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2-methoxyestradiol and Angiogenesis, Pathologic

2-methoxyestradiol has been researched along with Angiogenesis, Pathologic in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (14.29)	18.2507
2000's	20 (47.62)	29.6817
2010's	13 (30.95)	24.3611
2020's	3 (7.14)	2.80

Authors

Authors	Studies
Bulman, AL; Garst, ME; Macdonald, TL; Miller, TA; Thompson, CD	1
Choi, HK; Lee, K; Xia, Y	1
Han, JX; Kasim, V; Luo, LL; Wu, SR	1
He, S; Lou, Q; Luo, J; Shi, C; Yin, Z; Zhai, G; Zhang, X; Zheng, F	1
Ba, M; Duan, Y; Liu, H; Qin, J; Sun, M; Yao, Y; Yu, D; Zhang, Y	1
Chen, L; Mao, Y; Song, J; Wu, Z; Yang, C; Yuan, J; Zhang, L; Zhu, W; Zou, X	1
Dalman, RL; Fu, W; Ge, Y; Huang, J; Michie, SA; Wang, L; Wang, W; Wang, Y; Xu, B; Xuan, H	1
Hales, DB; Hales, K; Pal, P; Petrik, J	1
Chen, C; Hou, L; Li, H; Shi, J; Shi, X; Wang, L; Zhang, C; Zhang, H; Zhang, M; Zhang, Z	1
Evans, CE; Grover, SP; Humphries, J; Lyons, OT; Modarai, B; Patel, AP; Patel, AS; Saha, P; Smith, A; Waltham, M	1
Dong, X; Jiang, X; Li, G; Li, J; Ma, L; Ni, S; Qiao, H; Sun, X; Zhao, D; Zhu, H	1
Chen, L; Guo, S; Lin, Y; Yu, F; Zhan, T	1
Chen, L; Mao, Y; Zhou, L; Zhu, W; Zou, X	1
Banquerigo, ML; Brahn, E; Fogler, WE; Lee, JK; Park, EJ; Plum, SM	1
Dragun, D; Haase-Fielitz, A	1
Fogler, WE; Moore, EG; Park, EJ; Plum, SM; Sidor, CF; Strawn, SJ	1
Dubey, RK; Jackson, EK	1
Borahay, MA; Botting, S; Diaz-Arrastia, CR; Hamed, AA; Kamel, MW; Kilic, GS; Saeed, M; Salama, SA; Salih, SM; Williams, MY	1
Hu, G; Kang, Y; Lu, X; Wei, Y; Yan, CH; Yuan, M	1
Kavallaris, M; Munoz, MA; Pasquier, E; Sinnappan, S	1
Kalluri, R; Kanasaki, K; Shenoy, V	1
Cascales, P; Leon, J; Machado-Linde, F; Parrilla, JJ; Pelegrin, P; Sanchez-Ferrer, ML	1
Anderson, KC; Catley, L; Chauhan, D; Gupta, D; Hideshima, T; Leblanc, R; Li, G; Munshi, N; Podar, K; Richardson, P; Sattler, M; Schlossman, RL; Weller, E	1
Escuin, D; Giannakakou, P; Johnson, MS; LaVallee, TM; Mabjeesh, NJ; Pribluda, VS; Simons, JW; Swartz, GM; Willard, MT; Zhong, H	1
Mooberry, SL	1
Lippert, TH; Mueck, AO; Seeger, H	1
Bertola, A; Boccadoro, M; Bruno, B; Giaccone, L; Massaia, M; Palumbo, A; Rotta, M	1
Davoodpour, P; Landström, M	1
Fukuoka, M; Kinuya, S; Michigishi, T; Mori, H; Shiba, K; Shuke, N; Tonami, N; Watanabe, N; Yokoyama, K	1
Neuhaus, P; Schumacher, G	2
Chander, SK; Foster, PA; Leese, MP; Newman, SP; Potter, BV; Purohit, A; Reed, MJ	1
Choi, Y; Jung, KH; Kim, BT; Lee, I; Lee, KH; Seong Choe, Y; Young Choi, J	1
Becker, CM; Bernhardt, W; Birsner, A; Cramer, T; D'Amato, RJ; Folkman, J; Funakoshi, T; Rohwer, N	1
Adlercreutz, H; Fotsis, T; Montesano, R; Nawroth, PP; Pepper, MS; Schweigerer, L; Zhang, Y	1
Green, SJ; Pribluda, VS	1
Conney, AH; Zhu, BT	1
Atkinson, EN; Cristiano, RJ; Kataoka, M; Mukhopadhyay, T; Roth, JA; Schumacher, G	1
Arbiser, JL; D'Amato, RJ; Flynn, E; Klauber, N; Panigrathy, D; Rupnick, M; Udagawa, T	1
Green, SJ; Gubish, ER; Lavallee, TM; Pribluda, VS; Swartz, GM; Treston, A	1
Das, U	1

Reviews

13 review(s) available for 2-methoxyestradiol and Angiogenesis, Pathologic

Article	Year
Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors. European journal of medicinal chemistry, 2012, Volume: 49 Topics: Animals; Antineoplastic Agents; Drug Discovery; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1; Models, Molecular; Neoplasms; Neovascularization, Pathologic; Small Molecule Libraries	2012
