Page last updated: 2024-08-24

2-methoxyestradiol and Bone Cancer

2-methoxyestradiol has been researched along with Bone Cancer in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (40.00)29.6817
2010's7 (46.67)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Cappello, F; Daca, A; Gorska-Ponikowska, M; Kuban-Jankowska, A; Luu, HH; Marino Gammazza, A; Wierzbicka, JM; Wozniak, M; Zmijewski, MA1
Bastian, P; Gorska-Ponikowska, M; Kalinowski, L; Kmiec, Z; Kuban-Jankowska, A; Nussberger, S; Ploska, A; Zauszkiewicz-Pawlak, A; Zubrzycki, A1
Gorska-Ponikowska, M; Gorzynik-Debicka, M; Kostrzewa, T; Kuban-Jankowska, A; Przychodzen, P; Wyszkowska, R1
Cappello, F; Daca, A; Gorska, M; Gorzynik, M; Kuban-Jankowska, A; Lewinska, A; Marino Gammazza, A; Rzeszutek, I; Wnuk, M; Wozniak, M; Zmijewski, M1
Gorska, M; Kuban-Jankowska, A; Wozniak, M; Wyszkowska, RM1
Bravo, D; Maran, A; Sarkar, G; Shogren, KL; Wagner, ER; Yaszemski, MJ; Zuo, D1
Barone, G; Gorska-Ponikowska, M; Kuban-Jankowska, A; Lo Bosco, G; Perricone, U1
Borges, A; Codogno, P; Djavaheri-Mergny, M; Lorin, S; Pierron, G; Ribeiro Dos Santos, L; Ryan, KM; Souquère, S1
Hu, G; Kang, Y; Lu, X; Wei, Y; Yan, CH; Yuan, M1
Goyal, R; Maran, A; Riester, SM; Shogren, KL; Wimbauer, F; Yang, C; Yaszemski, MJ; Zhang, M1
Besançon, F; Djavaheri-Mergny, M; Rouillard, D; Wietzerbin, J1
Tímár, J1
Maran, A; Shogren, KL; Turner, RT; Yaszemski, MJ1
Cicek, M; Clohisy, DR; Goblirsch, MJ; Iwaniec, UT; Oursler, MJ; Ruan, M; Turner, RR; Vrabel, A1
Kennedy, AM; Maran, A; Rickard, DJ; Sibonga, JD; Spelsberg, TC; Turner, RT; Zhang, M1

Other Studies

15 other study(ies) available for 2-methoxyestradiol and Bone Cancer

ArticleYear
The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model.
    International journal of molecular sciences, 2020, Jan-17, Volume: 21, Issue:2

    Topics: 2-Methoxyestradiol; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzoquinones; Bone Neoplasms; Drug Interactions; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Models, Biological; Osteosarcoma

2020
Regulation of mitochondrial dynamics in 2-methoxyestradiol-mediated osteosarcoma cell death.
    Scientific reports, 2021, 01-15, Volume: 11, Issue:1

    Topics: 2-Methoxyestradiol; Apoptosis; Autophagy; bcl-2-Associated X Protein; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Dynamins; Humans; Microscopy, Electron; Mitochondria; Mitochondrial Dynamics; Osteosarcoma; Quinazolinones; Up-Regulation

2021
Anticancer Potential of Oleuropein, the Polyphenol of Olive Oil, With 2-Methoxyestradiol, Separately or in Combination, in Human Osteosarcoma Cells.
    Anticancer research, 2019, Volume: 39, Issue:3

    Topics: 2-Methoxyestradiol; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Synergism; Humans; Iridoid Glucosides; Iridoids; Olive Oil; Osteosarcoma

2019
DNA strand breaks induced by nuclear hijacking of neuronal NOS as an anti-cancer effect of 2-methoxyestradiol.
    Oncotarget, 2015, Jun-20, Volume: 6, Issue:17

    Topics: 2-Methoxyestradiol; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cytokinesis; DNA Breaks; Estradiol; G2 Phase Cell Cycle Checkpoints; Humans; Intracellular Signaling Peptides and Proteins; M Phase Cell Cycle Checkpoints; Nitric Oxide; Nitric Oxide Synthase Type I; Osteosarcoma; Oxidative Stress; Reactive Nitrogen Species; Tumor Suppressor p53-Binding Protein 1

2015
Impact of Apparent Antagonism of Estrogen Receptor β by Fulvestrant on Anticancer Activity of 2-Methoxyestradiol.
    Anticancer research, 2016, Volume: 36, Issue:5

    Topics: 2-Methoxyestradiol; Antineoplastic Agents, Hormonal; Apoptosis; Bone Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Fulvestrant; Gene Expression Regulation, Neoplastic; Histones; Humans; Neoplasm Metastasis; Neoplasm Proteins; Osteosarcoma; Phosphorylation; Protein Processing, Post-Translational

2016
2-Methoxyestradiol-Mediated Induction of Frzb Contributes to Cell Death and Autophagy in MG63 Osteosarcoma Cells.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:6

