2-methoxyestradiol has been researched along with Brain Edema in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, F; Jiang, X; Li, J; Lu, H; Shan, F; Xia, Y; Xiong, A; Xiong, R; Xu, J | 1 |
| Chen, W; Jadhav, V; Tang, J; Zhang, JH | 2 |
| Ding, JY; Ding, Y; Dornbos, D; Guthikonda, M; Higashida, T; Kreipke, CW; Li, X; Peng, C; Rafols, JA; Rossi, NF; Schafer, P; Schafer, S | 1 |
| Ali, A; Ding, JY; Ding, Y; Dornbos, D; Geng, X; Guthikonda, M; Konakondla, S; Kreipke, CW; Peng, C; Rafols, JA; Schafer, S; Sikharam, C; Zwagerman, NT | 1 |
| Chen, G; He, WC; Huo, L; Liu, HX; Ma, C; Meng, CJ; Shen, XM; Shu, Z; Sun, XB; Wang, Z; Zhang, J; Zhu, GQ | 1 |
| Ding, JY; Ding, Y; Fredrickson, V; Guthikonda, M; Kassem, H; Kreipke, CW; Peng, C; Rafols, JA; Schafer, S; Shenaq, M | 1 |
| Chen, C; Han, J; Hu, Q; Lei, J; Luan, L; Nanda, A; Qin, L; Shi, X; Wang, K; Yan, J; Yang, L; Zhou, C | 1 |
8 other study(ies) available for 2-methoxyestradiol and Brain Edema
| Article | Year |
|---|---|
Inhibition of HIF-1α-AQP4 axis ameliorates brain edema and neurological functional deficits in a rat controlled cortical injury (CCI) model.
Topics: 2-Methoxyestradiol; Animals; Antibodies; Aquaporin 4; Blood-Brain Barrier; Brain Edema; Brain Injuries, Traumatic; Cerebral Cortex; Conversion Disorder; Disease Models, Animal; Hippocampus; Hypoxia-Inducible Factor 1, alpha Subunit; Injections, Intravenous; Learning; Male; Memory; Memory Disorders; Neurons; Rats, Sprague-Dawley | 2022 |
HIF-1alpha inhibition ameliorates neonatal brain injury in a rat pup hypoxic-ischemic model.
Topics: 2-Methoxyestradiol; Amino Acids, Dicarboxylic; Animals; Animals, Newborn; Blood-Brain Barrier; Brain; Brain Edema; Brain Infarction; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Female; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Ischemia, Brain; Neuroprotective Agents; Rats; Tubulin Modulators; Vascular Endothelial Growth Factor A | 2008 |
HIF-1 alpha inhibition ameliorates neonatal brain damage after hypoxic-ischemic injury.
Topics: 2-Methoxyestradiol; Analysis of Variance; Animals; Animals, Newborn; Brain Edema; Brain Infarction; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Functional Laterality; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Ischemia, Brain; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Vascular Endothelial Growth Factor A | 2008 |
The role of hypoxia-inducible factor-1α, aquaporin-4, and matrix metalloproteinase-9 in blood-brain barrier disruption and brain edema after traumatic brain injury.
Topics: 2-Methoxyestradiol; Animals; Antibodies, Anti-Idiotypic; Aquaporin 4; Blood-Brain Barrier; Brain Edema; Brain Injuries; Estradiol; Hypoxia-Inducible Factor 1, alpha Subunit; Laminin; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Membrane Proteins; Minocycline; Models, Animal; Occludin; Phosphoproteins; Rats; Rats, Sprague-Dawley; Zonula Occludens-1 Protein | 2011 |
Glycerol accumulation in edema formation following diffuse traumatic brain injury.
Topics: 2-Methoxyestradiol; Animals; Aquaporins; Brain Edema; Brain Injuries; Disease Models, Animal; Estradiol; Gene Expression Regulation; Glycerol; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Rats; Rats, Sprague-Dawley; Time Factors; Tubulin Modulators | 2012 |
Potential contribution of hypoxia-inducible factor-1α, aquaporin-4, and matrix metalloproteinase-9 to blood-brain barrier disruption and brain edema after experimental subarachnoid hemorrhage.
Topics: 2-Methoxyestradiol; Animals; Aquaporin 4; Blood-Brain Barrier; Brain Edema; Disease Models, Animal; Estradiol; Hypoxia-Inducible Factor 1, alpha Subunit; Laminin; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Minocycline; Occludin; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Tubulin Modulators; Zonula Occludens-1 Protein | 2012 |
Neuronal damage and functional deficits are ameliorated by inhibition of aquaporin and HIF1α after traumatic brain injury (TBI).
Topics: 2-Methoxyestradiol; Animals; Aquaporin 4; Aquaporins; Brain Damage, Chronic; Brain Edema; Brain Injuries; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cell Membrane Permeability; Corpus Striatum; Estradiol; Fluoresceins; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoglobulin G; Male; Maze Learning; Memory Disorders; Nerve Tissue Proteins; Neurons; Organic Chemicals; Rats; Rats, Sprague-Dawley | 2012 |
Multiple effects of 2ME2 and D609 on the cortical expression of HIF-1alpha and apoptotic genes in a middle cerebral artery occlusion-induced focal ischemia rat model.
Topics: 2-Methoxyestradiol; Animals; Apoptosis; Blood-Brain Barrier; Brain Edema; Brain Infarction; Brain Ischemia; Bridged-Ring Compounds; Caspase 3; Cerebral Cortex; Disease Models, Animal; Down-Regulation; Estradiol; Hypoxia-Inducible Factor 1, alpha Subunit; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Membrane Proteins; Mitochondrial Proteins; Neuroprotective Agents; Norbornanes; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiocarbamates; Thiones; Treatment Outcome; Vascular Endothelial Growth Factor A | 2007 |