2-methoxyestradiol has been researched along with Brain Ischemia in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Huang, T; Huang, W; Peng, Z; Xie, C; Yu, L; Zhang, Z; Zhu, D | 1 |
| Chen, C; Ostrowski, RP; Tang, J; Zhang, JH; Zhou, C | 1 |
| Chang, WC; Gean, PW; Hung, JJ; Ou, LC; Yeh, SH | 1 |
| Chen, SD; Ding, JQ; Ma, JF; Pan, J; Wang, XQ; Xin, XY; Yang, GY | 1 |
| Chen, LB; Li, Y; Xia, ZL | 1 |
| Chen, C; Han, J; Hu, Q; Lei, J; Luan, L; Nanda, A; Qin, L; Shi, X; Wang, K; Yan, J; Yang, L; Zhou, C | 1 |
| Dach, N; Jadhav, V; Matchett, GA; Zhang, JH; Zhou, D | 1 |
7 other study(ies) available for 2-methoxyestradiol and Brain Ischemia
| Article | Year |
|---|---|
Hypoxia-inducible factor-1α upregulation in microglia following hypoxia protects against ischemia-induced cerebral infarction.
Topics: 2-Methoxyestradiol; Animals; Blotting, Western; Brain; Brain Ischemia; Cell Line; Central Nervous System Agents; Cerebral Infarction; Disease Models, Animal; Estradiol; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Mice, Inbred C57BL; Microglia; Random Allocation; Up-Regulation | 2014 |
Suppression of hypoxia-inducible factor-1alpha and its downstream genes reduces acute hyperglycemia-enhanced hemorrhagic transformation in a rat model of cerebral ischemia.
Topics: 2-Methoxyestradiol; Acute Disease; Animals; Brain; Brain Ischemia; Central Nervous System Agents; Disease Models, Animal; Estradiol; Hyperglycemia; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Infarction, Middle Cerebral Artery; Intracranial Hemorrhages; Male; Rats; Rats, Sprague-Dawley; Time Factors | 2010 |
Selective inhibition of early--but not late--expressed HIF-1α is neuroprotective in rats after focal ischemic brain damage.
Topics: 2-Methoxyestradiol; Animals; Antimetabolites; Apoptosis; Brain Ischemia; Cell Survival; Cells, Cultured; Estradiol; Gene Expression Regulation; Gene Silencing; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Stroke; Time Factors | 2011 |
2-methoxyestradiol attenuates autophagy activation after global ischemia.
Topics: 2-Methoxyestradiol; Adenine; Animals; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Hypoxia-Inducible Factor 1; In Situ Nick-End Labeling; Male; Membrane Proteins; Microtubule-Associated Proteins; Mitochondrial Proteins; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Tubulin Modulators; Tumor Suppressor Protein p53; Up-Regulation | 2011 |
HIF-1-α and survivin involved in the anti-apoptotic effect of 2ME2 after global ischemia in rats.
Topics: 2-Methoxyestradiol; Animals; Apoptosis Regulatory Proteins; Brain Ischemia; Down-Regulation; Estradiol; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Microtubule-Associated Proteins; Rats; Rats, Sprague-Dawley; Survivin; Up-Regulation | 2011 |
Multiple effects of 2ME2 and D609 on the cortical expression of HIF-1alpha and apoptotic genes in a middle cerebral artery occlusion-induced focal ischemia rat model.
Topics: 2-Methoxyestradiol; Animals; Apoptosis; Blood-Brain Barrier; Brain Edema; Brain Infarction; Brain Ischemia; Bridged-Ring Compounds; Caspase 3; Cerebral Cortex; Disease Models, Animal; Down-Regulation; Estradiol; Hypoxia-Inducible Factor 1, alpha Subunit; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Membrane Proteins; Mitochondrial Proteins; Neuroprotective Agents; Norbornanes; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiocarbamates; Thiones; Treatment Outcome; Vascular Endothelial Growth Factor A | 2007 |
The effect of 2-methoxyestradiol, a HIF-1 alpha inhibitor, in global cerebral ischemia in rats.
Topics: 2-Methoxyestradiol; Animals; Apoptosis; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Enzyme Inhibitors; Estradiol; Gene Expression Regulation; Hippocampus; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Rats; Rats, Sprague-Dawley; Time Factors | 2008 |