    Topics: 2-Methoxyestradiol; Antineoplastic Agents; Autophagy; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Estradiol; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Intracellular Signaling Peptides and Proteins; Osteosarcoma; Promoter Regions, Genetic; Wnt Signaling Pathway

2017
2-methoxyestradiol impacts on amino acids-mediated metabolic reprogramming in osteosarcoma cells by its interaction with NMDA receptor.
    Journal of cellular physiology, 2017, Volume: 232, Issue:11

    Topics: 2-Methoxyestradiol; Antineoplastic Agents; Binding Sites; Bone Neoplasms; Breast Neoplasms; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Energy Metabolism; Estradiol; Female; Glycine; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Molecular Docking Simulation; Molecular Dynamics Simulation; Nerve Tissue Proteins; Nitric Oxide Synthase Type I; Osteosarcoma; Protein Binding; Protein Domains; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Structure-Activity Relationship; Time Factors; Tubulin Modulators

2017
c-Jun NH2-terminal kinase activation is essential for DRAM-dependent induction of autophagy and apoptosis in 2-methoxyestradiol-treated Ewing sarcoma cells.
    Cancer research, 2009, Sep-01, Volume: 69, Issue:17

    Topics: 2-Methoxyestradiol; Apoptosis; Autophagy; Bone Neoplasms; Cell Line, Tumor; Enzyme Activation; Estradiol; Humans; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; Proteins; Sarcoma, Ewing; Signal Transduction; Tubulin Modulators; Tumor Suppressor Protein p53; Up-Regulation

2009
In vivo dynamics and distinct functions of hypoxia in primary tumor growth and organotropic metastasis of breast cancer.
    Cancer research, 2010, May-15, Volume: 70, Issue:10

    Topics: 2-Methoxyestradiol; Animals; Biomarkers, Tumor; Bone Neoplasms; Breast Neoplasms; Estradiol; Female; Gene Expression Profiling; Genes, Dominant; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mice; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Prognosis; Survival Rate; Tubulin Modulators; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2010
Regulation of interferon pathway in 2-methoxyestradiol-treated osteosarcoma cells.
    BMC cancer, 2012, Mar-19, Volume: 12

    Topics: 2-Methoxyestradiol; Bone Neoplasms; Cell Line, Tumor; Estradiol; Eukaryotic Initiation Factor-2; Gene Expression Regulation, Neoplastic; Humans; Interferons; Osteosarcoma; Promoter Regions, Genetic; Signal Transduction; Transcription, Genetic

2012
TNFalpha potentiates 2-methoxyestradiol-induced mitochondrial death pathway.
    Annals of the New York Academy of Sciences, 2003, Volume: 1010

    Topics: 2-Methoxyestradiol; Apoptosis; Bone Neoplasms; Cell Death; Cell Line, Tumor; Drug Synergism; Estradiol; Humans; Mitochondria; Sarcoma, Ewing; Tumor Necrosis Factor-alpha

2003
[Report of the National Oncology Research and Developement Consortium, 2003].
    Magyar onkologia, 2004, Volume: 48, Issue:1

    Topics: 2-Methoxyestradiol; Adult; Animals; Antineoplastic Agents; Biomarkers, Tumor; Biomedical Research; Bone Neoplasms; Breast Neoplasms; Child; Colorectal Neoplasms; Disease Models, Animal; Disease Progression; DNA Methylation; Epoetin Alfa; Erythropoietin; Estradiol; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genetic Markers; Head and Neck Neoplasms; Heparin, Low-Molecular-Weight; Humans; Hungary; Incidence; Male; Melanoma; Microsatellite Repeats; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Polymorphism, Genetic; Predictive Value of Tests; Recombinant Proteins; Transplantation, Heterologous

2004
Double-stranded RNA-dependent protein kinase is involved in 2-methoxyestradiol-mediated cell death of osteosarcoma cells.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2007, Volume: 22, Issue:1

    Topics: 2-Methoxyestradiol; Apoptosis; Bone Neoplasms; Cell Death; Cell Division; Cell Line, Tumor; Estradiol; Humans; Osteosarcoma; Protein Kinase Inhibitors; Protein Kinases; RNA, Double-Stranded

2007
2-Methoxyestradiol suppresses osteolytic breast cancer tumor progression in vivo.
    Cancer research, 2007, Nov-01, Volume: 67, Issue:21

    Topics: 2-Methoxyestradiol; Animals; Bone Neoplasms; Cell Line, Tumor; Disease Progression; Dose-Response Relationship, Drug; Estradiol; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Osteoclasts; Osteolysis

2007
2-methoxyestradiol induces interferon gene expression and apoptosis in osteosarcoma cells.
    Bone, 2002, Volume: 30, Issue:2

    Topics: 2-Methoxyestradiol; Animals; Apoptosis; Bone Matrix; Bone Neoplasms; Cell Survival; Cytokines; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; Gene Expression Regulation, Neoplastic; Growth Substances; Humans; Interferons; Osteoblasts; Osteosarcoma; Rats; Tumor Cells, Cultured

2002