Low catechol-O-methyltransferase and 2-methoxyestradiol in preeclampsia: more than a unifying hypothesis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:1 Topics: 2-Methoxyestradiol; Animals; Catechol O-Methyltransferase; Endothelium, Vascular; Estradiol; Female; Humans; Mice; Models, Biological; Neovascularization, Pathologic; Pre-Eclampsia; Pregnancy; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1	2009
Potential vascular actions of 2-methoxyestradiol. Trends in endocrinology and metabolism: TEM, 2009, Volume: 20, Issue:8 Topics: 2-Methoxyestradiol; Animals; Cardiovascular Diseases; Estradiol; Humans; Models, Biological; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Pathologic; Tubulin Modulators	2009
Pre-eclampsia: connecting angiogenic and metabolic pathways. Trends in endocrinology and metabolism: TEM, 2010, Volume: 21, Issue:9 Topics: 2-Methoxyestradiol; Catechol O-Methyltransferase; Estradiol; Female; Humans; Neovascularization, Pathologic; Pre-Eclampsia; Pregnancy	2010
2-methoxyestradiol in the pathophysiology of endometriosis: focus on angiogenesis and therapeutic potential. Reproductive sciences (Thousand Oaks, Calif.), 2012, Volume: 19, Issue:10 Topics: 2-Methoxyestradiol; Animals; Apoptosis; Cell Proliferation; Endometriosis; Estradiol; Female; Humans; Mice; Neovascularization, Pathologic; Rats; Receptors, Estrogen	2012
New insights into 2-methoxyestradiol, a promising antiangiogenic and antitumor agent. Current opinion in oncology, 2003, Volume: 15, Issue:6 Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Animals; Bone Marrow Neoplasms; Estradiol; Humans; Multiple Myeloma; Neovascularization, Pathologic	2003
[Estrogen-dependent neoplasia - what is the significance of estradiol metabolites]. Zentralblatt fur Gynakologie, 2003, Volume: 125, Issue:11 Topics: 2-Methoxyestradiol; Anticarcinogenic Agents; Breast Neoplasms; Estradiol; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Male; Neovascularization, Pathologic; Neovascularization, Physiologic; Postmenopause; Prostatic Neoplasms	2003
New drugs for treatment of multiple myeloma. The Lancet. Oncology, 2004, Volume: 5, Issue:7 Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Clinical Trials as Topic; Diphosphonates; Enzyme Inhibitors; Estradiol; Humans; Multiple Myeloma; Neovascularization, Pathologic; Oxides; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Thalidomide	2004
[2-Methoxyestradiol -- a new compound for cancer treatment]. Deutsche medizinische Wochenschrift (1946), 2006, Apr-13, Volume: 131, Issue:15 Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Apoptosis; Cell Division; Disease Models, Animal; Estradiol; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Neovascularization, Pathologic; Spindle Apparatus; Treatment Outcome; Tubulin Modulators	2006
Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis? Cancer research, 1998, Jun-01, Volume: 58, Issue:11 Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Transformation, Neoplastic; Estradiol; Female; Humans; Mammary Neoplasms, Experimental; Neovascularization, Pathologic; Tumor Cells, Cultured	1998
2-Methoxyestradiol: an endogenous antiangiogenic and antiproliferative drug candidate. Cancer metastasis reviews, 2000, Volume: 19, Issue:1-2 Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Animals; Cell Division; Cell Line; Estradiol; Humans; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Neovascularization, Pathologic; Neovascularization, Physiologic; Tumor Cells, Cultured	2000
The physiological estrogen metabolite 2-methoxyestradiol reduces tumor growth and induces apoptosis in human solid tumors. Journal of cancer research and clinical oncology, 2001, Volume: 127, Issue:7 Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Apoptosis; Cell Division; Estradiol; Humans; Neoplasms; Neovascularization, Pathologic	2001
