2-keto-4-methylvalerate has been researched along with Nephrotic Syndrome in 1 studies
alpha-ketoisocaproic acid: RN given refers to parent cpd
4-methyl-2-oxopentanoate : A 2-oxo monocarboxylic acid anion that is the conjugate base of 4-methyl-2-oxopentanoic acid.
4-methyl-2-oxopentanoic acid : A 2-oxo monocarboxylic acid that is pentanoic acid (valeric acid) substituted with a keto group at C-2 and a methyl group at C-4. A metabolite that has been found to accumulate in maple syrup urine disease.
Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Whole-body leucine flux was measured in eight patients with nephrotic syndrome and in five healthy subjects by primed-constant infusion of L-[1-13C leucine]." | 9.08 | Leucine turnover in patients with nephrotic syndrome: evidence suggesting body protein conservation. ( Flanigan, MJ; Kopple, JD; Lim, VS; Wolfson, M; Yarasheski, KE, 1998) |
| "Whole-body leucine flux was measured in eight patients with nephrotic syndrome and in five healthy subjects by primed-constant infusion of L-[1-13C leucine]." | 5.08 | Leucine turnover in patients with nephrotic syndrome: evidence suggesting body protein conservation. ( Flanigan, MJ; Kopple, JD; Lim, VS; Wolfson, M; Yarasheski, KE, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lim, VS | 1 |
| Wolfson, M | 1 |
| Yarasheski, KE | 1 |
| Flanigan, MJ | 1 |
| Kopple, JD | 1 |
1 trial available for 2-keto-4-methylvalerate and Nephrotic Syndrome
| Article | Year |
|---|---|
Leucine turnover in patients with nephrotic syndrome: evidence suggesting body protein conservation.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Diet, Protein-Restricted; Double-Blind Method | 1998 |