Page last updated: 2024-08-24

2-methoxyestradiol and Brain Injuries

2-methoxyestradiol has been researched along with Brain Injuries in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, G; Chen, J; Gu, C; Hu, Q; Li, J; Mo, H; Wang, L; Wu, C; Yan, F; Zhang, P1
Ding, JY; Kreipke, CW; Rafols, JA; Schafer, P; Schafer, S; Speirs, SL2
Chen, W; Jadhav, V; Tang, J; Zhang, JH1
Ding, JY; Ding, Y; Dornbos, D; Guthikonda, M; Higashida, T; Kreipke, CW; Li, X; Peng, C; Rafols, JA; Rossi, NF; Schafer, P; Schafer, S1
Ali, A; Ding, JY; Ding, Y; Dornbos, D; Geng, X; Guthikonda, M; Konakondla, S; Kreipke, CW; Peng, C; Rafols, JA; Schafer, S; Sikharam, C; Zwagerman, NT1
Ding, JY; Ding, Y; Fredrickson, V; Guthikonda, M; Kassem, H; Kreipke, CW; Peng, C; Rafols, JA; Schafer, S; Shenaq, M1

Other Studies

7 other study(ies) available for 2-methoxyestradiol and Brain Injuries

ArticleYear
Inhibiting HIF-1α by 2ME2 ameliorates early brain injury after experimental subarachnoid hemorrhage in rats.
    Biochemical and biophysical research communications, 2013, Aug-02, Volume: 437, Issue:3

    Topics: 2-Methoxyestradiol; Animals; Brain Injuries; Disease Models, Animal; Endovascular Procedures; Estradiol; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Membrane Proteins; Mitochondrial Proteins; Neuroprotective Agents; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Vascular Endothelial Growth Factor A

2013
Synapse loss regulated by matrix metalloproteinases in traumatic brain injury is associated with hypoxia inducible factor-1alpha expression.
    Brain research, 2009, 05-01, Volume: 1268

    Topics: 2-Methoxyestradiol; Analysis of Variance; Animals; Blotting, Western; Brain; Brain Injuries; Enzyme Inhibitors; Estradiol; Gene Expression; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Minocycline; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Synapses; Synaptophysin

2009
HIF-1 alpha inhibition ameliorates neonatal brain damage after hypoxic-ischemic injury.
    Acta neurochirurgica. Supplement, 2008, Volume: 102

    Topics: 2-Methoxyestradiol; Analysis of Variance; Animals; Animals, Newborn; Brain Edema; Brain Infarction; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Functional Laterality; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Ischemia, Brain; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Vascular Endothelial Growth Factor A

2008
Hypoxia-inducible factor-1alpha signaling in aquaporin upregulation after traumatic brain injury.
    Neuroscience letters, 2009, Mar-27, Volume: 453, Issue:1

    Topics: 2-Methoxyestradiol; Analysis of Variance; Animals; Aquaporin 4; Aquaporins; Blotting, Western; Brain Injuries; Estradiol; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase; Time Factors; Up-Regulation

2009
The role of hypoxia-inducible factor-1α, aquaporin-4, and matrix metalloproteinase-9 in blood-brain barrier disruption and brain edema after traumatic brain injury.
    Journal of neurosurgery, 2011, Volume: 114, Issue:1

    Topics: 2-Methoxyestradiol; Animals; Antibodies, Anti-Idiotypic; Aquaporin 4; Blood-Brain Barrier; Brain Edema; Brain Injuries; Estradiol; Hypoxia-Inducible Factor 1, alpha Subunit; Laminin; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Membrane Proteins; Minocycline; Models, Animal; Occludin; Phosphoproteins; Rats; Rats, Sprague-Dawley; Zonula Occludens-1 Protein

2011
Glycerol accumulation in edema formation following diffuse traumatic brain injury.
    Neurological research, 2012, Volume: 34, Issue:5

    Topics: 2-Methoxyestradiol; Animals; Aquaporins; Brain Edema; Brain Injuries; Disease Models, Animal; Estradiol; Gene Expression Regulation; Glycerol; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Rats; Rats, Sprague-Dawley; Time Factors; Tubulin Modulators

2012
Neuronal damage and functional deficits are ameliorated by inhibition of aquaporin and HIF1α after traumatic brain injury (TBI).
    Journal of the neurological sciences, 2012, Dec-15, Volume: 323, Issue:1-2

    Topics: 2-Methoxyestradiol; Animals; Aquaporin 4; Aquaporins; Brain Damage, Chronic; Brain Edema; Brain Injuries; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cell Membrane Permeability; Corpus Striatum; Estradiol; Fluoresceins; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoglobulin G; Male; Maze Learning; Memory Disorders; Nerve Tissue Proteins; Neurons; Organic Chemicals; Rats; Rats, Sprague-Dawley

2012