2-linoleoylglycerol and Disease-Models--Animal

We have investigated the effects of 0.001mg/kg 2-arachidonoylglycerol (2-AG) administered in combination with compounds present in the body alongside 2-AG like 2-palmitoylglycerol and 2-linoleylglycerol (also termed "entourage"), on cognitive function,food intake, and neurotransmitter levels in the hippocampus and hypothalamus of mice under diet restriction. Young female Sabra mice were treated with vehicle, 2-AG, 2-AG+entourage, 2-AG+entourage+5-(4-Chlorophenyl)-1-(2,4-dichloro-phenyl)- 4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide (SR141716A, a CB

Topics: Animals; Anorexia Nervosa; Arachidonic Acids; Cannabinoid Receptor Modulators; Cognition; Disease Models, Animal; Dopamine; Eating; Endocannabinoids; Female; Glycerides; Hippocampus; Hypothalamus; Levodopa; Mice; Neurotransmitter Agents; Random Allocation