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2-keto-4-methylvalerate and Alloxan Diabetes

2-keto-4-methylvalerate has been researched along with Alloxan Diabetes in 10 studies

alpha-ketoisocaproic acid: RN given refers to parent cpd
4-methyl-2-oxopentanoate : A 2-oxo monocarboxylic acid anion that is the conjugate base of 4-methyl-2-oxopentanoic acid.
4-methyl-2-oxopentanoic acid : A 2-oxo monocarboxylic acid that is pentanoic acid (valeric acid) substituted with a keto group at C-2 and a methyl group at C-4. A metabolite that has been found to accumulate in maple syrup urine disease.

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19908 (80.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stec, DF1
Wang, S1
Stothers, C1
Avance, J1
Denson, D1
Harris, R1
Voziyan, P1
Grill, V2
Efendić, S1
Giroix, MH1
Portha, B1
Kergoat, M1
Bailbe, D1
Picon, L1
Kilberg, MS1
Gwynn, MB1
Patston, PA1
Espinal, J1
Randle, PJ1
Hutson, SM1
Harper, AE1
Sterniczuk, A1
Wałajtys-Rode, EI1
Wojtczak, AB1
Rundfeldt, M1
Brosnan, ME1
Lowry, A1
Brosnan, JT1
Aftring, RP1
Manos, PN1
Buse, MG1

Other Studies

10 other studies available for 2-keto-4-methylvalerate and Alloxan Diabetes

ArticleYear
Alterations of urinary metabolite profile in model diabetic nephropathy.
    Biochemical and biophysical research communications, 2015, Jan-09, Volume: 456, Issue:2

    Topics: Aconitic Acid; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitu

2015
Abnormal D cell secretion in alloxan-diabetes: influence by drug and aberrant metabolism.
    The American journal of physiology, 1984, Volume: 246, Issue:6 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Alloxan; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experi

1984
Glucose insensitivity and amino-acid hypersensitivity of insulin release in rats with non-insulin-dependent diabetes. A study with the perfused pancreas.
    Diabetes, 1983, Volume: 32, Issue:5

    Topics: Acetylcholine; Amino Acids; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Gluco

1983
Plasma membrane transport of 2-ketoisocaproate by rat hepatocytes in primary culture.
    The Journal of biological chemistry, 1983, Oct-10, Volume: 258, Issue:19

    Topics: Animals; Biological Transport; Cell Membrane; Cells, Cultured; Dexamethasone; Diabetes Mellitus, Exp

1983
Effects of diet and of alloxan-diabetes on the activity of branched-chain 2-oxo acid dehydrogenase complex and of activator protein in rat tissues.
    The Biochemical journal, 1984, Sep-15, Volume: 222, Issue:3

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Cell Fractionation; Diabetes Mellitus, E

1984
Blood and tissue branched-chain amino and alpha-keto acid concentrations: effect of diet, starvation, and disease.
    The American journal of clinical nutrition, 1981, Volume: 34, Issue:2

    Topics: Amino Acids, Branched-Chain; Animals; Diabetes Mellitus, Experimental; Diet; Hemiterpenes; Humans; I

1981
Decarboxylation of branched-chain alpha-ketoacids in hepatocytes from alloxan-diabetic rats. The effect of insulin.
    Cell biochemistry and function, 1991, Volume: 9, Issue:1

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Decarboxylation; Diabetes Mellitus, Expe

1991
Abnormalities of insulin responses after ambient and previous exposure to glucose in streptozocin-diabetic and dexamethasone-treated rats. Role of hyperglycemia and increased B-cell demands.
    Diabetes, 1986, Volume: 35, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Dexamethasone; Diabetes Mellitus, Experimental;

1986
Diabetes increases active fraction of branched-chain 2-oxoacid dehydrogenase in rat brain.
    Diabetes, 1986, Volume: 35, Issue:9

    Topics: Animals; Brain; Diabetes Mellitus, Experimental; Enzyme Activation; Keto Acids; Male; Rats; Rats, In

1986
Catabolism of branched-chain amino acids by diaphragm muscles of fasted and diabetic rats.
    Metabolism: clinical and experimental, 1985, Volume: 34, Issue:8

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amination; Amino Acids, Branched-Chain; Animals;

1985