A radical approach to cancer. Medical science monitor : international medical journal of experimental and clinical research, 2002, Volume: 8, Issue:4 Topics: 2-Methoxyestradiol; Anaerobiosis; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Division; Enzyme Inhibitors; Estradiol; Fatty Acids, Unsaturated; Free Radicals; Humans; Lipid Peroxidation; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Telomere; Thalidomide; Vitamin E	2002

Other Studies

29 other study(ies) available for 2-methoxyestradiol and Angiogenesis, Pathologic

Article	Year
Synthesis and structure-activity profiles of A-homoestranes, the estratropones. Journal of medicinal chemistry, 1997, Nov-07, Volume: 40, Issue:23 Topics: 2-Methoxyestradiol; Animals; Cattle; Colchicine; Estradiol; Estranes; Neovascularization, Pathologic; Structure-Activity Relationship; Tubulin	1997
Intramuscular injection of sotagliflozin promotes neovascularization in diabetic mice through enhancing skeletal muscle cells paracrine function. Acta pharmacologica Sinica, 2022, Volume: 43, Issue:10 Topics: 2-Methoxyestradiol; Angiogenesis Inducing Agents; Animals; Becaplermin; Culture Media, Conditioned; Diabetes Mellitus, Experimental; Glucose; Glycosides; Hindlimb; Hypoxia; Injections, Intramuscular; Ischemia; Mice; Muscle, Skeletal; Neovascularization, Pathologic; Neovascularization, Physiologic; Sodium-Glucose Transporter 2 Inhibitors; Vascular Endothelial Growth Factor A	2022
Deletion of narfl leads to increased oxidative stress mediated abnormal angiogenesis and digestive organ defects in zebrafish. Redox biology, 2020, Volume: 28 Topics: 2-Methoxyestradiol; Animals; Disease Models, Animal; Embryonic Development; Gastrointestinal Tract; Gene Expression Regulation, Developmental; Gene Knockout Techniques; Hypoxia-Inducible Factor 1, alpha Subunit; Iron-Sulfur Proteins; Neovascularization, Pathologic; Oxidative Stress; Zebrafish; Zebrafish Proteins	2020
Synthesis and biological evaluation of new 2-methoxyestradiol derivatives: Potent inhibitors of angiogenesis and tubulin polymerization. Bioorganic chemistry, 2021, Volume: 113 Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Neoplasms, Experimental; Neovascularization, Pathologic; Polymerization; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Zebrafish	2021
Endogenous hormone 2-methoxyestradiol suppresses venous hypertension-induced angiogenesis through up- and down-regulating p53 and id-1. Journal of cellular and molecular medicine, 2018, Volume: 22, Issue:2 Topics: 2-Methoxyestradiol; Animals; Basal Ganglia; Cell Movement; Down-Regulation; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Hypoxia-Inducible Factor 1, alpha Subunit; Inhibitor of Differentiation Protein 1; Male; Microvessels; Models, Biological; Neovascularization, Pathologic; Rats, Sprague-Dawley; Tumor Suppressor Protein p53; Up-Regulation	2018
Hypoxia-inducible factor 1 in clinical and experimental aortic aneurysm disease. Journal of vascular surgery, 2018, Volume: 68, Issue:5 Topics: 2-Methoxyestradiol; Aged; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Case-Control Studies; CD4-Positive T-Lymphocytes; Chemotaxis, Leukocyte; Digoxin; Disease Models, Animal; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Male; Mice, Inbred C57BL; Middle Aged; Neovascularization, Pathologic; Pancreatic Elastase; Procollagen-Proline Dioxygenase; Signal Transduction; Up-Regulation	2018
