2-keto-4-methylvalerate has been researched along with Acidosis in 4 studies
alpha-ketoisocaproic acid: RN given refers to parent cpd
4-methyl-2-oxopentanoate : A 2-oxo monocarboxylic acid anion that is the conjugate base of 4-methyl-2-oxopentanoic acid.
4-methyl-2-oxopentanoic acid : A 2-oxo monocarboxylic acid that is pentanoic acid (valeric acid) substituted with a keto group at C-2 and a methyl group at C-4. A metabolite that has been found to accumulate in maple syrup urine disease.
Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the effects of acute metabolic acidosis and alkalosis on leucine metabolism in vivo, mongrel dogs were infused with [1-14C]leucine for 8 h, along with NaCl, HCI, or NaHCO3 over the last 4 h." | 7.67 | Effects of acute metabolic acidosis and alkalosis on leucine metabolism in conscious dogs. ( Haymond, MW; Miles, JM; Rodriguez, NR; Schwenk, WF, 1989) |
| "To evaluate the effects of chronic metabolic acidosis on protein dynamics and amino acid oxidation in the human kidney, a combination of organ isotopic ((14)C-leucine) and mass-balance techniques in 11 subjects with normal renal function undergoing venous catheterizations was used." | 3.72 | Kidney protein dynamics and ammoniagenesis in humans with chronic metabolic acidosis. ( Deferrari, G; Garibotto, G; Procopio, V; Robaudo, C; Russo, R; Saffioti, S; Sala, MR; Sofia, A; Tessari, P; Verzola, D; Vettore, M, 2004) |
| "To determine the effects of acute metabolic acidosis and alkalosis on leucine metabolism in vivo, mongrel dogs were infused with [1-14C]leucine for 8 h, along with NaCl, HCI, or NaHCO3 over the last 4 h." | 3.67 | Effects of acute metabolic acidosis and alkalosis on leucine metabolism in conscious dogs. ( Haymond, MW; Miles, JM; Rodriguez, NR; Schwenk, WF, 1989) |
| "Metabolic acidosis was induced by feeding rats 1." | 1.29 | Regulation of glutamate dehydrogenase by branched-chain amino acids in skeletal muscle from rats and chicks. ( Thompson, JR; Zhou, X, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garibotto, G | 1 |
| Sofia, A | 1 |
| Robaudo, C | 1 |
| Saffioti, S | 1 |
| Sala, MR | 1 |
| Verzola, D | 1 |
| Vettore, M | 1 |
| Russo, R | 1 |
| Procopio, V | 1 |
| Deferrari, G | 1 |
| Tessari, P | 1 |
| Zhou, X | 1 |
| Thompson, JR | 1 |
| Straumann, E | 1 |
| Keller, U | 1 |
| Küry, D | 1 |
| Bloesch, D | 1 |
| Thélin, A | 1 |
| Arnaud, MJ | 1 |
| Stauffacher, W | 1 |
| Rodriguez, NR | 1 |
| Miles, JM | 1 |
| Schwenk, WF | 1 |
| Haymond, MW | 1 |
4 other studies available for 2-keto-4-methylvalerate and Acidosis
| Article | Year |
|---|---|
Kidney protein dynamics and ammoniagenesis in humans with chronic metabolic acidosis.
Topics: Acidosis; Adult; Amino Acids; Ammonia; Catheterization; Chronic Disease; Female; Glomerular Filtrati | 2004 |
Regulation of glutamate dehydrogenase by branched-chain amino acids in skeletal muscle from rats and chicks.
Topics: Acidosis; Amino Acids, Branched-Chain; Ammonium Chloride; Animals; Chickens; Glutamate Dehydrogenase | 1996 |
Effect of acute acidosis and alkalosis on leucine kinetics in man.
Topics: Acidosis; Adult; Alkalosis; Bicarbonates; Blood Glucose; Fatty Acids, Nonesterified; Humans; Hydroge | 1992 |
Effects of acute metabolic acidosis and alkalosis on leucine metabolism in conscious dogs.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Alkalosis; Amino Acids; Animals; Bicarbonates; Blood | 1989 |