2-keto-4-methylvalerate has been researched along with Chronic Illness in 3 studies
alpha-ketoisocaproic acid: RN given refers to parent cpd
4-methyl-2-oxopentanoate : A 2-oxo monocarboxylic acid anion that is the conjugate base of 4-methyl-2-oxopentanoic acid.
4-methyl-2-oxopentanoic acid : A 2-oxo monocarboxylic acid that is pentanoic acid (valeric acid) substituted with a keto group at C-2 and a methyl group at C-4. A metabolite that has been found to accumulate in maple syrup urine disease.
Excerpt | Relevance | Reference |
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"To evaluate the effects of chronic metabolic acidosis on protein dynamics and amino acid oxidation in the human kidney, a combination of organ isotopic ((14)C-leucine) and mass-balance techniques in 11 subjects with normal renal function undergoing venous catheterizations was used." | 3.72 | Kidney protein dynamics and ammoniagenesis in humans with chronic metabolic acidosis. ( Deferrari, G; Garibotto, G; Procopio, V; Robaudo, C; Russo, R; Saffioti, S; Sala, MR; Sofia, A; Tessari, P; Verzola, D; Vettore, M, 2004) |
"The ability of chronic endogenous hyperinsulinemia to induce a resistance to insulin action on protein and glucose metabolism was studied in 10 subjects affected by a benign (functioning) insulinoma and 18 healthy subjects by means of infusions of [1-(14)C]leucine and [3-(3)H] glucose." | 3.69 | Defective insulin action on protein and glucose metabolism during chronic hyperinsulinemia in subjects with benign insulinoma. ( Battezzati, A; Bianchi, E; Di Carlo, V; Luzi, L; Perseghin, G; Pozza, G; Terruzzi, I, 1995) |
"We measured leucine flux rates during infusions of L-[1-14C]- and L-[1-1C]leucine in fetal sheep exposed to maternal insulin-induced hypoglycemia over the last 8 wk (40%) of gestation to determine effects of chronic glucose deficiency and hypoglycemia on fetal leucine metabolism." | 3.69 | Leucine metabolism in chronically hypoglycemic hypoinsulinemic growth-restricted fetal sheep. ( Carver, TD; Fennessey, PV; Hay, WW; Pike, AW; Quick, AA; Teng, CC, 1997) |
"The ability of chronic endogenous hyperinsulinemia to induce a resistance to insulin action on protein and glucose metabolism was studied in 10 subjects affected by a benign (functioning) insulinoma and 18 healthy subjects by means of infusions of [1-(14)C]leucine and [3-(3)H] glucose." | 1.29 | Defective insulin action on protein and glucose metabolism during chronic hyperinsulinemia in subjects with benign insulinoma. ( Battezzati, A; Bianchi, E; Di Carlo, V; Luzi, L; Perseghin, G; Pozza, G; Terruzzi, I, 1995) |
Timeframe | Studies, this research(%) | All Research% |
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pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (66.67) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Garibotto, G | 1 |
Sofia, A | 1 |
Robaudo, C | 1 |
Saffioti, S | 1 |
Sala, MR | 1 |
Verzola, D | 1 |
Vettore, M | 1 |
Russo, R | 1 |
Procopio, V | 1 |
Deferrari, G | 1 |
Tessari, P | 1 |
Battezzati, A | 1 |
Terruzzi, I | 1 |
Perseghin, G | 1 |
Bianchi, E | 1 |
Di Carlo, V | 1 |
Pozza, G | 1 |
Luzi, L | 1 |
Carver, TD | 1 |
Quick, AA | 1 |
Teng, CC | 1 |
Pike, AW | 1 |
Fennessey, PV | 1 |
Hay, WW | 1 |
3 other studies available for 2-keto-4-methylvalerate and Chronic Illness
Article | Year |
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Kidney protein dynamics and ammoniagenesis in humans with chronic metabolic acidosis.
Topics: Acidosis; Adult; Amino Acids; Ammonia; Catheterization; Chronic Disease; Female; Glomerular Filtrati | 2004 |
Defective insulin action on protein and glucose metabolism during chronic hyperinsulinemia in subjects with benign insulinoma.
Topics: Adult; Blood Glucose; Carbon Radioisotopes; Chronic Disease; Glucose; Glucose Clamp Technique; Human | 1995 |
Leucine metabolism in chronically hypoglycemic hypoinsulinemic growth-restricted fetal sheep.
Topics: Animals; Blood Glucose; Body Weight; Carbon Isotopes; Chronic Disease; Female; Fetal Blood; Fetal Gr | 1997 |