Pro-apoptotic and anti-angiogenic actions of 2-methoxyestradiol and docosahexaenoic acid, the biologically derived active compounds from flaxseed diet, in preventing ovarian cancer. Journal of ovarian research, 2019, May-25, Volume: 12, Issue:1 Topics: 2-Methoxyestradiol; Animals; Apoptosis; Cell Line, Tumor; Chickens; Chorioallantoic Membrane; Dietary Supplements; Disease Models, Animal; Docosahexaenoic Acids; Female; Flax; Humans; MAP Kinase Signaling System; Neovascularization, Pathologic; Ovarian Neoplasms; Ovary; Seeds	2019
Single-walled carbon nanotubes mediated neovascularity targeted antitumor drug delivery system. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2013, Volume: 16, Issue:1 Topics: 2-Methoxyestradiol; Animals; Cell Line, Tumor; Drug Delivery Systems; Estradiol; Female; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Nanotubes, Carbon; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Tissue Distribution; Tubulin Modulators	2013
Antiangiogenic therapy inhibits venous thrombus resolution. Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:3 Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Animals; Axitinib; Blood Coagulation; Capillary Permeability; Collagen; Estradiol; Imidazoles; Indazoles; Macrophages; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Neutrophils; Thrombophilia; Vena Cava, Inferior; Venous Thrombosis	2014
2-Methoxyestradiol synergizes with sorafenib to suppress hepatocellular carcinoma by simultaneously dysregulating hypoxia-inducible factor-1 and -2. Cancer letters, 2014, Dec-01, Volume: 355, Issue:1 Topics: 2-Methoxyestradiol; Active Transport, Cell Nucleus; Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Hepatocellular; Cell Proliferation; Cyclin D1; Dose-Response Relationship, Drug; Drug Synergism; Estradiol; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; RNA Interference; Signal Transduction; Sorafenib; Time Factors; Transfection; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays	2014
HGF expression induced by HIF-1α promote the proliferation and tube formation of endothelial progenitor cells. Cell biology international, 2015, Volume: 39, Issue:3 Topics: 2-Methoxyestradiol; Animals; Cell Culture Techniques; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Cobalt; Collagen; Drug Combinations; Endothelial Progenitor Cells; Estradiol; Gene Expression; Hepatocyte Growth Factor; Hypoxia-Inducible Factor 1, alpha Subunit; Laminin; Neovascularization, Pathologic; Proteoglycans; Rats; Receptors, Tachykinin	2015
Effectiveness of 2-methoxyestradiol in alleviating angiogenesis induced by intracranial venous hypertension. Journal of neurosurgery, 2016, Volume: 125, Issue:3 Topics: 2-Methoxyestradiol; Animals; Disease Models, Animal; Estradiol; Intracranial Hypertension; Male; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Treatment Outcome	2016
An angiogenesis inhibitor, 2-methoxyestradiol, involutes rat collagen-induced arthritis and suppresses gene expression of synovial vascular endothelial growth factor and basic fibroblast growth factor. The Journal of rheumatology, 2008, Volume: 35, Issue:11 Topics: 2-Methoxyestradiol; Animals; Arthritis, Experimental; Autoantibodies; Collagen; Disease Models, Animal; Endothelial Growth Factors; Estradiol; Fibroblast Growth Factor 2; Gastric Lavage; Gene Expression; Immunohistochemistry; Infusion Pumps; Neovascularization, Pathologic; Radiography; Rats; Rats, Inbred Strains; Synovial Membrane; Tubulin Modulators; von Willebrand Factor	2008
