2-keto-4-methylvalerate has been researched along with Alcoholic Cirrhosis in 4 studies
alpha-ketoisocaproic acid: RN given refers to parent cpd
4-methyl-2-oxopentanoate : A 2-oxo monocarboxylic acid anion that is the conjugate base of 4-methyl-2-oxopentanoic acid.
4-methyl-2-oxopentanoic acid : A 2-oxo monocarboxylic acid that is pentanoic acid (valeric acid) substituted with a keto group at C-2 and a methyl group at C-4. A metabolite that has been found to accumulate in maple syrup urine disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The enrichment of circulating KICA with [13C]KICA was similar in alcoholics and controls, indicating that a decreased bioavailability or an increased dilution of labeled KICA cannot account for the decreased exhalation of 13CO2." | 1.29 | Mitochondrial function reflected by the decarboxylation of [13C]ketoisocaproate is impaired in alcoholics. ( Junker, E; Lauterburg, BH; Meyer, B; Mossi, S; Witschi, A, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tarantino, G | 1 |
| Di Bernardo, C | 1 |
| Vitaglione, R | 1 |
| Cambri, S | 1 |
| Eriksson, LS | 1 |
| Hagenfeldt, L | 1 |
| Wahren, J | 1 |
| Witschi, A | 1 |
| Mossi, S | 1 |
| Meyer, B | 1 |
| Junker, E | 1 |
| Lauterburg, BH | 1 |
| Muñoz, S | 1 |
| Walser, M | 1 |
1 review available for 2-keto-4-methylvalerate and Alcoholic Cirrhosis
| Article | Year |
|---|---|
[New trends in the therapy of alcoholic hepatic diseases].
Topics: Adrenal Cortex Hormones; Amino Acids; Androgens; Animals; Antithyroid Agents; Colchicine; Enzyme Ind | 1984 |
3 other studies available for 2-keto-4-methylvalerate and Alcoholic Cirrhosis
| Article | Year |
|---|---|
Intravenous infusion of alpha-oxoisocaproate: influence on amino acid and nitrogen metabolism in patients with liver cirrhosis.
Topics: Adult; Amino Acids; Ammonia; Caproates; Female; Humans; Infusions, Parenteral; Keto Acids; Liver; Li | 1982 |
Mitochondrial function reflected by the decarboxylation of [13C]ketoisocaproate is impaired in alcoholics.
Topics: Adult; Aged; Breath Tests; Decarboxylation; Female; Humans; Keto Acids; Liver Cirrhosis, Alcoholic; | 1994 |
Utilization of alpha-ketoisocaproate for synthesis of hepatic export proteins and peripheral proteins in normal and cirrhotic subjects.
Topics: Adult; Aged; Drug Evaluation; Erythrocytes; Female; Fibrinogen; Globins; Humans; Immunoglobulin G; K | 1986 |