Page last updated: 2024-08-24

2-methoxyestradiol and Brain Neoplasms

2-methoxyestradiol has been researched along with Brain Neoplasms in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Durden, DL; Joshi, S; Kesari, S; Makale, MT; Muh, CR; Singh, AR1
Garcia, GE; Kumar, AP; Levin, VA; Orsborn, J; Slaga, TJ1
Barone, TA; Ciesielski, MJ; Fenstermaker, RA; Lis, A; Plunkett, RJ; Scott, BE1
Braeuninger, S; Chamaon, K; Dietzmann, K; Kanakis, D; Kirches, E; Krause, G; Mawrin, C; Stojek, J1
Brat, DJ; Cho, HT; Devi, S; Escuin, D; Giannakakou, P; Kang, SH; Lavallee, TM; Liang, Z; Mao, H; Olson, JJ; Shim, H; Simons, JW; Van Meir, EG; Zhang, Z1

Other Studies

5 other study(ies) available for 2-methoxyestradiol and Brain Neoplasms

ArticleYear
PTEN status mediates 2ME2 anti-tumor efficacy in preclinical glioblastoma models: role of HIF1α suppression.
    Journal of neuro-oncology, 2014, Volume: 116, Issue:1

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Chromones; Disease Models, Animal; Enzyme Inhibitors; Estradiol; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Nude; Morpholines; PTEN Phosphohydrolase; Xenograft Model Antitumor Assays

2014
2-Methoxyestradiol interferes with NF kappa B transcriptional activity in primitive neuroectodermal brain tumors: implications for management.
    Carcinogenesis, 2003, Volume: 24, Issue:2

    Topics: 2-Methoxyestradiol; Apoptosis; Brain Neoplasms; Cell Division; Estradiol; Humans; Medulloblastoma; NF-kappa B; Transcription, Genetic; Tumor Cells, Cultured

2003
2-Methoxyestradiol inhibits proliferation of normal and neoplastic glial cells, and induces cell death, in vitro.
    Cancer letters, 2004, Sep-15, Volume: 213, Issue:1

    Topics: 2-Methoxyestradiol; Animals; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Division; Estradiol; Female; Glioblastoma; Humans; Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation

2004
Micromolar concentrations of 2-methoxyestradiol kill glioma cells by an apoptotic mechanism, without destroying their microtubule cytoskeleton.
    Journal of neuro-oncology, 2005, Volume: 72, Issue:1

    Topics: 2-Methoxyestradiol; Analysis of Variance; Animals; Antineoplastic Agents, Hormonal; Apoptosis; Brain Neoplasms; Caspase 3; Caspases; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; Cytoskeleton; Dose-Response Relationship, Drug; Estradiol; Estradiol Congeners; Glioma; Humans; Microtubules; Rats

2005
Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model.
    Cancer research, 2006, Dec-15, Volume: 66, Issue:24

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line, Tumor; Disease Models, Animal; Estradiol; Glioma; Magnetic Resonance Imaging; Rats; Rats, Inbred F344; Tubulin Modulators

2006