Disease modifying and antiangiogenic activity of 2-methoxyestradiol in a murine model of rheumatoid arthritis. BMC musculoskeletal disorders, 2009, May-01, Volume: 10 Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Angiogenic Proteins; Animals; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Vessels; Bone Resorption; Cartilage, Articular; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Female; Joints; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Synovial Membrane; Synovitis; Time Factors; Treatment Outcome	2009
Catechol-o-methyltransferase expression and 2-methoxyestradiol affect microtubule dynamics and modify steroid receptor signaling in leiomyoma cells. PloS one, 2009, Oct-07, Volume: 4, Issue:10 Topics: 2-Methoxyestradiol; Apoptosis; Aromatase; Catechol O-Methyltransferase; Estradiol; Estrogen Receptor alpha; Female; Humans; Leiomyoma; Microtubules; Neovascularization, Pathologic; Receptors, Progesterone; Receptors, Steroid; Signal Transduction; Tumor Necrosis Factor-alpha; Uterine Neoplasms	2009
In vivo dynamics and distinct functions of hypoxia in primary tumor growth and organotropic metastasis of breast cancer. Cancer research, 2010, May-15, Volume: 70, Issue:10 Topics: 2-Methoxyestradiol; Animals; Biomarkers, Tumor; Bone Neoplasms; Breast Neoplasms; Estradiol; Female; Gene Expression Profiling; Genes, Dominant; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mice; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Prognosis; Survival Rate; Tubulin Modulators; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2010
ENMD-1198, a new analogue of 2-methoxyestradiol, displays both antiangiogenic and vascular-disrupting properties. Molecular cancer therapeutics, 2010, Volume: 9, Issue:5 Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Blood Vessels; Cell Movement; Cell Proliferation; Cells, Cultured; Cytoskeleton; Drug Evaluation, Preclinical; Endothelial Cells; Estradiol; Estrenes; Humans; Male; Neovascularization, Pathologic; Neovascularization, Physiologic; Tubulin Modulators	2010
2-Methoxyestradiol overcomes drug resistance in multiple myeloma cells. Blood, 2002, Sep-15, Volume: 100, Issue:6 Topics: 2-Methoxyestradiol; Animals; Apoptosis; Bone Marrow Cells; Cytokines; Drug Resistance; Estradiol; Humans; Mice; Mice, SCID; Mitochondrial Proteins; Multiple Myeloma; Neoplasms, Experimental; Neovascularization, Pathologic; Signal Transduction; Stromal Cells; Tumor Cells, Cultured	2002
2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF. Cancer cell, 2003, Volume: 3, Issue:4 Topics: 2-Methoxyestradiol; Animals; Blotting, Northern; Breast Neoplasms; DNA-Binding Proteins; Endothelial Growth Factors; Estradiol; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Lymphokines; Mice; Microscopy, Confocal; Microtubules; Models, Animal; Neovascularization, Pathologic; Nuclear Proteins; RNA, Messenger; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2003
The new cancer blockers. The Johns Hopkins medical letter health after 50, 2004, Volume: 17, Issue:8 Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Estradiol; Humans; Neoplasms; Neovascularization, Pathologic; Thalidomide; Tissue Extracts	2004
2-Methoxyestradiol-induced apoptosis in prostate cancer cells requires Smad7. The Journal of biological chemistry, 2005, Apr-15, Volume: 280, Issue:15 Topics: 2-Methoxyestradiol; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; beta Catenin; Blotting, Western; Carrier Proteins; Cell Line, Tumor; Cell Nucleus; Cytoskeletal Proteins; DNA-Binding Proteins; Estradiol; Humans; Male; Membrane Proteins; Neovascularization, Pathologic; p38 Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins; RNA; RNA, Small Interfering; Signal Transduction; Smad7 Protein; Time; Time Factors; Trans-Activators; Transforming Growth Factor beta	2005
