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2-keto-4-methylvalerate and Cardiometabolic Syndrome

2-keto-4-methylvalerate has been researched along with Cardiometabolic Syndrome in 2 studies

alpha-ketoisocaproic acid: RN given refers to parent cpd
4-methyl-2-oxopentanoate : A 2-oxo monocarboxylic acid anion that is the conjugate base of 4-methyl-2-oxopentanoic acid.
4-methyl-2-oxopentanoic acid : A 2-oxo monocarboxylic acid that is pentanoic acid (valeric acid) substituted with a keto group at C-2 and a methyl group at C-4. A metabolite that has been found to accumulate in maple syrup urine disease.

Cardiometabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components not only include metabolic dysfunctions of METABOLIC SYNDROME but also HYPERTENSION, and ABDOMINAL OBESITY.

Research Excerpts

ExcerptRelevanceReference
"Elevated plasma homocysteine has been reported in individuals with diseases of the metabolic syndrome including vascular disease and insulin resistance."7.73Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion. ( Brennan, L; Flatt, PR; McClenaghan, NH; Newsholme, P; Patterson, S, 2006)
"Elevated plasma homocysteine has been reported in individuals with diseases of the metabolic syndrome including vascular disease and insulin resistance."3.73Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion. ( Brennan, L; Flatt, PR; McClenaghan, NH; Newsholme, P; Patterson, S, 2006)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mellouk, Z1
Zhang, Y1
Bulur, N1
Louchami, K1
Malaisse, WJ1
Ait Yahia, D1
Sener, A1
Patterson, S1
Flatt, PR1
Brennan, L1
Newsholme, P1
McClenaghan, NH1

Other Studies

2 other studies available for 2-keto-4-methylvalerate and Cardiometabolic Syndrome

ArticleYear
The metabolic syndrome of fructose-fed rats: effects of long-chain polyunsaturated ω3 and ω6 fatty acids. III. Secretory behaviour of isolated pancreatic islets.
    International journal of molecular medicine, 2012, Volume: 29, Issue:2

    Topics: Animals; Diet; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fructose; Glucose; Insulin; Insulin Secre

2012
Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion.
    The Journal of endocrinology, 2006, Volume: 189, Issue:2

    Topics: Alanine; Arginine; Calcium; Carbachol; Clone Cells; Colforsin; Culture Media; Dose-Response Relation

2006
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