2-keto-4-methylvalerate has been researched along with Mitochondrial Diseases in 2 studies
alpha-ketoisocaproic acid: RN given refers to parent cpd
4-methyl-2-oxopentanoate : A 2-oxo monocarboxylic acid anion that is the conjugate base of 4-methyl-2-oxopentanoic acid.
4-methyl-2-oxopentanoic acid : A 2-oxo monocarboxylic acid that is pentanoic acid (valeric acid) substituted with a keto group at C-2 and a methyl group at C-4. A metabolite that has been found to accumulate in maple syrup urine disease.
Mitochondrial Diseases: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amaral, AU | 1 |
| Leipnitz, G | 1 |
| Fernandes, CG | 1 |
| Seminotti, B | 1 |
| Schuck, PF | 1 |
| Wajner, M | 1 |
| Parra, D | 1 |
| González, A | 1 |
| Mugueta, C | 1 |
| Martínez, A | 1 |
| Monreal, I | 1 |
1 review available for 2-keto-4-methylvalerate and Mitochondrial Diseases
| Article | Year |
|---|---|
Laboratory approach to mitochondrial diseases.
Topics: Breath Tests; DNA, Mitochondrial; Humans; Keto Acids; MERRF Syndrome; Mitochondria; Mitochondrial Di | 2001 |
1 other study available for 2-keto-4-methylvalerate and Mitochondrial Diseases
| Article | Year |
|---|---|
Alpha-ketoisocaproic acid and leucine provoke mitochondrial bioenergetic dysfunction in rat brain.
Topics: Animals; Brain; Central Nervous System Agents; Electron Transport; Homeostasis; Keto Acids; Ketoglut | 2010 |