Anti-angiogenic therapy and chemotherapy affect 99mTc sestamibi and 99mTc-HL91 accumulation differently in tumour xenografts. Nuclear medicine communications, 2005, Volume: 26, Issue:12 Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Estradiol; Fluorouracil; Humans; Hypoxia; Kinetics; Mice; Neoplasm Transplantation; Neovascularization, Pathologic; Organotechnetium Compounds; Oximes; Oxygen; Radiopharmaceuticals; Technetium Tc 99m Sestamibi; Time Factors	2005
In vivo inhibition of angiogenesis by sulphamoylated derivatives of 2-methoxyoestradiol. British journal of cancer, 2007, May-07, Volume: 96, Issue:9 Topics: 2-Methoxyestradiol; Animals; Breast Neoplasms; Cell Division; Cell Line, Tumor; Collagen; Drug Combinations; Estradiol; Female; Humans; Laminin; Mice; Mice, Nude; Neovascularization, Pathologic; Proteoglycans; Transplantation, Heterologous; Tubulin Modulators	2007
2-[methyl-(11)C]methoxyestradiol: synthesis, evaluation and pharmacokinetics for in vivo studies on angiogenesis. Nuclear medicine and biology, 2007, Volume: 34, Issue:6 Topics: 2-Methoxyestradiol; Animals; Area Under Curve; Biotransformation; Carbon Radioisotopes; Carcinoma, Lewis Lung; Cells, Cultured; Chromatography, High Pressure Liquid; Estradiol; Half-Life; Humans; Indicators and Reagents; Mice; Muscle, Smooth, Vascular; Neoplasm Transplantation; Neovascularization, Pathologic; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution	2007
2-methoxyestradiol inhibits hypoxia-inducible factor-1{alpha} and suppresses growth of lesions in a mouse model of endometriosis. The American journal of pathology, 2008, Volume: 172, Issue:2 Topics: 2-Methoxyestradiol; Angiogenesis Inhibitors; Animals; Blotting, Western; Capillary Permeability; Cell Hypoxia; Disease Models, Animal; Endometriosis; Estradiol; Female; Gene Expression; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A	2008
The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth. Nature, 1994, Mar-17, Volume: 368, Issue:6468 Topics: 2-Methoxyestradiol; 3T3 Cells; Administration, Oral; Animals; Antineoplastic Agents; Cattle; Cells, Cultured; Drug Screening Assays, Antitumor; Endothelium, Vascular; Estradiol; Fibroblast Growth Factor 2; Humans; Melanoma, Experimental; Mice; Neovascularization, Pathologic; Sarcoma, Experimental; Tumor Cells, Cultured	1994
A good estrogen. Science (New York, N.Y.), 1998, May-15, Volume: 280, Issue:5366 Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Catechol O-Methyltransferase; Estradiol; Humans; Lung Neoplasms; Melanoma; Neovascularization, Pathologic	1998
An agent that increases tumor suppressor transgene product coupled with systemic transgene delivery inhibits growth of metastatic lung cancer in vivo. Cancer research, 1998, Nov-01, Volume: 58, Issue:21 Topics: 2-Methoxyestradiol; Adenoviridae; Estradiol; Genes, p53; Genetic Therapy; Genetic Vectors; Humans; Lung Neoplasms; Neovascularization, Pathologic; Tumor Cells, Cultured; Tumor Suppressor Protein p53	1998
The antiangiogenic agents TNP-470 and 2-methoxyestradiol inhibit the growth of angiosarcoma in mice. Journal of the American Academy of Dermatology, 1999, Volume: 40, Issue:6 Pt 1 Topics: 2-Methoxyestradiol; Animals; Cyclohexanes; Endothelium, Vascular; Estradiol; Hemangioendothelioma; Hemangiosarcoma; Male; Mice; Mice, Nude; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Sesquiterpenes	1999