1997
A good estrogen.
    Science (New York, N.Y.), 1998, May-15, Volume: 280, Issue:5366

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Catechol O-Methyltransferase; Estradiol; Humans; Lung Neoplasms; Melanoma; Neovascularization, Pathologic

1998
Superinduction of wild-type p53 protein after 2-methoxyestradiol treatment of Ad5p53-transduced cells induces tumor cell apoptosis.
    Oncogene, 1998, Jul-16, Volume: 17, Issue:2

    Topics: 2-Methoxyestradiol; Adenoviridae; Apoptosis; Estradiol; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Genetic Vectors; Humans; Lung Neoplasms; Tumor Suppressor Protein p53

1998
An agent that increases tumor suppressor transgene product coupled with systemic transgene delivery inhibits growth of metastatic lung cancer in vivo.
    Cancer research, 1998, Nov-01, Volume: 58, Issue:21

    Topics: 2-Methoxyestradiol; Adenoviridae; Estradiol; Genes, p53; Genetic Therapy; Genetic Vectors; Humans; Lung Neoplasms; Neovascularization, Pathologic; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1998
Potent antitumor activity of 2-methoxyestradiol in human pancreatic cancer cell lines.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:3

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Apoptosis; Cell Division; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Estradiol; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Pancreatic Neoplasms; Tumor Cells, Cultured

1999
Oral administration of an estrogen metabolite-induced potentiation of radiation antitumor effects in presence of wild-type p53 in non-small-cell lung cancer.
    International journal of radiation oncology, biology, physics, 2000, Nov-01, Volume: 48, Issue:4

    Topics: 2-Methoxyestradiol; Administration, Oral; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Division; Combined Modality Therapy; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Estradiol; Humans; Lung Neoplasms; Neoplasm Proteins; Radiation-Sensitizing Agents; Radiobiology; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tumor Suppressor Protein p53

2000