2-keto-4-methylthiobutyric acid has been researched along with Neoplasms in 2 studies
2-keto-4-methylthiobutyric acid: RN given refers to parent cpd; structure
4-methylthio-2-oxobutanoic acid : A 2-oxo monocarboxylic acid derived from L-methionine via the action of methionine transaminase.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The loss of CtBP in cancer cells resulted in the increased apoptosis due to intracellular acidification and the ablation of cancer cell metabolic homeostasis represented by decreased glutamine consumption, oxidative phosphorylation and ATP synthesis." | 1.42 | CtBP maintains cancer cell growth and metabolic homeostasis via regulating SIRT4. ( Cui, G; Di, LJ; Wang, L; Wang, Y; Zhou, H, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Korwar, S | 1 |
| Morris, BL | 1 |
| Parikh, HI | 1 |
| Coover, RA | 1 |
| Doughty, TW | 1 |
| Love, IM | 1 |
| Hilbert, BJ | 1 |
| Royer, WE | 1 |
| Kellogg, GE | 1 |
| Grossman, SR | 1 |
| Ellis, KC | 1 |
| Wang, L | 1 |
| Zhou, H | 1 |
| Wang, Y | 1 |
| Cui, G | 1 |
| Di, LJ | 1 |
2 other studies available for 2-keto-4-methylthiobutyric acid and Neoplasms
| Article | Year |
|---|---|
Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP).
Topics: Alcohol Oxidoreductases; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA-Binding Pr | 2016 |
CtBP maintains cancer cell growth and metabolic homeostasis via regulating SIRT4.
Topics: Alcohol Oxidoreductases; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Respiration; | 2015 |